Opioid System
Mostrando 13-24 de 97 artigos, teses e dissertações.
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13. Antinociceptive and anti-inflammatory activity of hydroalcoholic extracts and fractions from Erythrina mulungu
Erythrina mulungu Mart. ex Benth., Fabaceae, popularly known as mulungu, is used for the treatment of insomnia and disorders of the central nervous system. This study examined the antinociceptive effects of the hydroalcoholic extracts (HAE), the ethyl acetate and chloroformic fractions from E. mulungu in four experimental models of nociception using laborato
Revista Brasileira de Farmacognosia. Publicado em: 21/11/2011
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14. Phytochemical profile and analgesic evaluation of Vitex cymosa leaf extracts
Vitex cymosa Bertero ex Spreng., Lamiaceae, is found in Central and Amazon regions of Brazil, where it is popularly used as antirheumatic. Extracts from the leaves of V. cymosa were tested in analgesia models such as abdominal contortions induced by acetic acid and formalin to test peripheral analgesia; as well as the tail flick and hot plate models, to test
Revista Brasileira de Farmacognosia. Publicado em: 02/09/2011
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15. p-Cymene reduces orofacial nociceptive response in mice
This study investigated the possible antinociceptive effect of p-cymene in different tests of orofacial nociception. The animals (mice) were pretreated (i.p.) with p-cymene (25, 50, 100 mg/kg), morphine (5 mg/kg), or vehicle (0.2% Tween 80+saline), and were then subsequently administered, subcutaneously into their upper lip: formalin, capsaicin, and glutamat
Revista Brasileira de Farmacognosia. Publicado em: 26/08/2011
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16. Cardioprotection conferred by exercise training is blunted by blockade of the opioid system
OBJECTIVES: To investigate the effect of opioid receptor blockade on the myocardial protection conferred by chronic exercise and to compare exercise training with different strategies of myocardial protection (opioid infusion and brief periods of ischemia-reperfusion) preceding irreversible left anterior descending coronary ligation. INTRODUCTION: The acute
Clinics. Publicado em: 2011
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17. Hyptis fruticosa Salzm. ex Benth. (Lamiaceae): caracterização botânica, química, avaliações ecofisiológicas e atividades farmacológicas. / Hyptis fruticosa Salzm. ex Benth. (Lamiaceae): characterization botany, chemistry, ecophysiological assessments and pharmacological activities.
Hyptis fruticosa Salzm. ex Benth. (Alecrim do campo) is an aromatic plant widely used in folk medicine due to its therapeutic properties. Therefore the aim of this work was to undertake botanical, chemical, ecophysiological, and pharmacological studies. The botanical investigations observed and analyzed information about morphological, physiological, and env
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/09/2010
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18. Estudo da atividade antinociceptiva de um novo fator extraído do veneno de Crotalus durissus collilineatus / Study of the antinociceptive activity of a new factor extracted from the venom of Crotalus durissus collilineatus
A propriedade antinociceptiva dos venenos de algumas subespécies de serpentes, principalmente o da espécie Crotalus durissus, tem sido demonstrada em diversos modelos experimentais. O atual trabalho teve como objetivo o isolamento e a caracterização farmacológica de uma substância com efeito analgésico periférico e central presente no veneno da subes
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/02/2010
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19. Study of antinociceptive and antiinflammatory monoterpene a,b-epoxy-carvone and its effect on glutamatergic neurotransmission. / Estudo da atividade antinociceptiva e anti-inflamatória do monoterpeno a,b-Epoxi-carvona e seu efeito sobre a neurotransmissão glutamatérgica
The a, b-epoxy-carvone (EC) monoterpene is found in many essential oils from plants, but can also be obtained through organic synthesis from the R-(-)-carvone. Previous studies have demonstrated that this compound exerts depressant effect on central nervous system (CNS), and is also known to have anticonvulsant effects, antioxidant and antimicrobial activiti
Publicado em: 2010
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20. Atividade Antinociceptiva, em dores agudas, de um novo fator extraído da secreção cutânea de Rhinella jimi (Amphibia Anura) / Antinociceptive activity in acute pain, a new factor extracted from the skin secretion of Rhinella jimi (Amphibia - Anura)
Pain control has been an important focus of health for a long time. The ideal analgesic should be powerful, promoting maximum pain relief, but must submit a minimum adverse symptoms. The opioid agonists are used in treatment of intense acute pains and chronic pains in terminal patients, although they present important side effects, such as constipation, resp
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/12/2009
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21. Estudo da ação psicofarmacológica de Herissantia crispa (L.) Brizicky (Malvaceae)
Herissantia crispa (L.) Brizicky popularly know as malvaísco is a plant which belongs to the Malvaceae family. There arent many reports about H. crispa, however, steroids, flavonoids and glycosidic flavonoids with pharmacological activity have been isolated from this species. Other species of Malvaceae have been used in traditional medicine and many studies
Publicado em: 2009
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22. Avaliação das atividades analgesica e antiinflamatoria da fração hexanica Agave sisalana / Evaluation of activities analgesic and anti-inflammatory of hexanic fraction of Agave sisalana
Pain is defined as complex and vague sensation that involves several factors such as life style and environment. Many times pain is a result of an inflammatory process. The inflammation an imune system response to different kind of stimulus, microorganisms, tissue injuries, miogenic stimulus or even cirurgic traumas, which release several endogens mediators.
Publicado em: 2009
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23. Efeito antinociceptivo do monoterpeno (S)-(-)-álcool perílico em camudongos
Essential oils are natural products with different applications, especially in the area therapeutic and cosmetic. Many essential oils exhibit a variety of pharmacological properties level of CNS, such as anxiolytic, anticonvulsant and antinociceptive. The influence of functional groups in the structures of these molecules in relation to psychopharmacological
Publicado em: 2009
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24. Evaluation of the antinociceptiva and antiinflammatory activity of the essential oil of Hyptis crenata (Pohl) former Benth / Avaliação da atividade antinociceptiva e antiinflamatória do óleo essencial de Hyptis crenata (Pohl) ex Benth
Hyptis crenata (Pohl) ex Benth. is a herbaceous aromatic and medicinal plant, belongs to Lamiaceae, popularly known as salva-do-marajó, malva-do-marajó and hortelã-bravo. This plant is distributed since the mouth of Amazonas River, Marajó Island, Pantanal, and extending up to the states of Minas Gerais. Its essential oil is characterized by presence of m
Publicado em: 2008