Pharmacological Research
Mostrando 25-36 de 160 artigos, teses e dissertações.
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25. Hippocampal insulin signaling and neuroprotection mediated by physical exercise in Alzheimer´s Disease
Abstract Epidemiological studies indicate continuous increases in the prevalence of Alzheimer’s Disease (AD) in the next few decades. The key feature of this disease is hippocampal neurodegeneration. This structure has an important role in learning and memory. Intense research efforts have sought to elucidate neuroprotective mechanisms responsible for hipp
Motriz: rev. educ. fis.. Publicado em: 02/05/2017
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26. Folk medicine, phytochemistry and pharmacological application of Piper marginatum
ABSTRACT Piper marginatum Jacq., Piperaceae, is a widely distributed Neotropical species abundant in the Caribbean, exhibiting a characteristic winged petiole and a heart-shaped leaf, its two vegetative landmarks for rapid identification. The species has been employed by traditional indigenous cultures for its reputed medicinal properties. The plant is most
Rev. bras. farmacogn.. Publicado em: 2016-12
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27. Review on research of the phytochemistry and pharmacological activities of Celosia argentea
ABSTRACT Celosia argentea L., Amaranthaceae, is widely used as traditional medicine with a long history in China. It is a unique source of Semen Celosiae whose contributions include purging the hepatic pathogenic fire, improving eyesight, and treating other eye diseases. Over 79 compounds from this plant were isolated and identified, mainly including saponin
Rev. bras. farmacogn.. Publicado em: 2016-12
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28. Effects of endurance training on reduction of plasma glucose during high intensity constant and incremental speed tests in Wistar rats
The aim of this research was to investigate the effects of endurance training on reduction of plasma glucose during high intensity constant and incremental speed tests in Wistar rats. We hypothesized that plasma glucose might be decreased in the exercised group during heavy (more intense) exercise. Twenty-four 10-week-old male Wistar rats were randomly assig
Braz J Med Biol Res. Publicado em: 24/10/2016
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29. The use of Brazilian vegetable oils in nanoemulsions: an update on preparation and biological applications
ABSTRACT Vegetable oils present important pharmacological properties, which gained ground in the pharmaceutical field. Its encapsulation in nanoemulsions is considered a promising strategy to facilitate the applicability of these natural compounds and to potentiate the actions. These formulations offer several advantages for topical and systemic delivery of
Braz. J. Pharm. Sci.. Publicado em: 2016-09
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30. INTERACTION OF CHALCONES WITH CT-DNA BY SPECTROPHOTOMETRIC ANALYSIS AND THEORETICALSIMULATIONS
Chalcones are open chain molecules precursors of flavonoids and isoflavonoids, found spread in edible plants. Because they are easily accessible trough Claisen Shmidt condensation, a great variety of derivatives are available. They have also shown potential in pharmacological and biological applications. It is known that chalcone derivatives display a role i
Quím. Nova. Publicado em: 2016-09
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31. Eryngium creticum – ethnopharmacology, phytochemistry and pharmacological activity. A review
Abstract Eryngium creticum Lam. (E. cyaneum Sibth. & Sm., E. syriacum Lam.), Saniculoideae, Apiaceae is of great importance in the traditional Greco – Arab medicine. This study was carried out in order to contribute to the ethnopharmacological knowledge of this medicinal species. This review describes the botanical characterization and distribution, as wel
Rev. bras. farmacogn.. Publicado em: 2016-06
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32. Exudates used as medicine by the "caboclos river-dwellers" of the Unini River, AM, Brazil – classification based in their chemical composition
Abstract Although the use of exudates in traditional medicine has been commonly observed during ethnopharmacological surveys, few records have been made concerning the scientific merits of these products. The aim of this study was to document ethnopharmacological data and to classify exudates used as medicine by the "caboclos" river-dwellers from the Unini R
Rev. bras. farmacogn.. Publicado em: 2016-06
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33. Long-term non-pharmacological weight loss interventions for adults with type 2 diabetes mellitus
ABSTRACT: BACKGROUND: Most persons with type 2 diabetes are overweight and obesity worsens the metabolic and physiologic abnormalities associated with diabetes. OBJECTIVE: The objective of this review is to assess the effectiveness of lifestyle and behavioral weight loss and weight control interventions for adults with type 2 diabetes. METHODS: Search m
Sao Paulo Med. J.. Publicado em: 2016-04
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34. Induction of apoptosis by zerumbone isolated from Zingiber zerumbet (L.) Smith in protozoan parasite Leishmania donovani due to oxidative stress
Abstract In the present context of emergence of resistance aligned with the conventional anti-leishmanial drugs and occasional treatment failure compelled us to continue the search for replaceable therapeutic leads against Leishmaniainfection. Various ginger spices of the Zingiberaceae family are widely used as spices, flavouring agents, and medicines in Sou
Braz J Infect Dis. Publicado em: 2016-02
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35. Pharmacological characterization of venoms from three theraphosid spiders: Poecilotheria regalis, Ceratogyrus darlingi and Brachypelma epicureanum
Abstract Background Tarantulas (Theraphosidae) represent an important source of novel biologically active compounds that target a variety of ion channels and cell receptors in both insects and mammals. In this study, we evaluate and compare the pharmacological activity of venoms from three taxonomically different theraphos
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 11/08/2015
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36. Ragged Robin (Lychnis flos-cuculi) - a plant with potential medicinal value
Lychnis flos-cuculi L., Caryophyllaceae, contains a number of active compounds belonging to several chemical groups. Previous studies have led to the identification of phytoecdysteroids, triterpenoids saponins, volatile compounds, fatty acid derivatives, phenolic acids and flavonoids. Research on pharmacological activity showed that plant extracts inhibited
Rev. bras. farmacogn.. Publicado em: 2014-12