A rapid whole blood solubility test to differentiate the sickle-cell trait from sickle-cell anaemia
AUTOR(ES)
Huntsman, R. G.
RESUMO
A simple and rapid screening test which differentiates sickle-cell trait and sickle-cell anaemia is described. The test utilizes 0·1 ml of whole blood and is based on the low solubility of reduced sickle haemoglobin. Results intermediate between the sickle-cell trait and sickle-cell anaemia are obtained in unusual cases of sickle-cell anaemia with high foetal haemoglobin.