Pipeline
Mostrando 13-24 de 302 artigos, teses e dissertações.
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13. An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation
Toxoplasma gondii uses epigenetic mechanisms to regulate both endogenous and host cell gene expression. To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins. Step 1 employs PredictNLS and NucPred to identify genes predicted to target eukaryotic nuclei. Step 2 uses GOLi
Mem. Inst. Oswaldo Cruz. Publicado em: 28/05/2018
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14. Evaluation of internal corrosion in a Brazilian iron ore slurry pipeline based on the characterization of scales and tubercles
Abstract The transport capacity of long-distance slurry pumping systems is directly related to the roughness of the pipe. In this context, corrosion plays an important role, especially when dealing with old pipes. Chemical, mineralogical and microstructural analyses were performed on materials removed from the internal surface of an iron ore slurry pipeline
REM, Int. Eng. J.. Publicado em: 2018-04
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15. Draft genome sequence of Chryseobacterium limigenitum SUR2T (LMG 28734T) isolated from dehydrated sludge
ABSTRACT The type strain SUR2 of the novel species Chryseobacterium limigenitum was isolated from a dehydrated sludge of the municipal sewage treatment plant in Dogoše near Maribor in Slovenia. The draft genome, with 60 contigs, 4,697,725 bp, 34.4% of G+C content, was obtained using the Illumina HiSeq 2500-1 platform. Joint Genome Institute Microbial Genome
Braz. J. Microbiol.. Publicado em: 2018-03
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16. Improved reverse transcription-polymerase chain reaction assay for the detection of flaviviruses with semi-nested primers for discrimination between dengue virus serotypes and Zika virus
BACKGROUND The genus Flavivirus includes a variety of medically important viruses, including dengue virus (DENV) and Zika virus (ZIKV), which are most prevalent in Brazil. Because the clinical profile of patients affected by different DENV serotypes or ZIKV may be similar, the development of new methods that facilitate a rapid and accurate diagnosis is cru
Mem. Inst. Oswaldo Cruz. Publicado em: 26/02/2018
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17. From Medicinal Chemistry to Human Health: Current Approaches to Drug Discovery for Cancer and Neglected Tropical Diseases
ABSTRACT Scientific and technological breakthroughs have compelled the current players in drug discovery to increasingly incorporate knowledge-based approaches. This evolving paradigm, which has its roots attached to the recent advances in medicinal chemistry, molecular and structural biology, has unprecedentedly demanded the development of up-to-date comput
An. Acad. Bras. Ciênc.. Publicado em: 15/02/2018
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18. Cancer, Photodynamic Therapy and Porphyrin-Type Derivatives
ABSTRACT This review has two parts. The first one gives an approach to interdisciplinary studies against cancer carried out by many scientists using porphyrin-type substrates as photosensitizers in PDT. Intensive studies were performed for almost six decades. The successes really started in 1993 with the first formulation patented under the trade name Photof
An. Acad. Bras. Ciênc.. Publicado em: 2018
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19. Evaluation of MC1R high-throughput nucleotide sequencing data generated by the 1000 Genomes Project
Abstract The advent of next-generation sequencing allows simultaneous processing of several genomic regions/individuals, increasing the availability and accuracy of whole-genome data. However, these new approaches may present some errors and bias due to alignment, genotype calling, and imputation methods. Despite these flaws, data obtained by next-generation
Genet. Mol. Biol.. Publicado em: 08/05/2017
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20. Metallurgical Characterization of API X65 Steel Joint Welded by MIG Welding Process with Axial Magnetic Field
In this work, API X-65 pipeline steel non-conventionally heat treated, to enhance its mechanical resistance, was welded using the Metal Inert Gas (MIG) process with and without the application of low intensity axial magnetic fields (6 mT). Microstructural and mechanical characterization of the welds revealed that the use of the magnetic field during welding
Mat. Res.. Publicado em: 23/03/2017
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21. Evaluation of Microstructure and Mechanical Properties of Seamless Steel Pipes API 5L Type Obtained by Different Processes of Heat Treatments
This research presents the influence of manufacturing processes and heat treatments on the resulting microstructures and mechanical properties of an API 5L PSL2 seamless steel pipe. Three different conditions are considered - as rolled, normalized and quenched and tempered - to obtain the grades X42R, X42N and X70Q, respectively. Scanning electron microscopy
Mat. Res.. Publicado em: 06/03/2017
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22. Discerning the Fatigue Crack Growth Behavior of API X65 Steels Under Sequence Loading
Abstract This paper presents the effect of sequence loading on fatigue crack growth of API X65 steel tested in room temperature. Most of pipeline steels are subjected to wide spectrum of loading during the length of service. Influence of load history effect can cause a trickier assessment to the fatigue behaviour. The objective of this study is to determine
Lat. Am. j. solids struct.. Publicado em: 2017-02
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23. Effect of Rolling in the Recrystallization Temperature Region Associated with a Post-Heat Treatment on the Microstructure, Crystal Orientation, and Mechanical Properties of API 5L X70 Pipeline Steel
In order to improve the mechanical properties of API X70 pipeline steel, a rolling schedule in the recrystallization temperature region associated with a post heat treatment was proposed. Optical and scanning electron microscopy, electron backscattered diffraction, hardness, and tensile tests were carried out to show the effects of microstructure and crystal
Mat. Res.. Publicado em: 08/12/2016
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24. THE BRAZILIAN EXPERIENCE WITH ETHANOL FUEL: ASPECTS OF PRODUCTION, USE, QUALITY AND DISTRIBUTION LOGISTICS
Abstract The reduction in the availability of fossil fuel increased the search for alternative fuel sources (for example, ethanol). In the Brazilian market, light duty vehicles can be fueled with gasohol (18 up to 27.5 %v/v of anhydrous ethanol in gasoline) and/or hydrous ethanol. To minimize the risk of water-induced phase separation of gasoline-ethanol ble
Braz. J. Chem. Eng.. Publicado em: 2016-12