Neutrophil Infiltration
Mostrando 13-24 de 175 artigos, teses e dissertações.
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13. An evaluation of the protective effect of an infusion of chilled glucose solution on thermal injury of the bile ducts caused by radiofrequency ablation of the liver
PURPOSE:To evaluate the protective effects of chilling the bile ducts with cold (5°C) 5% glucose solution (GS) during radiofrequency (RF) administration.METHODS:Twenty male pigs (3 mos. old; 25-30 kg) were subjected to RF delivery with chilling (experimental group, N=10) or without chilling (control group, N=10). Half of the animals in each group were eutha
Acta Cir. Bras.. Publicado em: 2015-01
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14. Oral administration of curcumin (Curcuma longa) can attenuate the neutrophil inflammatory response in zymosan-induced arthritis in rats
PURPOSE:To evaluate the effect of curcumin in the acute phase of zymosan-induced arthritis.METHODS:Twenty-eight male rats were subjected to intra-articular infiltration of zymosan of both knees and, in four the infiltration was made with saline. The animals were divided into five groups second received every six hours by gavage: corn oil by (positive and neg
Acta Cir. Bras.. Publicado em: 2014-11
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15. Effects of ischemic preconditioning and cilostazol on muscle ischemia-reperfusion injury in rats
PURPOSE: To evaluate effects of ischemic preconditioning and Cilostazol on muscle ischemia-reperfusion injury. METHODS: Male Wistar rats were submitted to muscle ischemic and reperfusion injury (4h of the left common iliac artery occlusion followed by 1h of reperfusion). Five experimental groups were constituted: Control group (n=4); Ischemia-Reperfusion (I
Acta Cir. Bras.. Publicado em: 2014
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16. Simvastatin attenuates neutrophil recruitment in one-lung ventilation model in rats
PURPOSE: To investigate the anti-inflammatory effects of simvastatin in rats undergoing one-lung ventilation (OLV) followed by lung re-expansion. METHODS: Male Wistar rats (n=30) were submitted to 1-h OLV followed by 1-h lung re-expansion. Treated group received simvastatin (40 mg/kg for 21 days) previous to OLV protocol. Control group received no treatment
Acta Cir. Bras.. Publicado em: 2013-04
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17. Blockade of CXCR1/2 chemokine receptors protects against brain damage in ischemic stroke in mice
OBJECTIVE: Ischemic stroke may result from transient or permanent reductions of regional cerebral blood flow. Polymorphonuclear neutrophils have been described as the earliest inflammatory cells to arrive in ischemic tissue. CXCR1/2 receptors are involved in the recruitment of these cells. However, the contribution of these chemokine receptors during transie
Clinics. Publicado em: 2013
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18. Efeitos da solução salina hipertônica na resposta inflamatória na sepse / Hypertonic saline solution effects in inflammatory response in sepsis
Sepse é a resposta inflamatória sistêmica do hospedeiro à infecção, que pode ser desencadeada por bactérias, vírus ou fungos. Há aumento da produção de mediadores inflamatórios como citocinas, quimiocinas espécies reativas de oxigênio e do recrutamento de neutrófilos. A administração de solução salina hipertônica 7,5% (SH) acarreta na mod
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/10/2012
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19. Análise das células inflamatórias e da proteína anexina 1 no modelo de artrite experimental e reumatóide humana. / Analysis of the inflammatory cells and annexin 1 protein in the experimental model arthritis and in the human rheumatoid .
Rheumatoid arthritis (RA) is a disease characterized by auto-antibody formation, chronic inflammation and joint oedema resulting in injury of affected cartilage and adjacent bone. In the treatment of this disease glucocorticoids (GC) have been used, wich induce genic expression of anti-inflammatory mediators, such as the annexin 1 protein (Anx-A1), and proin
Publicado em: 2010
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20. Estudo do efeito farmacolÃgico da alfa, beta-amirina, uma mistura de triterpenos isolada de Protium heptaphyllum, na pancreatite aguda experimental / Pharmacological study of the effect of alfa,β-amyrin, a mixture of triterpenes isolated from Protium hepthaphyllum in acute pancreatitis experimental
Triterpenes are natural compounds with anti-inflammatory and cytoprotective effects relatively non-toxic. Acute pancreatitis, an inflammation of the pancreas, may lead to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS), conditions that can lead the patient to death. In this study, a mixture of triterpenes isolate
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/11/2009
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21. Treatment of hemorrhagic shock with hypertonic saline solution modulates the inflammatory response to live bacteria in lungs
Shock and resuscitation render patients more susceptible to acute lung injury due to an exacerbated immune response to subsequent inflammatory stimuli. To study the role of innate immunity in this situation, we investigated acute lung injury in an experimental model of ischemia-reperfusion (I-R) followed by an early challenge with live bacteria. Conscious ra
Brazilian Journal of Medical and Biological Research. Publicado em: 04/09/2009
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22. O papel dos neutrófilos na imunidade inata e no desenvolvimento da resposta imune adquirida ao parasita Leishmania amazonensis
Neutrophils provide the first line of defense against infection and also contribute to the initiation of inflammation. However the role of neutrophils in response to Leishmania is not clear yet. Moreover, most of the studies were performed in Leishmania major model of infection, hence there is no information on the involvement of neutrophils in the immune re
Publicado em: 2009
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23. Studies on the leukocyte component and chemotactic mediators of the inflammatory reaction induced by Bothrops moojeni venom. Participation of mast cells and histamine in leukocyte recruitment. / Estudo do componente leucocitário e de mediadores quimiotáticos da reação inflamatória induzida pelo veneno de Bothrops moojeni. Participação de mastócitos e da histamina no recrutamento leucocitário
In this study the effects of Bothrops moojeni venom (BmV) on the cellular component of inflammatory responses and the mechanisms involved in this effect were investigated. The effects of venom on peritoneal and circulating leukocyte numbers and on the release of inflammatory mediators, such as LTB4, TXA2, PGD2, MIP-1 and KC, were assessed. The role of both m
Publicado em: 2009
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24. Caracterização do papel de TLR2 no desenvolvimento da resposta imune após a infecção com Aggregatibacter actinomycetemcomitans / TLR2 signaling is critical for immune protection against Aggregatibacter actinomycetemcomitans infections
Polymorphonuclear leukocytes (PMNs) are the first line of defense against bacterial infections. PMNs express a numerous pattern-recognition receptors (PRR) that facilitate identification of invading microorganisms. Toll-like receptors (TLRs) represent the main class of PRR involved to a recognize pathogenic microorganism. However, the role played by TLR-2 in
Publicado em: 2007