Oxidative Stress And Hplc
Mostrando 1-12 de 34 artigos, teses e dissertações.
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1. Chemical composition of propolis extract and its effects on epirubicin-induced hepatotoxicity in rats
ABSTRACT Propolis is a natural substance, produced by honeybees from the resin of various plants. The purpose of this study was to determine the chemical composition and evaluate the hepatoprotective effect of ethyl acetate extract of propolis from Tigzirt, against the toxicity induced by epirubicin which is a anticancer agent, and belongs to the family of a
Rev. bras. farmacogn.. Publicado em: 26/08/2019
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2. Phytochemical analysis of Juglans regia oil and kernel exploring their antinociceptive and anti-inflammatory potentials utilizing combined bio-guided GC–FID, GC–MS and HPLC analyses
ABSTRACT Juglans regia L., Juglandaceae, is broadly used due to its immunomodulatory effects, potentials in protecting against many sever-disorders, and high safety-profile. The aim of this work is to make a phytochemical analysis of J. regia oil and kernel exploring their antinociceptive and anti-inflammatory potentials utilizing combined bio-guided gas chr
Rev. bras. farmacogn.. Publicado em: 2018-06
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3. Changes in the phenylalanine ammonia lyase activity, total phenolic compounds, and flavonoids in Prosopis glandulosa treated with cadmium and copper
ABSTRACT The aim of the present work is to evaluate the changes on the phenylalanine ammonia lyase (PAL) activity, phenolic compounds accumulation and photochemical efficiency in leaves of P. glandulosa treated with Cd2+ (0.001 M) and Cu2+ (0.52 M) concentrations for 96 h under hydroponic conditions. The results showed that only leaves treated with copper ha
An. Acad. Bras. Ciênc.. Publicado em: 2018-04
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4. UPLC/Q-TOF-MS profiling of phenolics from Canarium pimela leaves and its vasorelaxant and antioxidant activities
ABSTRACT Canarium pimela K.D. Koenig, Burseraceae, have a long history of use in the Chinese traditional medicine treatment of various ailments including hypertension, and our research team has reported the anti-hypertensive activity and delineated the mechanism involved in the action. The following research aims to evaluate the vasorelaxant and antioxidant
Rev. bras. farmacogn.. Publicado em: 2017-12
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5. Reduction of the DNA damages, Hepatoprotective Effect and Antioxidant Potential of the Coconut Water, ascorbic and Caffeic Acids in Oxidative Stress Mediated by Ethanol
ABSTRACT Hepatic disorders such as steatosis and alcoholic steatohepatitis are common diseases that affect thousands of people around the globe. This study aims to identify the main phenol compounds using a new HPLC-ESI+-MS/MS method, to evaluate some oxidative stress parameters and the hepatoprotective action of green dwarf coconut water, caffeic and ascorb
An. Acad. Bras. Ciênc.. Publicado em: 15/05/2017
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6. Ulcer protective potential of standardized hesperidin, a citrus flavonoid isolated from Citrus sinensis
Free radicals play an important role in stomach ulcer formation. The present investigation validates the anti ulcer activity of hesperidin, isolated from Citrus sinensis (L.) Osbeck, Rutaceae, through the assessment of its antioxidant potential over stomach mucosal tissue by histological examination. Hesperidin was isolated from the dried peel of C. sinensis
Rev. bras. farmacogn.. Publicado em: 2014-06
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7. Lipid peroxidation, detoxification capacity, and genome damage in mice after transplacental exposure to pharmaceutical drugs
Data on genome damage, lipid peroxidation, and levels of glutathione peroxidase (GPX) in newborns after transplacental exposure to xenobiotics are rare and insufficient for risk assessment. The aim of the current study was to analyze, in an animal model, transplacental genotoxicity, lipid peroxidation, and detoxification disturbances caused by the following
Braz J Med Biol Res. Publicado em: 10/12/2013
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8. EFEITO in vitro DE Paullinia cupana NO METABOLISMO OXIDATIVO DE ESPERMATOZÓIDES HUMANOS EXPOSTOS AO CLORETO DE METILMERCÚRIO / EFFECT OF Paullinia cupana in vitro oxidative metabolism HUMAN SPERM EXPOSED TO CHLORIDE METHYLMERCURY
Investigations suggests that methylmercury (MeHg) toxicitiy is related to oxidative stress promotion caused by lipid peroxidation of cell membranes as well as genotoxicity. The methylmercury (MeHg) exposition causes production of adverse effects as deterioration of semen quality, testicular degeneration, and male reproductive failure. Since human sperm is a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/02/2012
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9. INVESTIGAÇÃO DA ATIVIDADE ANTIOXIDANTE IN VITRO E DA COMPOSIÇÃO QUÍMICA DE DIFERENTES EXTRATOS DE PLANTAS MEDICINAIS / INVESTIGATION ABOUT IN VITRO ANTIOXIDANT ACTIVITY AND CHEMICAL COMPOSITION OF DIFFERENT EXTRACTS FROM MEDICINAL
O estresse oxidativo (EO) está envolvido no desenvolvimento de várias doenças relacionadas ao sistema nervoso central, tal como a Doença de Alzheimer (DA). Considerando as limitações da terapia existente para a DA, existe ainda a necessidade de novas alternativas médicas. Na primeira parte deste estudo, foi investigada a capacidade antioxidante e a co
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/03/2011
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10. Caracterização de nanopartículas contendo insulina em modelos de animais induzidos ao diabetes / Characterization of nanoparticles containing insulin in animal models induced diabetes
Diabetes Mellitus is a disease whose cases have increased due to the bad habits of life of society. Several strategies have been developed for the treatment of diabetes, especially the controlled release of drugs. The erroneous use of insulin as basal treatment of diabetes takes a problem, since the high dose of the drug can lead to severe hypoglycemia. The
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/08/2010
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11. Mecanismos de toxicidade do conteúdo de sinalizadores luminosos (light-sticks) -- formação de adutos com DNA e dano oxidativo em células em cultura / Mechanisms of toxicity of the contents of beacons (light-sticks) DNA addcts formation and oxidative damage in cultured cells
Bastões plásticos quimioluminescentes, chamados light sticks, são usados por companhias pesqueiras e descartados nas praias. Moradores locais utilizam seus conteúdos como repelentes, óleo bronzeador e medicamento para dores nas articulações. Nós investigamos a reatividade das soluções de bastões de light sticks coletados em praias brasileiras e a
Publicado em: 2010
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12. Atividade antioxidante e hepatoprotetora de plantas brasileiras, contendo compostos fenólicos.
Plants from Brazilian flora were chosen and studied for their in vitro and in vivo antioxidant and in vivo hepatoprotetive activity, especially in relation to phenolic compounds which have several health benefits. These plants include Phyllanthus niruri, Solanum fastigiatum, Solidago microglossa and Baccharis trimera. The aqueous extracts of leaves showed in
Publicado em: 2010