Sickle Cell Anaemia
Mostrando 13-24 de 51 artigos, teses e dissertações.
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13. Anaemic crisis in sickle cell disease.
Sixteen episodes of acute anaemia necessitating urgent blood transfusion have been investigated in 13 children with sickle cell anaemia. In five out of seven episodes there was evidence of increased haemolysis while in 10 out of 16 episodes a profound fall in reticulocyte count indicated marrow erythroid cell failure. Cold agglutinins active at room temperat
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14. Spontaneous peripheral chorioretinal neovascularisation in association with sickle cell anaemia.
Chorioretinal neovascularisation was noted in the midperipheral fundus of a young black girl with sickle cell anaemia. Rapid-sequence fluorescein angiography showed choroidally fed neovascularisation in the centre of a large black sunburst (chorioretinal scar). We suspect that a massive midperipheral retinal haemorrhage from the sickle cell disease caused th
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15. Large cerebral vessel disease in sickle cell anaemia.
An 18 year old male with documented sickle cell disease was admitted to the hospital for the final time in coma. Cerebral angiography revealed multiple stenotic lesions of the large cerebral vessels. The pathology of this large vessel involvement is demonstrated and the potential contribution of large as opposed to small cerebral vessel disease in the neurol
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16. Decline in hepatitis B infection in sickle cell anaemia and beta thalassaemia major.
Seventy five Saudi children, 55 with sickle cell anaemia and 20 with beta thalassaemia major, who were negative for all hepatitis B virus (HBV) markers five years ago were recently investigated for exposure to HBV and hepatitis C virus (HCV) infection. Of the 55 patients with sickle cell anaemia and 20 with beta thalassaemia major, 20 and five patients respe
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17. Hepatic abscess in sickle cell anaemia: a rare manifestation.
A child with sickle cell anaemia developed a hepatic abscess, which was managed successfully by percutaneous drainage under ultrasound control. A history of attacks of pain dissimilar to usual vaso-occlusive crises should be treated with suspicion and investigated appropriately.
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18. The Pathology of Sickle Cell Haemoglobin C Disease and Sickle Cell Anaemia
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19. Heterogeneity of sickle cell anaemia in Arabs: review of cases with various amounts of fetal haemoglobin.
A study is presented on eleven patients with homozygous sickle cell anaemia. They are non-Sheeah Arabs from the United Arab Emirates on the south-eastern coast of the Arabian Peninsula. The proportions of fetal haemoglobin in these patients are variable, and there is a marked variation in the severity of their disease condition; these facts are not related.
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20. An automated screening technique for the detection of sickle-cell haemoglobin
An automated technique is described which is capable of detecting sickle-cell haemoglobin and differentiating the sickle-cell trait from sickle-cell anaemia. The method is based upon the Itano solubility test and utilizes Technicon equipment.
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21. Vascular occlusion and infarction in sickle cell crisis and the sickle chest syndrome.
A young adult with homozygous sickle cell anaemia (Hb SS) suffered a fatal sickle cell crisis complicated by the sickle chest syndrome. At necropsy multiple large infarcts of the lung, bone marrow, and pituitary gland were found. The large majority of pulmonary infarcts were not associated with either gross or microscopic vaso-occlusion. These findings are d
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22. Sickle cell disease associated with uric acid deposition disease.
The infrequent occurrence of gout in patients with sickle cell anaemia contrast with the high incidence of hyperuricaemia and impaired renal function. This report records the third case of synovial membrane uric acid deposition and the first case of tophaceous deposits in haemoglobin SS patients. The limitations of a diagnosis of gout on the basis of hyperur
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23. Studies on the blood lipids and lipoproteins in thalassaemia and sickle cell anaemia
In Cooley's anaemia the serum lipid fraction, determined by chemical analysis, was found to be decreased. The lipoprotein distribution by paper electrophoresis showed a characteristic pattern with abnormally low α1 fraction and high concentrations of the β fractions. There is no relationship between age and serum lipoprotein distribution. A correlation was
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24. Mild sickle-cell anaemia in Iran associated with high levels of fetal haemoglobin.
Sixteen subjects, with sickle-cell anaemia, all Iranians (ages 3 to 56 years), with very mild symptomatology are reported. Some of the subjects had been totally asymptomatic. Splenomegaly was noted in 9 cases. There was an increase in the mean level of fetal haemoglobin (18%); this is the probable explanation for the mild phenotype. In 29 subjects with sickl