Schwann Cells
Mostrando 13-24 de 276 artigos, teses e dissertações.
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13. Células mononucleares autólogas de medula óssea na regeneração do nervo tibial em coelhos / Autologous mononuclear cells from bone marrow in the regeneration of tibial nerve in rabbits
The regeneration of peripheral nerves after injury has been target in researches for new technologies that lead to good results, so as to get completely restoration of nerve function. For such, many techniques have been developed using synthetic materials associated to exogenous factors that enhance the regeneration process, as mononuclear cells of bone marr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011
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14. Supraorganized collagen enhances Schwann cell reactivity and organization in vitro
We investigated the reactivity and expression of basal lamina collagen by Schwann cells (SCs) cultivated on a supraorganized bovine-derived collagen substrate. SC cultures were obtained from sciatic nerves of neonatal Sprague-Dawley rats and seeded on 24-well culture plates containing collagen substrate. The homogeneity of the cultures was evaluated with an
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-07
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15. Emprego do colageno com organização supramolecular na regeneração nervosa periferica in vitro e in vivo / Influence of a naturally supraorganized collagen on the peripheral nerve regeneration in vitro and in vivo
The present study investigated in vitro and in vivo the influence of naturally supraorganized collagen on the peripheral nerve regeneration. In the in vitro study, Schwann cells (SCs) were seeded on naturally supraorganized collagen membranes and evaluated with immunocytochemistry and scanning electron microscopy. The results revealed that SCs kept the expre
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/03/2010
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16. Mycobacterium leprae downregulates the expression of PHEX in Schwann cells and osteoblasts
Neuropathy and bone deformities, lifelong sequelae of leprosy that persist after treatment, result in significant impairment to patients and compromise their social rehabilitation. Phosphate-regulating gene with homologies to endopeptidase on the X chromosome (PHEX) is a Zn-metalloendopeptidase, which is abundantly expressed in osteoblasts and many other cel
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-08
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17. Estudo da regeneração simpática pós simpaticotomia seletiva experimental (ramocotomia) / Study of sympathetic regeneration post experimental selective sympathicotomy (ramicotomy)
INTRODUCTION: Thoracic sympathectomy is the only definitive and efficient treatment for primary hyperhidrosis. The ramicotomy is a surgical procedure that is as efficient as conventional sympathectomy but more conservative, having less adverse effects then conventional sympathectomy. This procedure was abandoned on account of the high recurrence rate, attrib
Publicado em: 2009
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18. Diversity among satellite glial cells in dorsal root ganglia of the rat
Peripheral glial cells consist of satellite, enteric glial, and Schwann cells. In dorsal root ganglia, besides pseudo-unipolar neurons, myelinated and nonmyelinated fibers, macrophages, and fibroblasts, satellite cells also constitute the resident components. Information on satellite cells is not abundant; however, they appear to provide mechanical and metab
Brazilian Journal of Medical and Biological Research. Publicado em: 31/10/2008
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19. Morphological and functional characterizations of Schwann cells stimulated with Mycobacterium leprae
Nerve damage, a characteristic of leprosy, is the cause of patient deformities and a consequence of Schwann cells (SC) infection by Mycobacterium leprae. Although function/dysfunction of SC in human diseases like leprosy is difficult to study, many in vitro models, including SC lines derived from rat and/or human Schwannomas, have been employed. ST88-14 is o
Memórias do Instituto Oswaldo Cruz. Publicado em: 2008-06
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20. Inoculação de células de Schwann cultivadas pré-tratadas ou não com as citocinas inflamatórias TGF-beta1 e TN- alfa; na medula espinal contusa de ratos. Análise neuroquímica da plasticidade medular / Inoculation of cultivated cells of Schwann daily pay-treated or not with the inflammatory cytokines TGF-beta1 and TNFalfa in the Spinal cord injuries of rats. Neurochemical analysis of the spinal cord plasticity
The experimental use of Schwann cells is indicated on spinal cord treatment due to the ability of these cells to produce neurotrophic factors and inflammatory cytokines, influencing nervous system environment. Male rats were submitted to a moderate spinal cord contusion (25mm) at 11th thoracic level. Culture Schwann cells were obtained from sciatic nerves an
Publicado em: 2008
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21. Efeitos das células de schwann cultivadas e tratadas com o pedf no trofismo de neurônios medulares cultivados e na recuperação motora de ratos submetidos ao trauma contuso da medula espinal pelo impactor / Effect of the cells of Schwann cultivated and treated with the PEDF in the trophism to spinal cord neurons cultivated and in the motor recovery of rats submitted to the trauma contused of the spinal cords for the Impactor
The present study aimed the assessment of the trophic and regenerative potential of the Schwann cells (SC) and of the neurotrophic factor PEDF on the spinal cord neurons by means of cultures of those cells in vitro as well as in an experimental model of a contused spinal cord lesion in vivo. SC were cultivated from sciatic nerves fragments of young adult rat
Publicado em: 2008
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22. MMP-2 e MMP-9 na patogênese da lesão neural da hanseníase. / MMP-2 and MMP-9 in the patogenesis of neural injury in leprosy.
Matrix metalloproteinases (MMPs) form a family of zinc-dependent endopeptidases that collectively can degrade all components of the extracellular matrix, influencing process such as migration and cellcell interaction. These enzymes play a crucial role in pathological conditions and tecidual injury including diseases of peripheral nervous system and infectiou
Publicado em: 2008
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23. Estudo do efeito de sobrevivência promovido pelo Mycobacterium leprae sobre as células de Schwann: análise do envolvimento dos fatores semelhantes à insulina (IGFs) e da via PI 3-K/Akt. / Study of the effect of survival promoted for the Mycobacterium leprae on the Schwann cell: analysis of the envolvement of the similar factors to the insulin (IGFs) and of way PI 3-K/Akt.
A hanseníase é uma doença crônica causada pelo bacilo Mycobacterium leprae, um patógeno intracelular obrigatório, cujo principal alvo são as células de Schwann (CS), tendo como consequências mais significativas a perda funcional dos nervos periféricos e deformidades. É sabido que patógenos intracelulares bloqueiam vias de apoptose na célula hosp
Publicado em: 2008
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24. Estudo da ação das neuregulinas 1-alfa e 1-beta na regeneração nervosa. Estudo experimental em camundongos isogênicos (C57BL/6J) / Neuregulins 1-alpha e 1-beta on the regeneration the sciatic nerves of (C57BL/6J) isogenic mice using the tubulization technique
PURPOSE: To evaluate the effect of neuregulins 1-alpha and 1-beta on the regeneration the sciatic nerves of male adult C57BL/6J mice, using the tubulization technique. METHODS: Eighteen animals were used, divided into three groups. A polyethylene prosthesis was implanted in a 4.0 mm defect of the left sciatic nerve, as follows: group 1 containing only purifi
Publicado em: 2008