Toxic Metabolites
Mostrando 13-24 de 165 artigos, teses e dissertações.
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13. Validation of a High Performance Liquid Chromatography Method for Aflatoxins Determination in Corn Arepas
Aflatoxins are toxic metabolites produced by Aspergillus species in raw materials and foodstuffs from agricultural sources. Due to the fact that aflatoxins are potentially carcinogenetic, it is important to have reliable analytic methods that allow determining their levels in food matrices. The main aim of this investigation was to validate the method for af
J. Braz. Chem. Soc.. Publicado em: 2015-04
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14. Vitiligo - Part 1
Vitiligo is a chronic stigmatizing disease, already known for millennia, which mainly affects melanocytes from epidermis basal layer, leading to the development of hypochromic and achromic patches. Its estimated prevalence is 0.5% worldwide. The involvement of genetic factors controlling susceptibility to vitiligo has been studied over the last decades, and
An. Bras. Dermatol.. Publicado em: 2014-06
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15. Chemical constituents and technological functional properties of acerola (Malpighia emarginata DC.) waste flour
Acerola is a fruit that can be consumed in the form of juice and pulp. However, during its processing, a large amount of waste is generated (seed and bagasse). Adding value to these by-products is of great interest, since their use can enrich foods with nutrients and fiber. In this study, we performed phytochemical screening, determined the proximate and min
Food Sci. Technol. Publicado em: 01/10/2013
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16. Classes of secondary metabolites identified in three legume species
The objective of this study was to identify secondary metabolite classes of tropical kudzu, perennial soybean and archer legumes through identification by phytochemical screening and confirmation by infrared (IR), ¹H and carbon-13 NMR spectroscopy of fractions obtained by organic solvents partition of crude extracts. These analyses allowed for proposing the
R. Bras. Zootec.. Publicado em: 2013-10
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17. Pentacyclic triterpenes from Cecropia telenitida with immunomodulatory activity on dendritic cells
Pentacyclic triterpene Natural product Cytokine modulation Anti-inflammatory activity Dendritic cells Pentacyclic triterpenes are a large family of plant metabolites that exhibit a wide array of biological activities. The genus Cecropia,which encompasses many plant species, has been used as traditional medicine for the treatment of inflammatory diseases and
Rev. bras. farmacogn.. Publicado em: 2013-10
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18. Produção de carotenoides em culturas in vitro de Cleome rosea Vahl ex DC (Capparaceae) e avaliação de sua toxicidade e potencial antioxidante / Carotenoid production in vitro cultures of Cleome rosea Vahl ex DC (Capparaceae) and evaluation of toxicity and antioxidant potential.
The production and optimization of plants secondary metabolites with medicinal value have been achieved by using plant tissue culture techniques, which have showed great relevance when considering the conservation status of a species or their occurrence in degraded environments. The present study assessed the production of carotenoids in callus and cell susp
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/02/2012
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19. Antioxidant system response induced by aluminum in two rice cultivars
The antioxidant defense system response was evaluated in two rice cultivars (Oryza sativa L.), Fernandes (CNA-1158) and Maravilha (CNA-6843-1), treated with toxic levels of aluminum. After exposure to aluminum we determined plant growth, H2O2 and O2•- contents, lipid peroxidation, antioxidant enzymes activities and ascorbate and dehydroascorbate contents.
Braz. J. Plant Physiol.. Publicado em: 2012-06
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20. Toxic thermoresistant metabolites of Fusarium oxysporum are capable of inducing histopathological alterations in Wistar rats
The genus Fusarium is known to produce mycotoxins that cause fusariosis in plants, animals and humans. Mycotoxins are among the virulence factors of this genus. Metabolic extracts of Fusarium oxysporum, isolated from a patient with onychomycosis and sterilized by filtration or autoclave, were inoculated intradermally into Wistar rats at concentrations of 0.2
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2012
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21. Effect of Arrabidaea chica extracts on the Ehrlich solid tumor development
The aim of this study was to investigate the effect of Arrabidaea chica (Humb. & Bonpl.) B. Verl., Bignoniaceae, extracts on Ehrlich solid tumor development in Swiss mice. Leaves of A. chica were extracted with two distinct solvents, ethanol and water. The phytochemical analysis of the extracts indicated different classes of secondary metabolites like as ant
Revista Brasileira de Farmacognosia. Publicado em: 05/12/2011
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22. Evaluation of genetic damage induced by glyphosate isopropylamine salt using Tradescantia bioassays
Glyphosate is noted for being non-toxic in fishes, birds and mammals (including humans). Nevertheless, the degree of genotoxicity is seriously controversial. In this work, various concentrations of a glyphosate isopropylamine salt were tested using two methods of genotoxicity assaying, viz., the pink mutation assay with Tradescantia (4430) and the comet assa
Genetics and Molecular Biology. Publicado em: 03/12/2010
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23. Analysis of populational variation and characterization of secondary metabolites in the leaves of Lychnophora granmongolense (Duarte) Semir &Leitão Filho. / Análise de variação populacional e caracterização dos metabólitos secundários presentes nas folhas de Lychnophora granmongolense (Duarte) Semir &Leitão Filho
One of the main characteristics of plants of the Asteraceae family is their capacity to produce a huge diversity of secondary metabolites having therapeutic and toxic effects. An analytical method was developed based on HPLCDAD which was used to verify the existence of variations in Lychnophora granmongolense (Duarte) Semir &Leitão Filho secondary metabolit
Publicado em: 2010
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24. Nitric oxide induced alleviation of toxic effects of short term and long term Cd stress on growth, oxidative metabolism and Cd accumulation in Chickpea
The present study investigates the effect of long and short term Cd stress in chickpea plants and evaluates the protective effect of exogenous nitric oxide (NO) supplementation using sodium nitroprusside (SNP). Cadmium treatments were given before sowing (long term stress) and thirty days after germination (short term stress). Sodium nitroprusside was given
Brazilian Journal of Plant Physiology. Publicado em: 2010