Drug Effects
Mostrando 1-12 de 2893 artigos, teses e dissertações.
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1. Deve-se retirar a sulfonilureia quando for iniciada a insulina em pacientes com diabetes tipo 2 usando metformina e sulfonilureia em doses máximas e sem controle glicêmico adequado?
Não é necessário retirar a sulfonilureia ao iniciar insulina NPH em pacientes com diabetes tipo 2. A manutenção do uso da sulfonilureia durante o início do tratamento com insulina NPH (insulina basal) está associada ao uso de doses 30% menores de insulina, menor risco de hipoglicemias e menor ganho de peso.
Deve-se suspender a sulfonilureia e
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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2. Como deve ser feita a inibição da lactação?
Métodos não farmacológicos:
– Evitar a sucção e outras formas de estímulo.
– Aplicar compressas frias durante 10 minutos, 4 vezes ao dia.
– Fazer enfaixamento compressivo, com ataduras elásticas por volta de 7 a 10 dias após o parto, com cuidado para não restringir os movimentos respiratórios ou causar desconforto materno
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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3. É sempre necessário solicitar um eletrocardiograma antes de prescrever um antidepressivo tricíclico?
Não há necessidade absoluta de solicitar eletrocardiograma (ECG) antes de prescrever um antidepressivo tricíclico. Pacientes sem fatores de risco para morte súbita e em uso de doses baixas de tricíclicos (abaixo de 100 mg/dia de amitriptilina, imipramina e clomipramina e abaixo de 62,5 mg/dia de nortriptilina,) não necessitam realizar um ECG antes d
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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4. É necessário fazer ecografia após colocação de DIU para confirmação de posicionamento?
Não é necessário fazer ecografia transvaginal de rotina para confirmar posicionamento após colocação de dispositivo intrauterino (DIU). As mulheres devem ser orientadas a retornar para avaliação caso percebam febre, dor abdominal, piora da dor pélvica, síncope, sangramento uterino excessivo, suspeita de expulsão do dispositivo, leucorreia malch
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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5. Bradycardia in a pediatric population after sugammadex administration: case series
Abstract Sugammadex is a distinctive neuromuscular reversal drug that acts by encapsulating the neuromuscular relaxant molecule and dislodging it from its site of action. Sugammadex has been approved for pediatric patients over 2 years of age. Although arrhythmias have been reported, there is no report of adverse effects in healthy children, such as severe b
Brazilian Journal of Anesthesiology. Publicado em: 2023
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6. Adverse effects associated with favipiravir in patients with COVID-19 pneumonia: a retrospective study
ABSTRACT BACKGROUND: Favipiravir is generally used in treating coronavirus disease 2019 (COVID-19) pneumonia in Turkey. OBJECTIVE: To determine the side effects of favipiravir and whether it is a good treatment option. DESIGN AND SETTING: Retrospective study conducted in Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara, Tur
Sao Paulo Medical Journal. Publicado em: 2022
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7. Long-term consequences of osteoporosis therapy with denosumab
ABSTRACT Denosumab (DMAb) is a human monoclonal antibody used as an antiresorptive drug in the treatment of osteoporosis. Approval at a dosage of 60 mg every 6 months was based on the results of the randomized, placebo-controlled trial (FREEDOM). The design of this 3-year study included an extension for up to 10 years. Those who were randomized to DMAb conti
Archives of Endocrinology and Metabolism. Publicado em: 2022
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8. Does mismatch negativity have utility for NMDA receptor drug development in depression?
Rapid antidepressant effects associated with ketamine have shifted the landscape for the development of therapeutics to treat major depressive disorder (MDD) from a monoaminergic to glutamatergic model. Treatment with ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, may be effective, but has many non-glutamatergic targets, and clinical and logis
Brazilian Journal of Psychiatry. Publicado em: 2022
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9. Drug utilization study in neonatal intensive care unit at tertiary care hospital
SUMMARY OBJECTIVE: Neonates are more susceptible to drug interactions and adverse effects, and special care should be taken when prescribing medication to them. This study aimed to investigate drug usage in the neonatal intensive care unit of a tertiary care hospital. METHODS: This prospective observational study was conducted on 98 patients at the Apollo
Revista da Associação Médica Brasileira. Publicado em: 2022
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10. Vitamin C (Ascorbic acid) protects from neuropathy caused by cisplatin, through enhanced heat shock protein-70 and reduced oxidant effect
SUMMARY OBJECTIVE: We aimed to determine whether vitamin C has a protective effect on cisplatin-induced neuropathy in rats. METHODS: In total, 24 rats were included in the study of which 8 rats (no drug administered) were categorized as the control group. The remaining 16 rats were given a total dose of 20 mg/kg cisplatin to induce neuropathy. These drug-a
Revista da Associação Médica Brasileira. Publicado em: 2022
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11. Rapamycin and Paclitaxel Affect Human Aortic Smooth Muscle Cells-Derived Foam Cells Viability and Proliferation
Abstract Introduction: Drug-eluting stents (DES) coated with rapamycin or paclitaxel as antiproliferative substances significantly reduced the incidence of clinical restenosis and had fewer side effects after percutaneous coronary intervention. However, DES coated with rapamycin or paclitaxel still cause restenosis due to abnormal tissue growth which remain
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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12. Anabolic therapy for osteoporosis: update on efficacy and safety
ABSTRACT Anabolic agents for the treatment of osteoporosis increase bone density, improve bone strength, and reduce fracture risk. They are distinguished from antiresorptive drugs by their property of increasing osteoblastic bone formation. Teriparatide and abaloparatide are parathyroid hormone receptor agonists that increase bone remodeling with bone format
Archives of Endocrinology and Metabolism. Publicado em: 2022