Hereditary Thrombophilia
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. Prevalence of thrombophilia-associated genetic risk factors in blood donors of a regional hospital in southern Brazil
ABSTRACT Introduction: Thromboembolic events occur due to an imbalance in the hemostasis and some factors associated with this condition can be inherited. In order to evaluate the frequency of genotypes considered to be common hereditary risk factors for thrombophilia associated with venous thrombosis (g.1691G>A and g.20210G>A) and hyperhomocysteinemia (g.6
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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2. Manejo obstétrico de la deficiencia hereditaria de antitrombina durante el embarazo y puerperio. Dos casos clínicos
Abstract Introduction: hereditary antithrombin III deficiency is a rare disease that affects 0.02-0.2% of the population. It may be associated with a higher rate of complications and adverse outcomes in both mother and fetus. The present study describes the management of a woman with antithrombin III deficiency and two consecutive pregnancies. Description:
Rev. Bras. Saude Mater. Infant.. Publicado em: 2015-12
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3. Associação entre a presença de trombofilias adquiridas e hereditárias e a ocorrência de abortamentos recorrentes, perdas fetais em gestantes de alto risco / Association between the presence of acquired and inherited thrombophilia and the occurrence of miscarriage, fetal loss in pregnant women at high risk
The presence of thrombophilia has been associated with most maternal venous thrombotic events and adverse complications of pregnancy. To check for association between the occurrence of miscarriage, fetal loss with the presence of hereditary and acquired thrombophilia study was performed involving 180 pregnant women divided into two groups, group AB - women w
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/02/2010
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4. Trombose venosa cerebral: evolução clínica e fatores prognósticos em 111 pacientes / Cererbal venous thrombosis: clinical outcome and prognostic factors in 111 patients
Introduction: The cerebral venous thrombosis (CVT) clinical evolution is quite variable from complete recovery to death. Some European series and a multicenter study had identified prognostic factors related to CVT prognosis. The identification of these factors is important for the best therapeutic decision to patients. This study aims to identify the progno
Publicado em: 2008
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5. AlteraÃÃo bioquÃmica em fator de coagulaÃÃo como causa de trombose venosa profunda â relato de caso clÃnico
Deep venous thrombosis (DVT) in the pediatric population (0-18 year old) has been reported as lower than in adults. In almost half of the children, three or four risk factors for thrombosis are present simultaneously. Even in children with thromboembolic disturbance, thrombosis did not occur spontaneously; the hemostatic defect became apparent because thromb
Publicado em: 2006
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6. Prevalence of hereditary risk factors for thrombophilia in Belém, Brazilian Amazon
Different risk factors for venous thromboembolism (VTE) have been identified, including hereditary abnormalities in the mechanisms of coagulation and fibrinolysis. We investigated five genetic polymorphisms (FVL G1691A, FII G20210A, MTHFR C677T, TAFI A152G and TAFI T1053C) associated with VTE in individuals from the city of Belém in the Brazilian Amazon who
Genetics and Molecular Biology. Publicado em: 2006
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7. Defeito bioquÃmico em fator V, fator V de Leiden, em paciente jovem com trombose venosa profunda: estudo de caso
Inherited disturbances of the coagulation and fibrinolysis have been associated with thrombophilia. Trauma can be a precipitant of the deep vein thrombosis (DVT) in Factor V Leiden (FVL) carriers, the most common polymorphism cause of hereditary thrombophilia. The objective of this study was to analyze the case of a 15 years old boy, his parents and a contro
Publicado em: 2001
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8. Hereditary thrombophilia: identification of nonsense and missense mutations in the protein C gene.
The structure of the gene for protein C, an anticoagulant serine protease, was analyzed in 29 unrelated patients with hereditary thrombophilia and protein C deficiency. Gene deletion(s) or gross rearrangement(s) was not demonstrable by Southern blot hybridization to cDNA probes. However, two unrelated patients showed a variant restriction pattern after Pvu I
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9. Prevalence of the factor V Leiden mutation in hepatic and portal vein thrombosis.
BACKGROUND: The factor V Leiden (FVL) mutation has been shown to be the most frequent cause of hereditary thrombophilia. The prevalence of the mutation in patients with Budd-Chiari syndrome (BCS) and portal vein thrombosis (PVT) has not been fully elucidated. AIMS: To investigate the association between the FVL mutation and BCS and PVT. PATIENTS: Thirty pati