Molecular Cytogenetics
Mostrando 1-12 de 88 artigos, teses e dissertações.
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1. Cytogenetics and DNA barcode reveal an undescribed Apareiodon species (Characiformes: Parodontidae)
Abstract Parodontidae is a small group of fish and some species are particularly difficult to identify due to the lack of sufficiently consistent morphological traits. Cytogenetically, the species possess 2n = 54 chromosomes and are either sex-homomorphic or sex-heteromorphic (regarding its chromosomes). We evaluated data on color, tooth morphology, cytogene
Genet. Mol. Biol.. Publicado em: 27/06/2019
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2. Pre-analytical parameters associated with unsuccessful karyotyping in myeloid neoplasm: a study of 421 samples
Cytogenetics is essential in myeloid neoplasms (MN) and pre-analytical variables are important for karyotyping. We assessed the relationship between pre-analytical variables (time from collection to sample processing, material type, sample cellularity, and diagnosis) and failures of karyotyping. Bone marrow (BM, n=352) and peripheral blood (PB, n=69) samples
Braz J Med Biol Res. Publicado em: 14/02/2019
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3. Contributions to the systematic of Pimelodidae (Osteichthyes, Siluriformes): basic and molecular cytogenetics on seven species of Pimelodus from three Brazilian hydrographic systems
RESUMO Pimelodidae abriga várias espécies e é amplamente distribuída ao longo da região Neotropical. Pimelodus é o gênero com o maior número de espécies, porém é um grupo polifilético. Análises citogenéticas foram realizadas em menos da metade das espécies válidas. Aqui, sete espécies de Pimelodus de três sistemas hidrográficos brasileiros
Neotrop. ichthyol.. Publicado em: 25/06/2018
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4. Protocol for chromosome-specific probe construction using PRINS, micromanipulation and DOP-PCR techniques
ABSTRACT Chromosome-specific probes have been widely used in molecular cytogenetics, being obtained with different methods. In this study, a reproducible protocol for construction of chromosome-specific probes is proposed which associates in situ amplification (PRINS), micromanipulation and degenerate oligonucleotide-primed PCR (DOP-PCR). Human lymphocyte cu
An. Acad. Bras. Ciênc.. Publicado em: 07/12/2017
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5. Cytogenetics and Molecular Genetic Analysis of Chimerism in Marmosets (Callithrix: Primates)
ABSTRACT The birth of fraternal twins is a characteristic frequently observed in callitrichids. Cytogenetic studies have demonstrated hematopoietic chimerism in marmosets with the occurrence of two cell lines 2n=46,XX/46,XY in females and males co-twins, without phenotypic changes. Amplification by PCR have also been used to verify the presence of the SRY ge
An. Acad. Bras. Ciênc.. Publicado em: 2017-12
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6. Identification of the MYST3-CREBBP fusion gene in infants with acute myeloid leukemia and hemophagocytosis
ABSTRACT Background: Acute myeloid leukemia presenting the MYST3-CREBBP fusion gene is a rare subgroup associated with hemophagocytosis in early infancy and monocytic differentiation. The aim of this study was to define the relevant molecular cytogenetic characteristics of a unique series of early infancy acute myeloid leukemia cases (≤24 months old), bas
Rev. Bras. Hematol. Hemoter.. Publicado em: 2016-12
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7. Human molecular cytogenetics: from cells to nucleotides
The field of cytogenetics has focused on studying the number, structure, function and origin of chromosomal abnormalities and the evolution of chromosomes. The development of fluorescent molecules that either directly or via an intermediate molecule bind to DNA has led to the development of fluorescent in situ hybridization (FISH), a technology linking cytog
Genet. Mol. Biol.. Publicado em: 2014
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8. Molecular analysis of holoprosencephaly in South America
Holoprosencephaly (HPE) is a spectrum of brain and facial malformations primarily reflecting genetic factors, such as chromosomal abnormalities and gene mutations. Here, we present a clinical and molecular analysis of 195 probands with HPE or microforms; approximately 72% of the patients were derived from the Latin American Collaborative Study of Congenital
Genet. Mol. Biol.. Publicado em: 2014
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9. Diversidade em Psidium guajava L. por caracteres morfológicos, moleculares e citogenéticos / Diversity in Psidium guajava L. by morphological, molecular and cytogenetics
Guava (Psidium guajava L.) is one of the most economically important fruit crop from Myrtaceae family. Brazil is one of the largest producers of guava in the world, which is a potential crop in growth and profitability. Cross-pollination of the species and the existence of heterogeneous seminal propagation orchards result in variability, allowing the selecti
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/07/2012
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10. Contribuições para o estabelecimento de estratégias laboratoriais em genética para a saúde pública no Brasil utilizando a síndrome de deleção 22q11.2 como modelo / Contributions to the establishment of laboratory strategies in medical genetics for public health in Brazil, using the 22q11.2 deletion syndrome as a model
The introduction of new technologies of molecular diagnosis for health care has been a challenge in the last years, especially in Brazil, where the majority of the population is served by the public health system. The 22q11.1 deletion syndrome is the most common syndrome that has palatal anomalies as a major feature, with a prevalence of 1/4000 births. Consi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/02/2012
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11. Estudos citogenéticos em peixes das famílias Heptapteridae e Pseudopimelodidae (Siluriformes)
As famílias Heptapteridae e Pseudopimelodidae, da ordem Siluriformes, são compostas por peixes de couro endêmicos da região Neotropical. A família Heptapteridae é composta por 24 gêneros e 189 espécies válidas e Pseudopimelodidae por 5 gêneros e 29 espécies descritas. Estudos citogenéticos nessas duas famílias ainda são escassos, principalmente
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2012
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12. ASPECTOS EVOLUTIVOS E DIFERENCIAÇÃO DE POPULAÇÕES DE Astyanax scabripinnis (CHARACIDAE, INCERTAE SEDIS)
The species complex Astyanax scabripinnis are composed by fish with wide geographic distribution. Their populations are often isolated in small streams, separated by thousands of years, making it a very interesting system to study evolution. The use of different markers is crucial, since they allow inferences on the identification of individuals and therefor
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/02/2012