Organ Shortage
Mostrando 1-12 de 14 artigos, teses e dissertações.
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1. Rational Use of Mechanical Circulatory Support as a Bridge to Pediatric and Congenital Heart Transplantation
Abstract Introduction: Donor shortage and organ allocation is the main problem in pediatric heart transplant. Mechanical circulatory support is known to increase waiting list survival, but it is not routinely used in pediatric programs in Latin America. Methods: All patients listed for heart transplant and supported by a mechanical circulatory support betw
Braz. J. Cardiovasc. Surg.. Publicado em: 2018-06
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2. Perfil, crenças, sentimentos e atitudes de familiares doadores e não-doadores de órgãos / Organ donor families and non-donor families attitudes, feelings, beliefs and profile
Organs transplant shortage is a global problem. In Brazil, only a sixth of potential donors who come to the Intensive Care Units become effective donors. The main obstacle to the organs donation and transplantation process is the refuse of families. OBJETIVES: to determine the donors profile, in order to understand which are the most determinant features rel
Publicado em: 2009
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3. Ensaios em economia da sáude : transplantes de rim
A tese abordou questões relacionadas à economia da saúde, particularmente à visão econômica dos transplantes renais. Foi conduzida uma análise de custo-utilidade para verificar qual tratamento, transplante renal ou hemodiálise, possui menor razão de custo por anos de vida ajustados por qualidade. O resultado obtido corrobora as evidências internaci
Publicado em: 2009
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4. Identification of differentialy express genes during the differentiation of stem cells and characterization of mesenchymal progenitor cells / Identificação de genes diferencialmente expressos durante diferenciação de células-tronco e caracterização de células progenitoras mesenquimais
Diabetes mellitus (DM) defines a number of pathologies caused by the lack or deficient action of the insulin hormone. DM1 is caused by an auto-immune attack to insulin secreting β-pancreatic cells, while DM2 is related to ageing and obesity. Pancreas and islet allo-transplantation constitute therapeutic alternatives, but severe organ shortage and the ab
Publicado em: 2008
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5. Pulmonary transplantation.
OBJECTIVE: More than 2700 lung transplants have been performed since the initial clinical success in 1983. The evolution in the techniques of lung transplantation and patient management and the effects on results are reviewed. SUMMARY BACKGROUND DATA: Improvements in donor management, lung preservation, operative techniques, immunosuppression management, inf
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6. Specific tolerance across a discordant xenogeneic transplantation barrier.
Successful induction of tolerance across disparate (discordant) species barriers could overcome the organ shortage that presently limits clinical transplantation. We demonstrate here that xenogeneic swine thymic transplants can induce tolerance to swine antigens in mice, while positively selecting functional host CD4+ T cells. Immunologically normal C57BL/10
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7. Detection of Infectious Baboon Cytomegalovirus after Baboon-to-Human Liver Xenotransplantation
Xenotransplantation is considered to be a solution for the human donor shortage. However, there is a potential risk of transmitting animal infections from the transplanted organ. The known transmissibility and clinical significance of human cytomegalovirus (HCMV) infection after allotransplantation led us to evaluate whether baboon cytomegalovirus (BCMV) tra
American Society for Microbiology.
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8. Tissue engineering, stem cells, cloning, and parthenogenesis: new paradigms for therapy
Patients suffering from diseased and injured organs may be treated with transplanted organs. However, there is a severe shortage of donor organs which is worsening yearly due to the aging population. Scientists in the field of tissue engineering apply the principles of cell transplantation, materials science, and bioengineering to construct biological substi
BioMed Central.
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9. Expression of a functional human complement inhibitor in a transgenic pig as a model for the prevention of xenogeneic hyperacute organ rejection.
The serious shortage of human organs available for transplantation has engendered a heightened interest in the use of animal organs (xenografts) for transplantation. However, the major barrier to successful discordant xenogeneic organ transplantation is the phenomenon of hyperacute rejection. Hyperacute rejection results from the deposition of high-titer pre
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10. Infectious Disease Issues in Xenotransplantation
Xenotransplantation, the transplantation of living organs, tissues, or cells from one species to another, is viewed as a potential solution to the existing shortage of human organs for transplantation. While whole-organ xenotransplantation is still in the preclinical stage, cellular xenotransplantation and extracorporeal perfusion applications are showing pr
American Society for Microbiology.
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11. Split-liver transplantation. The Paul Brousse policy.
OBJECTIVE: The authors objective is to report their recent experience with split-liver transplantation, focusing on the results and the impact on organ shortage. SUMMARY BACKGROUND DATA: There is an insufficient number of organs for liver transplantation. Split-liver transplantation is a method to increase the number of grafts, but the procedure is slow to g
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12. Clinical experience with a bioartificial liver in the treatment of severe liver failure. A phase I clinical trial.
OBJECTIVE: The purpose of this study was to develop a bioartificial liver (BAL) to treat patients with severe liver failure until they can be either transplanted or recover spontaneously. SUMMARY BACKGROUND DATA: Severe acute liver failure is associated with high mortality. Liver transplantation has emerged as an effective therapy for patients who did not re