Toxicology Analysis
Mostrando 13-24 de 37 artigos, teses e dissertações.
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13. Análise da expressão da metalotioneína em duas espécies de peixes, Oreochromis niloticus e Prochilodus lineatus
Metallothioneins (MT) are non enzymatic proteins with with metal-binding ability. It has been used as a biomarker for environmental pollution by the analysis of its expression in several fish species. The tilapia is a commonly used model in studies of animal toxicology and some of these species have a well characterized MT sequence. Here, the Oreochromis nil
Publicado em: 2008
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14. RESEARCH POTENTIAL OF THE TOXIC ethanol extract of the seeds of Annona coriacea Mart. (Araticum) IN MICE EXPOSED SUBCHRONIC / INVESTIGAÇÃO DO POTENCIAL TÓXICO DO EXTRATO BRUTO ETANÓLICO DAS SEMENTES DE ANNONA CORIACEA MART. (ARATICUM) EM CAMUNDONGOS SUBCRONICAMENTE EXPOSTOS
The araticum (Annona coriacea Mart.) is a typical fruit of the brazilian cerrado used popularly to overcome inflammatory processes. The family Annonaceae presents as the main constituents acetogenins, a class of substances with great cytotoxic and genotoxic potential, and cited as responsible for a disease similar to parkinson in a Caribbean population that
Publicado em: 2008
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15. Níveis de chumbo em leite e sangue de doadoras de banco de leite em município do Sul do Brasil
Brazilian scientific production on the adverse effects of lead on the general population is still very limited. Lead, a potentially toxic substance, has become a public health problem due to its effects, mainly affecting the central nervous system and the effects on the synthesis of heme. The aim of this study is to evaluate the level of lead exposure of don
Publicado em: 2008
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16. Relation between alcohol consumption and the infractions and crashes traffics. / Relação entre o consumo de bebidas alcoólicas e as infrações e acidentes de trânsito
PEREIRA, R. E. Relation between alcohol consumption and the infractions and crashes traffics. 2008. 83f. Dissertação (Mestrado). Faculdade de Ciências Farmacêuticas de Ribeirão Preto Universidade de São Paulo, Ribeirão Preto, 2008. Lately, alcohol consumption has been considered an important public health problem. Ethanol is a type of drug that affect
Publicado em: 2008
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17. Estudo dos mecanismos de ação da hidroquinona e fenol sobre o recrutamento leucocitário em respostas inflamatórias / Study of mechanisms of action of hydroquinone and phenol on leukocyte recruitment in inflammatory response
Hydroquinone (HQ) is one of the metabolites of benzene responsible for the toxic effects of exposure to solvent, as well as being part of the diet, medicines, tobacco and polluting the environment. Considering the immunotoxicity of this substance, our laboratory has investigated the role of exposure to HQ by prolonged period of time on acute inflammatory res
Publicado em: 2008
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18. Toxicology analysis of antidepressants in whole blood with gas chromatography and nitrogen-phosphorus detection / Análise toxicológica de antidepressivos em sangue total por cromatografia em fase gasosa com detector de nitrogênio e fósforo
A gas chromatographic method was developed to determine antidepressants most prescribed in Brazil and their metabolites (amitriptyline, imipramine, clomipramine, desmethylclomipramine, desipramine, nortriptyline, fluoxetine, norfluoxetine, and sertralina) in whole blood, using solid phase extraction and gas chromatography with nitrogen-phosphorus detection.
Publicado em: 2007
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19. Development and application of toxicological analysis in the diagnosis and prognosis of acute intoxication by paraquat and diquat / Desenvolvimento e aplicação das análises toxicológicas no diagnóstico e prognóstico da intoxicação aguda por paraquat e diquat
Uma das classes químicas de herbicidas que merece particular atenção é a dos bipiridílicos, representada pelo paraquat e diquat. Atualmente, muitos países têm banido ou restringido o uso destes herbicidas devido à grande quantidade de casos de intoxicação acidental, suicídio e envenenamento (tentativa de homicídio) ocorridos no passado. Em contra
Publicado em: 2007
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20. AvaliaÃÃo toxicolÃgica reprodutiva do fitoterÃpico sanativoÂ
The effects of the administration of Sanativo (SAN) were investigated on the pregnancy in Wistar rats. Four groups of female rats (5-8/group) were treated orally with SAN (67, 335 and 1675mg/kg) or water during the pregnancy period (1st to the 21st day) and during each one of the two first phases of pregnancy: pre-implantation (1st to the 6th day) and orga
Publicado em: 2007
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21. A Importância dos centros de informação e assistência toxicologica e sua contribuiçãona sua minimização dos agravos à saúde e ao meio ambiente no Brasil
According to estimates, thousands of products that are potentially hazardous to human health and environmental homeostasis 2 (medicines, cleaning products, pesticides, cosmetics, and other chemical and biological agents) are now on the market, and that dozens more enter the market every year. Based on an analysis of documents and the pertinent legislation, t
Publicado em: 2006
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22. Análise de fármacos em material biológico: acoplamento microextração em fase sólida "no tubo" e cromatografia líquida de alta eficiência
A new solid phase microextraction (SPME) system, known as in-tube SPME, was recently developed using an open tubular fused-silica capilary column, instead of an SPME fiber, as the SPME device. On-line in-tube SPME is usually used in combination with high performance liquid chromatography. Drugs in biological samples are directly extracted and concentrated in
Química Nova. Publicado em: 2005-10
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23. Talinum patens: Análise por ativação neutrônica instrumental e prospecção fitoquímica
The use of plants for many diseases treatment is a millenary knowledge. These are the great importance for the formation of actual medicine bases. Actually, more than 25 % of the all drugs prescribed in the world are obtained from plants. The medicinal plants and other vegetable materials market reach to around two billions dollars. The researches of natural
Publicado em: 2005
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24. Estudo dos casos de intoxicação ocasionadas pelo uso de agrotóxicos no estado do Paraná, durante o período de 1993 a 2000 / Cases of intoxication caused by the use of pesticides in the State of Paraná during the period of 1993 to 2000: a study
The state of Paraná is responsible for more than 20% of the national grain production. Its agricultural structure is organized in small and mediumsized properties where the labor force comes mainly from families. In order to mantain and also increase productivity, the agriculture system in Paraná makes intensive use of the available products in the market,
Publicado em: 2005