Pharmacological Research
Mostrando 13-24 de 160 artigos, teses e dissertações.
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13. Synthesis and Biological Evaluation of New Eugenol-Derived 1,2,3- Triazoles as Antimyco bacterial Agents
Eugenol has diverse biological properties including antimycobacterial activity, and the triazole ring is an important heterocycle in antimycobacterial compounds. Therefore, this research aimed to synthesize novel eugenol-derived 1,2,3-triazole as antimycobacterial agents with interesting cytotoxic profile and pharmacological assets. Sixteen compounds were ob
J. Braz. Chem. Soc.. Publicado em: 04/07/2019
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14. Non-pharmacological measures for pain relief in venipuncture in newborns: description of behavioral and physiological responses
RESUMO JUSTIFICATIVA E OBJETIVOS: A punção venosa é considerada um procedimento doloroso, realizado com frequência na unidade de terapia intensiva neonatal. O objetivo deste estudo foi descrever as respostas comportamentais e fisiológicas de recém-nascidos submetidos à punção venosa, com e sem a utilização de medidas não farmacológicas para al�
BrJP. Publicado em: 19/06/2019
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15. Best practices in the delivery process: conceptions from nurse midwives
RESUMO Objetivo: conhecer as concepções de enfermeiras obstétricas sobre o cuidado pautado nas boas práticas às mulheres no processo de parto. Método: pesquisa descritiva com abordagem qualitativa desenvolvida em uma Maternidade-Escola Federal. Realizaram-se entrevistas semiestruturadas com 20 enfermeiras obstétricas, sendo as falas categorizadas co
Rev. Bras. Enferm.. Publicado em: 18/04/2019
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16. Investigation of the effect of the virtual reality application on experimental pain severity in healthy
RESUMO OBJETIVO: El objetivo de este estudio fue investigar el efecto de la aplicación de realidad virtual en el dolor isquémico experimental creado con un instrumento de presión arterial en voluntarios sanos. MÉTODO: La muestra de investigación consistió en 172 estudiantes adultos voluntarios que cumplieron con los criterios de inclusión. A estos i
Rev. Assoc. Med. Bras.. Publicado em: 11/04/2019
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17. Kaempferol suppresses human gastric cancer SNU-216 cell proliferation, promotes cell autophagy, but has no influence on cell apoptosis
Gastric cancer remains a serious threat to human health worldwide. Kaempferol is a plant-derived flavonoid compound with a wide range of pharmacological activities. This study aimed to investigate the effects of kaempferol on gastric cancer SNU-216 cell proliferation, apoptosis, and autophagy, as well as underlying potential mechanisms. Viability, proliferat
Braz J Med Biol Res. Publicado em: 14/02/2019
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18. The Antinociceptive Effect of the Leaves and Flowers Ethanolic Extracts of Tabebuia aurea (Silva Manso) Benth & Hook. F. ex S. Moore
ABSTRACT In view of the traditional use of Tabebuia aurea for treating pain and inflammation, the antinociceptive pharmacological potential of T. aurea ethanolic extracts (TAEE) was investigated through in vivo experimental models. First, the MTT assay was conducted to determine the potential cytotoxicity of the TAEEs. Afterwards, the acetic acid-induced wri
Braz. arch. biol. technol.. Publicado em: 29/11/2018
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19. Therapeutic drug monitoring of benznidazole and nifurtimox: a systematic review and quality assessment of published clinical practice guidelines
Abstract The pharmacological management of adults with chronic-phase Chagas disease is challenging despite it being the recent focus of extensive research. One of the challenges in the current clinical practice guidelines (CPGs) landscape is the existence of non-evidence-based recommendations for the use of laboratory tests in treatment monitoring. This stud
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-12
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20. UPLC/Q-TOF-MS profiling of phenolics from Canarium pimela leaves and its vasorelaxant and antioxidant activities
ABSTRACT Canarium pimela K.D. Koenig, Burseraceae, have a long history of use in the Chinese traditional medicine treatment of various ailments including hypertension, and our research team has reported the anti-hypertensive activity and delineated the mechanism involved in the action. The following research aims to evaluate the vasorelaxant and antioxidant
Rev. bras. farmacogn.. Publicado em: 2017-12
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21. Mirror therapy: A potential intervention for pain management
Summary The consequences of chronic pain and associated disabilities to the patient and to the health care system are well known. Medication is often the first treatment of choice for chronic pain, although side effects and high costs restrict long-term use. Inexpensive, safe and easy to self-administer non-pharmacological therapies, such as mirror therapy,
Rev. Assoc. Med. Bras.. Publicado em: 2017-11
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22. Vouacapane diterpenoids isolated from Pterodon and their biological activities
Abstract The Pterodon genus comprises two native species in Brazil, known as “sucupira-branca” or “faveira”. Their fruits have long been used in Brazilian natural medicine, mainly for the treatment of infections and inflammations. The pharmacological properties of these fruits have often been linked with vouacapane diterpenoids. This review evaluated
Rev. bras. farmacogn.. Publicado em: 2017-10
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23. Pharmacological potential of Maytenus species and isolated constituents, especially tingenone, for treatment of painful inflammatory diseases
ABSTRACT Uses of medicinal plants by people around the world significantly contribute and guide biologically active compounds research that can be useful in the combat against various diseases. Due to a great chemical and structural variety found in their vegetal structures it consolidates ethnopharmacology as an important science for the pharmaceutical sect
Rev. bras. farmacogn.. Publicado em: 2017-08
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24. Guava: phytochemical composition of a potential source of antioxidants for cosmetic and/or dermatological applications
ABSTRACT Guava (Psidium guajava L.) is a native fruit of the American tropics with commercial applications for its taste, flavor and aroma. Numerous pharmacological uses have been described for it, such as the antiseptic effect of its leaves, the use of the fresh fruit and tea from its leaves for the treatment of diarrhea, dysentery, diabetes mellitus, and o
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017