Rna Secondary Structure
Mostrando 13-24 de 1566 artigos, teses e dissertações.
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13. Analise funcional e estrutural da proteina HBx do virus da Hepatite B / Functional and structural analysis of the hepatitis B virus X protein
Chronic infection of the hepatitis B virus (HBV) is one of the causes leading to liver cancer. The HBV genome encodes the 17 kDa onco-protein HBx, a multi-functional protein that contains 10 cysteine residues and is related to induce liver cancer in transgenic mice. The exact function of HBx is still unknown. However, it has been shown that HBx is a potent t
Publicado em: 2005
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14. Estudos moleculares da Selenocisteína Sintase (SELA) de Escherichia coli.
The study of translation processes attracts the interest of a wide range of research groups due to its main role in general cellular metabolism. In particular, the investigation of new amino acid residues, such as selenocysteine and pyrrolysin, which result in an expansion of the genetic code from the traditional 20 residues to a total of 22 residues up to t
Publicado em: 2005
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15. BLOOM BLAST Object Oriented Management: uma solução integrada para gerenciamento dos resultados do BLAST por meio de um paradigma orientado a objetos
Considered a special subject since the beginning of the 80s, bioinformatics can be defined as a way that covers all aspects of acquisition, processing, storage, distribution, analysis and interpretation of biological information. All this happens in a narrow sinergy with the molecular biology fundamental paradigm, which postulates that the genetic informatio
Publicado em: 2003
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16. Vienna RNA secondary structure server
The Vienna RNA secondary structure server provides a web interface to the most frequently used functions of the Vienna RNA software package for the analysis of RNA secondary structures. It currently offers prediction of secondary structure from a single sequence, prediction of the consensus secondary structure for a set of aligned sequences and the design of
Oxford University Press.
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17. siRNA target site secondary structure predictions using local stable substructures
The crystal structure based model of the catalytic center of Ago2 revealed that the siRNA and the mRNA must be able to form an A-helix for correct positing of the scissile phosphate bond for cleavage in RNAi. This suggests that base pairing of the target mRNA with itself, i.e. secondary structure, must be removed before cleavage. Early on in the siRNA design
Oxford University Press.
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18. RNAsoft: a suite of RNA secondary structure prediction and design software tools
DNA and RNA strands are employed in novel ways in the construction of nanostructures, as molecular tags in libraries of polymers and in therapeutics. New software tools for prediction and design of molecular structure will be needed in these applications. The RNAsoft suite of programs provides tools for predicting the secondary structure of a pair of DNA or
Oxford University Press.
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19. RDfolder: a web server for prediction of RNA secondary structure
Prediction of RNA secondary structure is important in the functional analysis of RNA molecules. The RDfolder web server described in this paper provides two methods for prediction of RNA secondary structure: random stacking of helical regions and helical regions distribution. The random stacking method predicts secondary structure by Monte Carlo simulations.
Oxford University Press.
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20. An algorithm for the display of nucleic acid secondary structure.
A simple algorithm is presented for the graphic display of nucleic acid secondary structure. Examples of secondary structure displays are given for tRNA, 5S RNA and part of the 16S RNA. Due to its speed, this algorithm could easily be used in conjunction with secondary structure programs which calculate various alternate structures.
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21. A secondary-structure model for the self-cleaving region of Neurospora VS RNA.
Neurospora VS RNA performs an RNA-mediated self-cleavage reaction whose products contain 2',3'-cyclic phosphate and 5'-hydroxyl termini. This reaction is similar to those of hammerhead, hairpin, and hepatitis delta virus ribozymes; however, VS RNA is not similar in sequence to these other self-cleaving motifs. Here we propose a model for the secondary struct
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22. Pfold: RNA secondary structure prediction using stochastic context-free grammars
RNA secondary structures are important in many biological processes and efficient structure prediction can give vital directions for experimental investigations. Many available programs for RNA secondary structure prediction only use a single sequence at a time. This may be sufficient in some applications, but often it is possible to obtain related RNA seque
Oxford University Press.
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23. A dynamic programming algorithm for finding alternative RNA secondary structures.
Dynamic programming algorithms that predict RNA secondary structure by minimizing the free energy have had one important limitation. They were able to predict only one optimal structure. Given the uncertainties of the thermodynamic data and the effects of proteins and other environmental factors on structure, the optimal structure predicted by these methods
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24. Saccharomyces cerevisiae U1 small nuclear RNA secondary structure contains both universal and yeast-specific domains.
The five small nuclear RNAs (snRNAs) involved in mammalian pre-mRNA splicing (U1, U2, U4, U5, and U6) are well conserved in length, sequence, and especially secondary structure. These five snRNAs from Saccharomyces cerevisiae show notable size and sequence differences from their metazoan counterparts. This is most striking for the large S. cerevisiae U1 and