Novel Object Recognition
Mostrando 1-12 de 16 artigos, teses e dissertações.
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1. Memory impairments and increased GFAP expression in hippocampal astrocytes following hypercaloric diet in rats
RESUMO Objetivo: A inflamação hipotalâmica e a superexpressão da proteína glial fibrilar ácida (GFAP) em astrócitos são bem descritas em animais obesos, assim como déficits cognitivos e de memória. Como o hipocampo desempenha importante papel na consolidação de informações, esta investigação teve como objetivo observar a função da memória
Arq. Neuro-Psiquiatr.. Publicado em: 23/09/2019
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2. Hypericum perforatum chronic treatment affects cognitive parameters and brain neurotrophic factor levels
Objective: To evaluate the effects of Hypericum perforatum (hypericum) on cognitive behavior and neurotrophic factor levels in the brain of male and female rats. Methods: Male and female Wistar rats were treated with hypericum or water during 28 days by gavage. The animals were then subjected to the open-field test, novel object recognition and step-down i
Rev. Bras. Psiquiatr.. Publicado em: 09/08/2018
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3. Is Forced Swimming Immobility a Good Endpoint for Modeling Negative Symptoms of Schizophrenia? - Study of Sub-Anesthetic Ketamine Repeated Administration Effects
ABSTRACT Immobility time in the forced swimming has been described as analogous to emotional blunting or apathy and has been used for characterizing schizophrenia animal models. Several clinical studies support the use of NMDA receptor antagonists to model schizophrenia in rodents. Some works describe the effects of ketamine on immobility behavior but there
An. Acad. Bras. Ciênc.. Publicado em: 17/08/2017
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4. Effect of alpha-7 nicotinic acetylcholine receptor activation on beta-amyloid induced recognition memory impairment. Possible role of neurovascular function
PURPOSE: To evaluate the effects of PHA-543613 (α7-nAChR agonist) and galantamine (acetylcholinesterase inhibitor (AChEI)) on recognition memory and neurovascular coupling (NVC) response in beta-amyloid (Aβ) 25-35-treated mice. METHODS: PHA-543613 (1 mg/kg, i.p.), and galantamine (3 mg/kg, s.c.), effects were tested in Aβ25-35 mice model of AD. α7-nA
Acta Cir. Bras.. Publicado em: 2015-11
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5. Efeito do Butirato de sódio sobre o déficit de memória induzido pela sobrecarga neonatal com ferro
Iron accumulation in the brain has been associated to the pathogenesis of neurodegenerative disorders. We have previously demonstrated that iron overload in the neonatal period results in severe and persistent memory deficits in adult rats. Here, using the animal model of cognitive impairment induced by iron overload we tested the effects of NaBut in amelior
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/03/2011
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6. Avaliação pré-clínica de atividades biológicas de moléculas de Mangifera indica e de Valeriana glechomifolia
Neste estudo avaliamos atividades biológicas pré-clínicas de moléculas obtidas de Mangifera indica e de Valeriana glechomifolia. Mangiferina, isolada de M. indica, estimulou a proliferação celular e induziu um aumento significativo na secreção do fator de crescimento do nervo e do fator de necrose tumoral em células de glioblastoma humano U138-MG in
Publicado em: 2011
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7. Método de reconhecimento da marcha humana por meio da fusão das características do movimento global / Recognition method of human gait by fusion of features of the global movement
This paper proposes a novel computer vision approach that processes video sequences of people walking and then recognises those people by their gait. Human motion carries different information that can be analysed in various ways. The skeleton carries motion information about human joints, and the silhouette carries information about boundary motion of the h
Publicado em: 2010
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8. Evaluation of two experimental models of hepatic encephalopathy in rats
The serious neuropsychological repercussions of hepatic encephalopathy have led to the creation of several experimental models in order to better understand the pathogenesis of the disease. In the present investigation, two possible causes of hepatic encephalopathy, cholestasis and portal hypertension, were chosen to study the behavioral impairments caused b
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-01
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9. A cognitive map for object memory in the hippocampus
The hippocampus has been proposed to support a cognitive map, a mental representation of the spatial layout of an environment as well as the nonspatial items encountered in that environment. In the present study, we recorded simultaneously from 43 to 61 hippocampal pyramidal cells as rats performed an object recognition memory task in which novel and repeate
Cold Spring Harbor Laboratory Press.
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10. Recognition Memory for Complex Visual Discriminations Is Influenced by Stimulus Interference in Rodents With Perirhinal Cortex Damage
Rats with perirhinal cortex (PRC), hippocampal, or sham lesions were trained on a successive discrimination go/no-go task to examine recognition memory for an array of visual objects with varying interference among the objects in the array. Rats were trained to recognize a target array consisting of four particular objects that could be presented in any one
Cold Spring Harbor Laboratory Press.
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11. A Neural Circuit Analysis of Visual Recognition Memory: Role of Perirhinal, Medial, and Lateral Entorhinal Cortex
Using a continuous recognition memory procedure for visual object information, we sequentially presented rats with eight novel objects and four repeated objects (chosen from the 8). These were selected from 120 different three-dimensional objects of varying sizes, shapes, textures, and degree of brightness. Repeated objects had lags ranging from 0 to 4 (from
Cold Spring Harbor Laboratory Press.
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12. Effects of Stress and Hippocampal NMDA Receptor Antagonism on Recognition Memory in Rats
Exposures to uncontrollable stress have been shown to alter ensuing synaptic plasticity in the hippocampus and interfere with hippocampal-dependent spatial memory in rats. The present study examined whether stress, which impairs hippocampal long-term potentiation (LTP), also affects (nonspatial) hippocampal-dependent object-recognition memory, as tested on t
Cold Spring Harbor Laboratory Press.