Schwann Cells
Mostrando 25-36 de 276 artigos, teses e dissertações.
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25. TNF and NGF involvement in the nerve damage of leprosy. / Envolvimento do TNF e do NGF na lesão neural da hanseníase.
O dano nervoso, característico da hanseníase, é causa de deformidade nos pacientes e está diretamente relacionado à invasão das células de Schwann (CS) pelo Mycobacterium leprae (M. leprae). Já foi descrito que o sítio de lesão do nervo é rico em mediadores extracelulares incluindo citocinas, fatores de crescimento e proteases sendo altamente regu
Publicado em: 2008
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26. Anatomia ultraestrutural do nervo frênico de ratos: alterações decorrentes do diabete experimental crônico.
Streptozotocin (STZ) induced diabetes is known to cause a reduction of both conduction velocity and axon caliber in rat nerves and also a decrease in muscle fiber size. In the present study we investigated the phrenic nerve neuropathy, due to experimental diabetes induced by STZ and the evolution of this neuropathy in diabetic rats treated with insulin. Prox
Publicado em: 2008
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27. Mecanismos de patogenia do Mycobacterium leprae: Análise de proteínas extracelulares e efeitos sobre o metabolismo lipídico do hospedeiro. / Mechanisms of Mycobacterium leprae pathogenesis: Analysis of the extracellular proteins and effect on the host lipid metabolism.
The complete sequence of the Mycobacterium leprae genome, together with recent advances in the definition of its proteome, are contributing to our understanding of leprosy pathogenesis, so far a difficult task due to the unique properties of this bacterium. The major goal of the present study was to identify and functionally characterize extracellular M. lep
Publicado em: 2008
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28. Influencia dos polimeros poli caprolactona (PCL) e poli L-acido latico (PLLA), sobre a expressão de componentes da membarna de celulas de Schwann in vitro e in vivo / Influence of poly caprolactone (PCL) and poly L-lactic acid (PLLA) polymers on Schwann cell basal lamina components expression in vitro and in vivo
The present study proposed a new approach to produce tubular conduits designed for peripheral nerve repair. In this sense, membranes of PLLA and PCL were obtained after solvent evaporation and wrapped around a mandrel. The effectiveness of the nerve regeneration was compared with polyethylene and PCL extruded prosthesis 30 and 60 days after surgery. The comp
Publicado em: 2007
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29. Rat bone marrow mesenchymal stem cells differentiation in culture conditioned medium by Schwann cells / Estudo da diferenciação de celulas tronco mesenquimais da medula ossea de ratos em meio de cultura condicionado por celulas de Schwann
As células tronco são células indiferenciadas capazes de se auto replicar e de se diferenciar em diversos tipos celulares maduros com funções especializadas. As células tronco de medula óssea são particularmente interessantes por serem células multipotentes, ou seja, geram células de diversos tecidos, são de fácil obtenção através da aspiraç�
Publicado em: 2007
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30. O MODELO DESMIELINIZANTE DO BROMETO DE ETÍDIO (BE): ESTUDOS MORFOLÓGICOS EM CAMUNDONGOS C57BL/6 NORMAIS E KNOCKOUT PARA CONEXINA 32 / ETHIDIUM BROMIDE (EB) DEMYELINATING MODEL: MORPHOLOGIC STUDIES IN C57BL/6 NORMAL AND CX 32 KNOCKOUT MICE
Light and ultraestructural changes of central and peripheral nervous system lesions in mice KO for connexin-32 and submitted to the ethidium bromide gliotoxic demyelinating model are described. Their KO condition was tested with PCR and a negative connexin-32 labelling was performed by immunofluorescence. The experimental animals were C57BL/6 normal mice and
Publicado em: 2007
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31. An immunohistochemical, clinical and electroneuromyographic correlative study of the neural markers in the neuritic form of leprosy
The nerve biopsies of 11 patients with pure neuritic leprosy were submitted to routine diagnostic procedures and immunoperoxidase staining with antibodies against axonal (neurofilament, nerve growth factor receptor (NGFr), and protein gene product (PGP) 9.5) and Schwann cell (myelin basic protein, S-100 protein, and NGFr) markers. Two pairs of non-adjacent h
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-08
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32. Delayed Schwann cell and oligodendrocyte remyelination after ethidium bromide injection in the brainstem of Wistar rats submitted to streptozotocin diabetogenic treatment
Schwann cell disturbance followed by segmental demyelination in the peripheral nervous system occurs in diabetic patients. Since Schwann cell and oligodendrocyte remyelination in the central nervous system is a well-known event in the ethidium bromide (EB) demyelinating model, the aim of this investigation was to determine the behavior of both cell types aft
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-05
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33. Expression of the receiver for mannose in cells of Schwann and Schwannoma ST88-14. / Expressão do receptor para manose em células de Schwann e Schwannoma ST88-14.
The mannose receptor (MR) is a transmembrane glycoprotein that is expressed in several cell types but little or no information is available on Schwann cells (SC). We show that rodent SC in primary cultures of dissociated cells or explant nerve cultures and a human Schwannoma cell line (ST88-14) bind the exogenous MR ligand neoglycoprotein mannosyl/bovine ser
Publicado em: 2006
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34. Schwann cells for spinal cord repair
The complex nature of spinal cord injury appears to demand a multifactorial repair strategy. One of the components that will likely be included is an implant that will fill the area of lost nervous tissue and provide a growth substrate for injured axons. Here we will discuss the role of Schwann cells (SCs) in cell-based, surgical repair strategies of the inj
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-06
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35. Study of anti- apoptotic effect of the Mycobacterium leprae in human Schwann cells / Estudo do Efeito Anti-Apoptótico do Mycobacterium leprae em Células de Schwann Humanas
A Hanseníase, causada pelo Mycobacterium leprae, apresenta como sintoma clínico mais relevante lesões no sistema nervoso periférico. As estratégias utilizadas pelo M. leprae para infectar e se multiplicar nas células de Schwann (CS) são, contudo, pouco conhecidas. Neste trabalho investigamos o efeito anti-apoptótico do M. leprae sobre a célula hospe
Publicado em: 2005
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36. Morphologic spectrum, immunohistochemical characterization and prognosis of the canine haemangiopericytoma / Classificação morfológica, imunoistoquímica e prognóstica dos hemangiopericitomas caninos
Haemangiopericytomas CHP like Schwanomas are cutaneous neoplasms of mesenchymal origin, frequently appearing in dogs, unlike neurofibromas, which are rare on the species. There are cases reported that CHP originates from pericytes, or cells located around blood vessels. They are observed more in limbs such as tissues, they are well defined, big and firm. Hae
Publicado em: 2005