Therapeutics
Mostrando 37-48 de 578 artigos, teses e dissertações.
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37. Estrogen and progesterone promote breast cancer cell proliferation by inducing cyclin G1 expression
Breast cancer is the most common cause of cancer among women in most countries (WHO). Ovarian hormone disorder is thought to be associated with breast tumorigenesis. The present study investigated the effects of estrogen and progesterone administration on cell proliferation and underlying mechanisms in breast cancer MCF-7 cells. It was found that a single ad
Braz J Med Biol Res. Publicado em: 01/03/2018
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38. Biofilm production by clinical isolates of Pseudomonas aeruginosa and structural changes in LasR protein of isolates non biofilm-producing
ABSTRACT Introduction: Biofilm production is an important mechanism for the survival of Pseudomonas aeruginosa and its relationship with antimicrobial resistance represents a challenge for patient therapeutics. P. aeruginosa is an opportunistic pathogen frequently associated to nosocomial infections, especially in imunocompromised hosts. Objectives: Analyz
Braz J Infect Dis. Publicado em: 2018-03
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39. Isolation and identification of cytotoxic compounds from a fruticose lichen Roccella montagnei, and it's in silico docking study against CDK-10
ABSTRACT Roccella montagnei Bél. belongs to lichen family Roccelleceae growing luxuriantly along the coastal regions of India. As Roccella has been shown to be bioactive, we prepared methanolic extract and assessed its anticancer potential. The methanolic extract showed significant in vitro cytotoxic activity against four human cancer cell lines such as col
Rev. bras. farmacogn.. Publicado em: 2017-12
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40. Decades of research in drug targeting using gastroretentive drug delivery systems for antihypertensive therapy
ABSTRACT The limitations in absorption of drugs with narrow absorption window, or those unstable in the intestinal pH or those exhibiting low solubility at high pH are primary candidates for gastroretentive drug delivery systems (GRDDS). The delivery system has been widely explored for its commercial potential for a wide variety of therapeutic agents. GRDDS
Braz. J. Pharm. Sci.. Publicado em: 26/10/2017
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41. Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics
Abstract: In the late 90's there was a change in both the route of transmission and the people at risk for sporotrichosis. This zoonotic cat-man alternative transmission route elicited changes in strategies to control the epidemic. There was a progressive increase in the number of cases involving especially children and the elderly. In addition to becoming h
An. Bras. Dermatol.. Publicado em: 2017-10
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42. Endophytic Fungi as Novel Resources of natural Therapeutics
ABSTRACT Fungal endophytes constitute a major part of the unexplored fungal diversity. Endophytic fungi (EF) are an important source for novel, potential and active metabolites. Plant-endophyte interaction and endophyte -endophyte interactions study provide insights into mutualism and metabolite production by fungi. Bioactive compounds produced by endophytes
Braz. arch. biol. technol.. Publicado em: 21/08/2017
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43. Translational Science: How experimental research has contributed to the understanding of spontaneous Physical Activity and Energy Homeostasis
Abstract Spontaneous physical activity (SPA) consists of all daily living activities other than volitional exercise (e.g. sports and fitness-related activities). SPA is an important component of energy expenditure and may protect from overweight and obesity. Little is known about the biological regulation of SPA, but animal researchhas contributedsignificant
Motriz: rev. educ. fis.. Publicado em: 02/05/2017
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44. Premaxilla: an independent bone that can base therapeutics for middle third growth!
RESUMO A descrição inicial da pré-maxila teve a participação de Goethe. Na face, em determinado período do crescimento e desenvolvimento, têm-se a pré-maxila como um osso independente e, depois, semi-independente para, finalmente, se integrar totalmente à maxila. A formação da pré-maxila atua como um elemento estabilizador dentro do esqueleto fac
Dental Press J. Orthod.. Publicado em: 2017-04
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45. Primary myelofibrosis: current therapeutic options
ABSTRACT Primary myelofibrosis is a Philadelphia-negative myeloproliferative neoplasm characterized by clonal myeloid expansion, followed by progressive fibrous connective tissue deposition in the bone marrow, resulting in bone marrow failure. Clonal evolution can also occur, with an increased risk of transformation to acute myeloid leukemia. In addition, di
Rev. Bras. Hematol. Hemoter.. Publicado em: 2016-09
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46. Detection of apoptosis in pemphigus vulgaris by TUNEL technique
Abstract: Background: Pemphigus is part of a group of blistering diseases that affect the skin and mucous membranes. Based on its autoimmune origin, autoantibodies develop in pemphigus that are directed toward cell surface components of keratinocytes. However, some data cannot be explained, such as the lack of a relationship between autoantibody levels and
An. Bras. Dermatol.. Publicado em: 2016-06
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47. Artemisia annua increases resistance to heat and oxidative stresses, but has no effect on lifespan in Caenorhabditis elegans
Abstract It is suggested that oxidative stress induced by cellular reactive oxygen species is one of the major causal factors of aging. The effect of dietary supplementation of anti-oxidants on response to environmental stressors and lifespan has been studied in various model organisms. In the present study, we examine the effect of Artemisia annua extract o
Food Sci. Technol. Publicado em: 31/05/2016
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48. Fonoterapia vocal e fisioterapia respiratória com idosos saudáveis: revisão de literatura
RESUMO Este estudo tem como tema a fonoterapia vocal e a fisioterapia respiratória no idoso saudável. O objetivo do presente estudo foi revisar a literatura sobre fonoterapia vocal e sobre fisioterapia respiratória com idosos saudáveis. Foi realizado um levantamento bibliográfico de artigos publicados entre 2004 e 2014 nas bases de dados Lilacs, Bireme,
Rev. CEFAC. Publicado em: 2016-04