Superoxide Anion Radical
Mostrando 1-12 de 73 artigos, teses e dissertações.
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1. Diethyl Selenodiglycolate: An Eco-Friendly Synthetic Antioxidant with Potential Application to Inflammatory Disorders
This study describes a single step, high yield and purity, ecofriendly and scalable procedure to prepare a selenium derivative (diethyl selenodiglycolate). Diethyl selenodiglycolate rapidly reduces hypochlorous acid (HOCl, second-order rate constant of 7 × 107 M−1 s−1) to generate its corresponding selenoxide. In activated HL-60 cells, diethyl selenodig
J. Braz. Chem. Soc.. Publicado em: 2020-06
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2. Fatty acid composition of vegetable oil blend and in vitro effects of pharmacotherapeutical skin care applications
Vegetable oils have been used for a plethora of health benefits by their incorporation in foods, cosmetics, and pharmaceutical products, especially those intended for skin care. This study aimed to investigate the cutaneous benefits of a vegetable oil blend (VOB) formulation and its fatty acid composition. The anti-inflammatory activity was studied in macrop
Braz J Med Biol Res. Publicado em: 14/02/2019
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3. Isolation and characterization of flavanols from Anthocephalus cadamba and evaluation of their antioxidant, antigenotoxic, cytotoxic and COX-2 inhibitory activities
ABSTRACT In search of lead molecules for use in disease prevention and as food additive from natural sources, two flavanols were isolated from leaves of Anthocephalus cadamba (Roxb.) Miq., Rubiaceae. Their structures were established as 6-hydroxycoumarin-(4"→8)-(-)-epicatechin and 6-hydroxycoumarin-(4"→8)-(-)-epicatechin-(4→6‴)-(-)-epicatechin on the
Rev. bras. farmacogn.. Publicado em: 2016-08
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4. Antioxidant, DNA damage protective, neuroprotective, and α-glucosidase inhibitory activities of a flavonoid glycoside from leaves of Garcinia gracilis
Abstract The leaves of Garcinia gracilis Pierre, Clusiaceae, have been used as flavouring materials in food, with no previous reports of their biological activities and chemical constituents. In this study, the methanolic extract of G. gracilis afforded three compounds namely apigenin-8-C-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (1), 5-hydroxymethyl
Rev. bras. farmacogn.. Publicado em: 2016-06
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5. Antioxidant activities and lutein content of 11 marigold cultivars (Tagetes spp.) grown in Thailand
Antioxidant activities and total phenolic content (TPC) were analyzed in ethanol extracts of 11 marigold cultivars grown in Thailand. Antioxidant activity assays performed in this study were the 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical cation scavenging activity, ferric ion reducing antioxidant power (FRAP), 2,2-diphenyl-1-picry
Food Sci. Technol. Publicado em: 2015-04
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6. Resistance of oxidative stress in biofilm and planktonic cells
This work studied the susceptibility of biofilm produced by E. coli to oxidative stress, and compared the components of free radicals defences: level of glutathione, catalase and dismutase activities in planktonic and biofilm located cells. Results showed the diversity of responses to oxidative stress in bacterial cells in log or stationary phases in both pl
Braz. arch. biol. technol.. Publicado em: 2015-04
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7. Antioxidant activities of kombucha prepared from three different substrates and changes in content of probiotics during storage
Kombucha is a health-promoting fermented beverage worldwide. The present study compared the free-radical scavenging abilities and total reducing power (TRP) of kombucha prepared from low-cost green tea (LGTK), black tea (BTK), and tea powder (TPK). LGTK had the highest scavenging abilities against 2,2-diphenyl-1-picrylhydrazyl (DPPH), superoxide anion and hy
Food Sci. Technol. Publicado em: 25/03/2014
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8. Effect of Bothrops alternatus snake venom on macrophage phagocytosis and superoxide production: participation of protein kinase C
Envenomations caused by different species of Bothrops snakes result in severe local tissue damage, hemorrhage, pain, myonecrosis, and inflammation with a significant leukocyte accumulation at the bite site. However, the activation state of leukocytes is still unclear. According to clinical cases and experimental work, the local effects observed in envenenoma
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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9. Adaptação oxidativa e funcional progressiva do sistema cardiopulmonar secundária à hipertensão arterial pulmonar em ratos
Pulmonary Arterial Hypertension (PAH) is a disease that affects the pulmonary vessels, essentially pre-capillaries, leading to remodeling of the vascular wall. It is characterized hemodynamic syndrome, which is the increase in pulmonary vascular resistance and right ventricular afterload. A growing body of evidence shows the involvement of oxidative stress i
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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10. Atividade peroxidásica da enzima superóxido dismutase 1 humana: produção do radical carbonato, dimerização covalente da enzima e implicações para a esclerose lateral amiotrófica / Peroxidase activity of human superoxide dismutase 1: production of the carbonate radical, covalent dimerization of the enzyme, and implications to amyotrophic lateral sclerosis
A esclerose lateral amiotrófica (ELA) é uma doença neurodegenerativa que afeta os neurônios motores levando a atrofia muscular e morte por insuficiência respiratória. Esta patologia se manifesta de forma esporádica ou familiar, que são indistinguíveis clinicamente. Mutações na enzima antioxidante superóxido dismutase 1 (hSod1) respondem por aprox
Publicado em: 2010
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11. Estudo das propriedades antioxidantes de complexos nitrosilados de rutênio
This study shows the antioxidant and secondary the cytotoxic activity of five different ruthenium nitrosyl complexes: trans-[Ru(NH3)4(L)(NO)]Cl3 (A - D; being (A) L = Caffeine, (B) L = Theophylline, (C) L = Methyl-1-imidazole, (D) L = Benzoimidazole), and (E) cis-[Ru(NH3)4(NO)2]Cl3. Only the complex (A) (L = Caffeine) presented significant reactivity identif
Publicado em: 2009
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12. Capacidade antioxidante de farinhas de resíduos de frutas tropicais. / Antioxidant capacity of tropical flour fruits residues.
Alternativas economicamente vantajosas com exploração completa do conteúdo antioxidante de resíduos de frutas tropicais de fábricas de sucos foram estudadas no estado de Alagoas, Brasil. Assim, extratos metanólicos de farinhas de resíduos de acerola (FRAC), maracujá (FRMA) e abacaxi (FRAB) foram avaliados quanto a sua capacidade antioxidante. Para is
Publicado em: 2008