Sickle Cell Anaemia
Mostrando 1-12 de 51 artigos, teses e dissertações.
-
1. Factors Predicting Heart Failure in Children Admitted to a Pediatric Emergency Ward in a Developing Country
Abstract Background Heart failure is an important cause of morbidity and mortality in children. Objective To determine the clinical characteristics of children with acute heart failure syndrome in the emergency ward of River state university teaching hospital, Nigeria and identify factors associated with poor outcomes. Methods This was an 18month retro
Int. J. Cardiovasc. Sci.. Publicado em: 2020-12
-
2. Cytotoxicity and DNA damage in the neutrophils of patients with sickle cell anaemia treated with hydroxyurea
A hidroxiuréia (HU) constitui o avanço mais importante no tratamento da anemia falciforme (AF) por prevenir complicações e aumentar a qualidade de vida dos pacientes. Entretanto, alguns aspectos do tratamento com HU permanecem obscuros, incluindo a sua ação e potencial toxicidade em outras células sanguíneas, tais como neutrófilos. Este estudo utili
Braz. J. Pharm. Sci.. Publicado em: 2014-04
-
3. Avaliação do programa de triagem neonatal de São José do Rio Preto no período de 2005 a 2007.
The neonatal screening is methodology populational specific screening if year old age from 0 to 30 days the of life that allow the early diagnostic of diseases like Congenital Hypothyroidism, Phenylketonuria, Sickle Cell Anaemia and others haemoglobinopathies as a preventive action and specific treatment to reduce or elimination of disorders associated to th
Publicado em: 2009
-
4. Perfil oxidativo e bioquímico em pacientes que apresentam anemia falciforme ou traço falciforme / Oxidative and biochemistry profile in sickle cell trait subjects and sickle cell anaemia patients
A Anemia Falciforme (AF) é uma doença autossômica recessiva e, dentre as hemoglobinopatias, é a mais comum das alterações hematológicas hereditárias conhecidas no homem. Sua distribuição é ampla, abrangendo todos os continentes. AF foi a primeira doença caracterizada em nível molecular. É causada por uma mutação no gene beta da globina, produ
Publicado em: 2008
-
5. Diagnóstico de hipertensão pulmonar em indivíduos adultos com doença falciforme / Diagnosis of pulmonary hypertension in adults with sickle cell disease
INTRODUCTION: Patients with sickle cell disease (SCD) and other haemolytic anaemia have increased prevalence of pulmonary hypertension (PH) that is related to higher mortality. The aim of this stdy was to determine the prevalence of PH and, its clinical, laboratorial and hemodynamic features. METHODS: In a crosssectional study, we evaluated 80 consecutive pa
Publicado em: 2008
-
6. O campo da anemia falciforme e a informação genética : um estudo sobre o aconselhamento genético
Esta dissertação teve como objeto de estudo a prática do aconselhamento genético, procedimento biomédico por meio do qual as pessoas são informadas sobre traços e doenças genéticas e orientadas com relação às decisões reprodutivas. O aconselhamento genético é um caso singular para a análise da composição de um campo como proposto na teoria
Publicado em: 2006
-
7. Efeito de flavonoides no eritrocito de individuos normais e portadores de anemia falciforme
Oxygen reactive species (ROS) are constantly formed in aerobic cells, particularly in the mithocondria and erythrocytes. These ROS, under normal conditions, are removed by an efficient antioxidant system composed by antioxidant enzymes, glutathione, vitamines and microelements. However, when the ROS production is higher than the antioxidant system capacity,
Publicado em: 2002
-
8. A rapid whole blood solubility test to differentiate the sickle-cell trait from sickle-cell anaemia
A simple and rapid screening test which differentiates sickle-cell trait and sickle-cell anaemia is described. The test utilizes 0·1 ml of whole blood and is based on the low solubility of reduced sickle haemoglobin. Results intermediate between the sickle-cell trait and sickle-cell anaemia are obtained in unusual cases of sickle-cell anaemia with high foet
-
9. Studies on iron metabolism in sickle cell anaemia, sickle cell haemoglobin C disease, and haemoglobin C disease using a large volume liquid scintillation counter
Iron absorption as measured by a faecal recovery method in young adult males living in a tropical zone was high, even in the absence of anaemia. There was an inverse relation between the iron absorption and the packed cell volume. The highest absorption was found in sickle cell anaemia patients, where the packed cell volume is the lowest. The incorporation o
-
10. Sickle cell anaemia and the NBT test
Patients with sickle cell anaemia have an increased susceptibility to bacterial infections Previous reports of false-negative nitro blue tetrazolium (NBT) tests in the presence of bacteria infection and of a faulty phagocytic response following stimulation in vitro have suggested the possibility of polymorphonuclear dysfunction in certain patients with sickl
-
11. Bronchopulmonary anastomoses in sickle-cell anaemia
Histological details are given of bronchopulmonary anastomoses in a patient who died suddenly and was known to have sickle-cell anaemia.
-
12. Changing blood picture in sickle-cell anaemia from shortly after birth to adolescence.
The blood picture of children with sickle-cell anaemia was found to change with age. The changes were most marked in the first year but the mean level of haemoglobin, haemoglobin F, and target cells fell until adolescence, and irreversibly sickled cells rose. Reticulocytes, Howell Jolly bodies, and normablasts altered little after one year. The fall in haemo