Drug Effects
Mostrando 13-24 de 2893 artigos, teses e dissertações.
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13. Comparative Study of Some Numerical Schemes for a Fractional Order Model of HIV Infection Treatment
ABSTRACT A fractional order mathematical model that already exists in the literature, was considered. This model was established to study the effects of medicinal treatment in people infected with the human immunodeficiency virus (HIV). The importance of this study is that the model evaluates, among other parameters, the density of healthy and HIV-infected C
Trends in Computational and Applied Mathematics. Publicado em: 2022
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14. Effect of two oral formulations of cannabidiol on responses to emotional stimuli in healthy human volunteers: pharmaceutical vehicle matters
Objective: To compare plasma concentrations of cannabidiol (CBD) following oral administration of two formulations of the drug (powder and dissolved in oil), and to evaluate the effects of these distinct formulations on responses to emotional stimuli in healthy human volunteers. Methods: In a randomized, double-blind, placebo-controlled, parallel-group desi
Brazilian Journal of Psychiatry. Publicado em: 2022
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15. Multimodal Neuromonitoring During Pediatric Cardiac Surgery
Abstract Introduction: Neuromonitoring (electroencephalogram [EEG] and cerebral oximetry) is essential for appropriate anesthesia and neuroprotection assessment during pediatric cardiac surgery. Methods: We describe the intraoperative pediatric multimodal and multiparametric neuromonitoring pattern of the software system Neuron-Spectrum (Kandel®) that con
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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16. Effects of Social Skills Training for Drug Users under Treatment
Resumo O Treinamento em Habilidades Sociais (THS) apresenta resultados satisfatórios em populações clínicas e não clínicas. Objetiva-se avaliar os efeitos do THS na percepção de qualidade de vida e habilidades sociais de usuários de substâncias em tratamento nas condições de pós-intervenção e follow-up. Trata-se de um estudo quase-experimental
Psico-USF. Publicado em: 2022
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17. The effects of macronutrients composition on hormones and substrates during a meal tolerance test in drug-naive and sitagliptin-treated individuals with type 2 diabetes: a randomized crossover study
ABSTRACT Objectives: To evaluate the effect of sitagliptin treatment in early type 2 diabetes mellitus (T2DM) and the impact of different macronutrient compositions on hormones and substrates during meal tolerance tests (MTT). Materials and methods: Half of the drug-naive patients with T2DM were randomly assigned for treatment with 100 mg of sitagliptin, q
Archives of Endocrinology and Metabolism. Publicado em: 2022
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18. Long-term effects of antipsychotics on mortality in patients with schizophrenia: a systematic review and meta-analysis
Objective: To gather current evidence on the impact of antipsychotics on long-term mortality in patients with schizophrenia. Methods: We systematically searched for articles in Embase, PubMed, and PsycINFO reporting the long-term mortality (follow-up > 1 year) of patients with schizophrenia who were using any antipsychotics. We then conducted multiple meta-
Brazilian Journal of Psychiatry. Publicado em: 2022
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19. Evaluation of the efficacy, safety, and side effects of secukinumab in patients with moderate-to-severe psoriasis: real-world data from a retrospective multicenter study
Abstract Background: Clinical studies have demonstrated that IL-17A inhibition with secukinumab is effective for clearing the skin of patients with psoriasis and has a favorable safety profile. Objective: The authors aim to determine whether secukinumab is effective and safe for the treatment of moderate-to-severe chronic psoriasis based on clinical experi
Anais Brasileiros de Dermatologia. Publicado em: 2022
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20. The Application of P300-Long-Latency Auditory-Evoked Potential in Parkinson Disease
Abstract Introduction Parkinson disease (PD) is a degenerative and progressive neurological disorder characterized by resting tremor, stiffness, bradykinesia, and postural instability. Despite the motor symptoms, PD patients also consistently show cognitive impairment or executive dysfunction. The auditory event-related potential P300 has been described as
International Archives of Otorhinolaryngology. Publicado em: 2022
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21. Tocilizumab is useful for coronavirus disease 2019 patients: the key point is timing
SUMMARY OBJECTIVE: In coronavirus disease 2019, a rapidly progressive inflammatory process is considered to be the main cause of organ damage and mortality. Therefore, the importance of anti-inflammatory treatments such as tocilizumab is increasing. METHODS: A total of 107 patients who received tocilizumab between March 2020 and March 2021 were included in
Revista da Associação Médica Brasileira. Publicado em: 2022
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22. Ultrasound-guided erector spinae plane block for open inguinal hernia repair: a randomized controlled trial
Abstract Background and objectives: Inguinal hernia repair is associated with significant postoperative pain. We assessed the analgesia efficacy of unilateral Erector Spinae Plane block (ESP) performed under ultrasound guidance in patients submitted to open unilateral inguinal hernia repair, comparing ESP to spinal anesthesia administered with or without op
Brazilian Journal of Anesthesiology. Publicado em: 2022
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23. Which is the best way of using nitrous oxide for treatment and research in neuropsychiatry?
Objective: Whether for spiritual, recreational, or potential therapeutic use, interest in ayahuasca has grown remarkably. Ayahuasca’s main active substances are N,N‐dimethyltryptamine and certain monoamine oxidase inhibitor β-carbolines. Possible drug interactions are a major concern, and research is lacking in this area. The objective of this study wa
Braz. J. Psychiatry. Publicado em: 2021-08
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24. Risk assessment of ayahuasca use in a religious context: self-reported risk factors and adverse effects
Objective: Whether for spiritual, recreational, or potential therapeutic use, interest in ayahuasca has grown remarkably. Ayahuasca’s main active substances are N,N‐dimethyltryptamine and certain monoamine oxidase inhibitor β-carbolines. Possible drug interactions are a major concern, and research is lacking in this area. The objective of this study wa
Braz. J. Psychiatry. Publicado em: 2021-08