Pbmc
Mostrando 1-12 de 688 artigos, teses e dissertações.
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1. Síntese e caracterização de biovitrocerâmica com adição de SrO a partir de sílica de casca de arroz
Resumo A casca de arroz é um resíduo abundante no Rio Grande do Sul, Brasil, e pode ser utilizada para produção de sílica pura. As biovitrocerâmicas têm a sílica como principal componente. A biocompatibilidade desses materiais pode ser incrementada adicionando componentes, como SrO. Este trabalho objetivou o uso da sílica proveniente da casca de arr
Cerâmica. Publicado em: 2020-12
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2. Pesquisa em doenças inflamatórias intestinais no Brasil: um passo à frente rumo ao cuidado dos pacientes
Maytenus distichophylla is a medicinal species used in Northeast of Brazil. The hexane (HE), chloroform (CE), ethyl acetate (EAE) and methanol (ME) extracts and compounds from its roots were evaluated for their protective activity against Staphylococcus aureus and Candida albicans. The cytotoxicity for chronic myeloid leukemia (K562), acute monocytic leukemi
Arq. Gastroenterol.. Publicado em: 2020-09
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3. CONSTITUENTS FROM ROOTS OF Maytenus distichophylla, ANTIMICROBIAL ACTIVITY AND TOXICITY FOR CELLS AND Caenorhabditis elegans
Maytenus distichophylla is a medicinal species used in Northeast of Brazil. The hexane (HE), chloroform (CE), ethyl acetate (EAE) and methanol (ME) extracts and compounds from its roots were evaluated for their protective activity against Staphylococcus aureus and Candida albicans. The cytotoxicity for chronic myeloid leukemia (K562), acute monocytic leukemi
Quím. Nova. Publicado em: 2020-09
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4. Immunomodulation Properties of Solid-State Fermented Laetiporussulphureus Ethanol Extracts in Chicken Peripheral Blood Monocytes In Vitro
ABSTRACT Laetiporus sp. is recognized as a fungal species traditionally used for medicinal purposes. This study investigated the in-vitro effects of solid-state fermented Laetiporussulphureus ethanol extracts (LSE) for their immunomodulatory potential. Bioactive levels detected in the LSE on different days throughout the fermentation period revealed that the
Braz. J. Poult. Sci.. Publicado em: 20/12/2019
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5. O painel brasileiro de mudanças climáticas na interface entre ciência e políticas públicas: identidades, geopolítica e concepções epistemológicas
Resumo Este artigo examina de modo comparativo dois projetos distintos para o Painel Brasileiro de Mudanças Climáticas (PBMC). O primeiro projeto consistiu na criação, por parte de cientistas brasileiros, de um painel nacional aos moldes do Painel Intergovernamental sobre Mudanças Climáticas (IPCC). Já o segundo foi a tentativa de um formulador de pol
Sociologias. Publicado em: 02/09/2019
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6. Expression of FoxP3 in different forms of leprosy and reactions
RESUMO Embora as células T reguladoras (Treg) sejam importantes na regulação imunológica de vários processos patológicos, o papel delas na imunologia da hanseníase ainda precisa ser mais bem avaliado. O objetivo deste trabalho é quantificar o nuclear transcription factor P3 (FoxP3), principal marcador de células Treg, nas diferentes formas de hansen
J. Bras. Patol. Med. Lab.. Publicado em: 02/09/2019
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7. CD4+CD69+ T cells and CD4+CD25+FoxP3+ Treg cells imbalance in peripheral blood, spleen and peritoneal lavage from pristane-induced systemic lupus erythematosus (SLE) mice
Abstract Background: Adaptive immune cells, including CD4+CD69+ and CD4+CD25+FoxP3+ regulatory T (Treg) cells, are important for maintaining immunological tolerance. In human systemic lupus erythematosus (SLE), CD4+CD25+FoxP3+ Treg cells are reduced, whereas CD69 expression is increased, resulting in a homeostatic immune imbalance that may intensify autorea
Adv. rheumatol.. Publicado em: 05/08/2019
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8. Nrf2, NF-κB and PPARβ/δ mRNA Expression Profile in Patients with Coronary Artery Disease
Resumo Fundamentos: O estresse oxidativo e a inflamação estão presentes na doença arterial coronariana (DAC) e estão ligados à ativação do fator de transcrição nuclear kappa B (NF-κB). Para atenuar essas complicações, fatores de transcrição como o fator nuclear eritroide 2-relacionado ao fator 2 (Nrf2) e o receptor ativado por proliferador de
Arq. Bras. Cardiol.. Publicado em: 18/07/2019
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9. Composite-derived monomers affect cell viability and cytokine expression in human leukocytes stimulated with Porphyromonas gingivalis
Abstract Objectives: Dental composites release unreacted resin monomers into the oral environment, even after polymerization. Periodontal cells are, therefore, exposed to substances that potentially elicit the immune inflammatory response. The underlying molecular mechanisms associated with the interaction between resin monomers and human immune cells found
J. Appl. Oral Sci.. Publicado em: 03/06/2019
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10. Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom
Abstract Background: Snake venom phospholipases A2 (PLA2s) have been reported to induce myotoxic, neurotoxic, hemolytic, edematogenic, cytotoxic and proinflammatory effects. This work aimed at the isolation and functional characterization of a PLA2 isolated from Bothrops jararaca venom, named BJ-PLA2-I. Methods and Results: For its purification, three cons
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 17/12/2018
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11. Inulin Induces IL-10 Secretion and Increased FOXP3 Gene Expression in Human Peripheral Blood Mononuclear Cells
ABSTRACT Inulin is an effective prebiotic and its potential in modulating systemic immunity have been proposed. A subpopulation of T cells, named T regulatory cells (Tregs), expressing the Forkhead boxP3 transcription factor are key mediators of peripheral tolerance and suppress undesirable immune responses. These Tregs can be induced by cytokine transformin
Braz. arch. biol. technol.. Publicado em: 29/10/2018
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12. Expression of miR-155, miR-146a, and miR-326 in T1D patients from Chile: relationship with autoimmunity and inflammatory markers
ABSTRACT Objective The aim of this research was to analyze the expression profile of miR-155, miR-146a, and miR-326 in peripheral blood mononuclear cells (PBMC) of 47 patients with type 1 diabetes mellitus (T1D) and 39 control subjects, as well as the possible association with autoimmune or inflammatory markers. Subjects and methods Expression profile of m
Arch. Endocrinol. Metab.. Publicado em: 2018-02