Biliary Atresia
Mostrando 13-24 de 42 artigos, teses e dissertações.
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13. Immunohistochemical studies of stellate cells in experimental cholestasis in newborn and adult rats
BACKGROUND AND AIMS: Although there is much known about liver diseases, some aspects remain unclear, such as the nature of the differences between the diseases observed in newborn infants and those in adults. For example, how do newborns respond to duct epithelial cell injury? Do the stellate cells in newborns respond similarly to those in adults during bili
Clinics. Publicado em: 2008
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14. Atresia das vias biliares extra-hepáticas: conhecimentos atuais e perspectivas futuras
OBJETIVOS: Apresentar uma revisão atualizada sobre atresia das vias biliares extra-hepáticas, com ênfase em etiopatogenia, abordagens diagnósticas e terapêuticas e prognóstico. FONTES DOS DADOS: Foram selecionadas pelos sites de busca médica (MEDLINE e PubMed) pesquisas relacionadas à atresia biliar, utilizando as seguintes palavras-chave: biliary at
Jornal de Pediatria. Publicado em: 2007-04
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15. Transplante hepático pediátrico: experiência do Hospital das Clínicas da UFMG
Objectives: To evaluate the experience of the division of liver transplantation of the Alfa Institute of HC/UFMG, over the first ten years. Method: Descriptive study, through retrospective analysis of 84 children and adolescents enrolled in liver transplantation waiting list of HC/UFMG, from March 1995 to January 2006, by the following facts: age, sex, blood
Publicado em: 2007
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16. Fatores preditivos clínicos e laboratoriais de varizes esofágicas em crianças e adolescente com síndrome de hipertensão porta.
The objective of this study is to determine the clinical and laboratory parameters that could help predict the presence of esophageal varices in children and adolescents with portal hypertension syndrome. All 111 children and adolescents with portal hypertension syndrome without previous history of upper gastrointestinal bleeds admitted to the Outpatient Ped
Publicado em: 2006
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17. Portal and periportal fibrosis in experimental extra-hepatic biliary obstruction in young and adult rats: contribution to biliary atresia study / "Fibrose portal e periportal na obstrução extra-hepática experimental em ratos jovens e adultos: contribuição para o estudo da atresia das vias biliares"
Biliary atresia is an hepatic disease of infancy. Etiology is unknown, and diagnosis is made by liver biopsy, with ductular proliferation being the main histological feature. Bile duct ligation in rats is an useful experimental model of biliary obstruction. The aim of this study of extra-hepatic cholestasis was analyse hepatic histological alterations in you
Publicado em: 2003
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18. Detecção do citomegalovirus em fragmento hepatico de pacientes com colestase neonatal extra-hepatica por meio da reação em cadeia da polimerase
Colesthasis is the reduction or the interruption of the bile flow to the duodenun. The classification in causes intrahepatic and extrahepatic is very important, being the biliary atresia (BA) the major cause ofthe later. BA is the most severe hepatic disorder in newborns and its etiopathogenesis remains unknown. Viral involvement has been proposed, including
Publicado em: 2002
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19. Intrapulmonary shunting in the biliary atresia/polysplenia syndrome: reversal after liver transplantation.
One hundred and seventy three children, including 93 with biliary atresia, received liver grafts at Addenbrooke's Hospital between 1983 and 1993. Of these, only seven developed cyanosis due to intrapulmonary shunting as a complication of their liver disease, and all seven of these had the biliary atresia/polysplenia syndrome. Intrapulmonary shunting was conf
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20. Association of the reovirus S1 gene with serotype 3-induced biliary atresia in mice.
A panel of serotype 3 (T3) reovirus strains was screened to determine their relative capacities to cause lethal infection and hepatobiliary disease following peroral inoculation in newborn mice. A wide range of 50% lethal doses (LD50s) was apparent after peroral inoculation of the different virus strains. Two of the strains, T3 Abney and T3 clone 31, caused
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21. A multivariable risk factor analysis of the portoenterostomy (Kasai) procedure for biliary atresia: twenty-five years of experience from two centers.
OBJECTIVE: The authors investigated risk factors for failure after portoenterostomy for biliary atresia using univariate and multivariable methods. SUMMARY BACKGROUND DATA: Kasai's portoenterostomy has gained worldwide acceptance as the initial surgical therapy for infants with biliary atresia. Although extended survival has been achieved for many patients,
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22. Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-γ in experimental biliary atresia
The etiology and pathogenesis of bile duct obstruction in children with biliary atresia are largely unknown. We have previously reported that, despite phenotypic heterogeneity, genomic signatures of livers from patients display a proinflammatory phenotype. Here, we address the hypothesis that production of IFN-γ is a key pathogenic mechanism of disease usin
American Society for Clinical Investigation.
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23. Glutathione S-transferases in neonatal liver disease.
AIMS: To investigate the distribution of alpha and pi class glutathione S-transferases (GST) in normal fetal, neonatal, and adult liver; and to examine changes in GST expression in neonatal liver disease. METHODS: alpha and pi class GST were immunolocalised in sections of formalin fixed liver tissue obtained from human fetuses (n = 21), neonates (n = 8), you
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24. Orthotopic liver transplantation for congenital biliary atresia. An 11-year, single-center experience.
OBJECTIVE: The authors analyze a single center's 11-year experience with 190 orthotopic liver transplants for congenital biliary atresia. SUMMARY BACKGROUND DATA: Hepatic portoenterostomy generally is the initial treatment for children with congenital biliary atresia. Despite multiple modifications of the hepatic portoenterostomy, two thirds of treated patie