Glycoproteins
Mostrando 25-36 de 2919 artigos, teses e dissertações.
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25. Avaliação das respostas imunológicas e protetora de uma vacina de DNA contra tumores induzidos por HPV-16. / Immune responses and anti-tumor therapeutic effects generated by a DNA vaccine against HPV-16-induced tumors.
No presente trabalho, desenvolvemos uma estratégia vacinal baseada em vacinas de DNA que codificam proteínas do HPV-16, o tipo viral de maior relevância epidemiológica, fusionadas à glicoproteína D (gD) do vírus herpes simplex tipo 1 (HSV-1). A vacina que contêm o gene da E7 de HPV-16 fusionada à gD de HSV-1 (pgDE7), administrada em regime vacinal d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/12/2010
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26. Doença do armazenamento lisossomal causada pela ingestão espontânea de Sida carpinifolia em cervos Sambar (Cervus unicolor) cativos no Rio de Janeiro. / Lysosomal storage disease caused by spontaneous ingestion of Sida carpinifolia in captive-Sambar deer (Cervus unicolor) in Rio de Janeiro State, Brazil.
Cases of diseases induced by toxic plants in domestic herbivores are well reported throughout the world and have been studied also in Brazil. However, not much is known about the epidemiological and pathological aspectos of these conditions in free-living wildlife or bred in captivity. The risk for developing the toxicoses in captivity has been increasing, s
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/08/2010
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27. IdentificaÃÃo de glicoproteÃnas em membrana de tumores primÃrios do sistema nervoso central utilizando lectinas vegetais acopladas a fluoresceÃna / Identification of membrane glycoproteins in tumors Primary central nervous system using lectins plant coupled with fluorescein
Lectinas sÃo proteÃnas que pertencem a um grupo heterogÃneo de molÃculas com capacidade de ligaÃÃo especÃfica e reversÃvel a carboidratos. Desde sua descoberta, as lectinas se tornaram importantes ferramentas para a investigaÃÃo de fenÃmenos como a adesÃo, a migraÃÃo e a proliferaÃÃo celular, em condiÃÃes normais e patolÃgicas. Durante o p
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/02/2010
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28. CaracterizaÃÃo BioquÃmica Parcial do LÃtex de Cryptostegia grandiflora R. Br. e AÃÃo Contra o Vetor da Dengue. / Biochemical characterization of latex of Cryptostegia grandiflora and larvicidal activity against Aedes aegypti
Cryptostegia grandiflora R. Br. is a shurb belonging to Apocynaceae family popularly known as âunha de bruxaâ. There are few studies available about the latex from this species and preliminary assays had shown its action against Dengue vector. Thus, this study aimed to characterize the biochemical properties of Cr. grandiflora latex and to evaluate the act
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/02/2010
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29. Montagem de um pseudo-hantavírus quimera, contendo a nucleoproteína do vírus Araraquara e as glicoproteínas do vírus Andes, em sistema baculovírus / Assembly of a chimeric hantavirus-like particle, containing the Araraquara nucleoprotein and the Andes glycoproteins, expressed in baculovirus system
Hantaviruses, members of the Bunyaviridae family, are the infectious agents responsible for Hemorrhagic Fever with Renal Syndrome and the Hantavirus Cardiopulmonary Syndrome. The viral genome is composed by three segments of single-stranded negative-sense RNA, designated as S, M and L, which encode, respectively, the nucleoprotein, the G1 and G2 glycoprotein
Publicado em: 2010
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30. Construção e análise das propriedades profiláticas e terapêuticas de uma vacina contra tumores associados ao HPV-16. / Construction and analysis of the prophylactic and therapeutic proprieties of a vaccine against HPV-16 associated tumors.
The development of vaccines against human papillomavirus (HPV) represents an important alternative to control the sexually transmitted infection and cervical cancer. In this paper we explored a novel vaccine strategy against tumors induced by HPV-16 using the E7 protein obtained after genetic fusion to the glycoprotein D of herpes virus type 1, a protein wit
Publicado em: 2010
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31. Clonagem e expressão da glucocerebrosidase humana em células de ovário de hamster chinês (CHO). / Cloning and expression of human glucocerebrosidase in Chinese hamster ovary (CHO) cells.
Deficiency of the lysosomal glucocerebrosidase (GCR) enzyme results in Gauchers disease. Current treatment consists on enzyme replacement therapy by the administration of recombinant GCR produced in CHO cells. However, the medicine available in the market is extremely expensive. In this work, we proposed the cloning and expression of human GCR in CHO cells,
Publicado em: 2010
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32. Caracterização molecular de Vírus Respiratório Sincicial Humano (HRSV) isolados na cidade de São Paulo no período de 2007 a 2008. / Characterization and epidemiologic of Human Respiratory Syncytial Virus (HRSV) isolated in São Paulo city in 2007-2008.
Human Respiratory Syncytial Virus (HRSV) is considered the most common cause of lower respiratory tract disease in infants and young children and are the main guilty for the elevated children hospitalizations rate under 5 years of age. The HRSV has a world-wide distribution, being able to attack all the ages however the 6 weeks to 9 months children of are th
Publicado em: 2010
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33. Expression and possible functional role of galectin-3 in the / Expressão e possível papel funcional da galectina-3 no timo de camundongos diabéticos não-obesos (NOD)
Galectin-3 belongs to a family of endogenous lectins which bind to -galactosides presented on the cell surface and extracellular matrix glycoproteins. It is involved in multiple biological functions such as cell growth, adhesion, proliferation and apoptosis. Moreover, galectin-3 is found in several tissues and organs, being highly conserved among animal spec
Publicado em: 2010
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34. Estudo das propriedades eletricas das hemacias utilizando pinça optica / Study of electrical properties of red blood cell using optical tweezers
The red blood cell (RBC) membrane contains proteins and glycoproteins embedded in a fluid lipid bilayer that confers viscoelastic behavior. Sialylated glycoproteins of the RBC membrane are responsible for a negatively charged surface, which creates a repulsive electric zeta potential (Z) between the cells.The compact layer of charge or Stern consists of ions
Publicado em: 2009
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35. PurificaÃÃo, caracterizaÃÃo e determinaÃÃo de atividade coagulante da lectina de sementes de Moringa oleifera
Moringa oleifera is a tropical plant of great economic importance with several industrial and medicinal applications. Many parts of the plant are used and the seed extract is commonly employed for water purification to human consumption. Lectins are proteins or glycoproteins of nonimmune origin, which bind carbohydrates bioespecifically with agglutinant cell
Publicado em: 2009
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36. HistoquÃmica com lectinas de sementes de Cratylia mollis analisando tecidos prostÃticos humanos
Prostate cancer is a malignant tumour of major incidence in elderly men in the developed countries and the second major cause of death for cancer. Lectins are proteins or glycoproteins, which recognize specifically and reversibly free or conjugated carbohydrates. They have been used in histochemistry to evaluate changes in the composition and expression of c
Publicado em: 2009