Myocardial Contractility
Mostrando 1-12 de 170 artigos, teses e dissertações.
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1. Effects of Hyperthyroidism on Contractility and Na+/Ca2+ Exchanger Activity in the Isolated Papillary Muscle of Rats
Abstract Background: Hyperthyroidism (Hy) is an endocrine disorder, in which the thyroid hormones markedly alter the cardiac function. Increased myocardial contractility and cardiac output, improvement in diastolic relaxation, changes in electrical activity, increments in ventricular mass, and arrhythmias have been reported. However, the influences of thyro
International Journal of Cardiovascular Sciences. Publicado em: 2022
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2. Essential oil of the leaves of Eugenia sulcata preserve myocardial contractility and does not present immunotoxicity
The essential oil of the leaves of Eugenia sulcata, in the Myrtaceae family, has a demonstrated antihypertensive effect, but its effects on heart muscle and its toxicity have not yet been elucidated. Little chemical or biological data are available for E. sulcata, whether emphasizing the beneficial effects or the pharmacological security of this species. Thi
Braz. J. Pharm. Sci.. Publicado em: 30/09/2019
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3. Lactate-upregulation of lactate oxidation complex-related genes is blunted in left ventricle of myocardial infarcted rats
Lactate modulates the expression of lactate oxidation complex (LOC)-related genes and cardiac blood flow under physiological conditions, but its modulatory role remains to be elucidated regarding pathological cardiac stress. The present study evaluated the effect of lactate on LOC-related genes expression and hemodynamics of hearts submitted to myocardial in
Braz J Med Biol Res. Publicado em: 04/10/2018
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4. Lidocaine and Pinacidil Added to Blood versus Crystalloid Cardioplegic Solutions: Study in Isolated Hearts
Abstract Objective: The present study aimed the functional recovery evaluation after long term of cardiac arrest induced by Custodiol (crystalloid-based) versus del Nido (blood-based) solutions, both added lidocaine and pinacidil as cardioplegic agents. Experiments were performed in isolated rat heart perfusion models. Methods: Male rat heart perfusions, a
Braz. J. Cardiovasc. Surg.. Publicado em: 2018-06
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5. Chagas disease: morbidity profile in an endemic area of Northeastern Brazil
Abstract: INTRODUCTION : This study evaluated the clinical forms and manifestation severities of Chagas disease among serologically reactive individuals from Western Rio Grande do Norte (Northeastern Brazil). METHODS : This cross-sectional study included 186 adults who were evaluated using electrocardiography, echocardiography, chest radiography, and contr
Rev. Soc. Bras. Med. Trop.. Publicado em: 2015-12
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6. A single resistance exercise session improves myocardial contractility in spontaneously hypertensive rats
Resistance training evokes myocardial adaptation; however, the effects of a single resistance exercise session on cardiac performance are poorly understood or investigated. This study aimed to investigate the effects of a single resistance exercise session on the myocardial contractility of spontaneously hypertensive rats (SHRs). Male 3-month-old SHRs were d
Braz J Med Biol Res. Publicado em: 10/07/2015
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7. Myocardial contractility impairment with racemic bupivacaine, non-racemic bupivacaine and ropivacaine. A comparative study
PURPOSE: To study racemic bupivacaine, non-racemic bupivacaine and ropivacaine on myocardial contractility. METHODS: Isolated Wistar papillary muscles were submitted to 50 and 100 mM racemic bupivacaine (B50 and B100), non-racemic bupivacaine (NR50 and NR100) and ropivacaine (R50 and R100) intoxication. Isometric contraction data were obtained in basal cond
Acta Cir. Bras.. Publicado em: 2015-07
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8. Myocardial remodeling and bioelectric changes in tachycardia-induced heart failure in dogs
In this study, electrical and structural remodeling of ventricles was examined in tachycardia-induced heart failure (HF). We studied two groups of weight-matched adult male mongrel dogs: a sham-operated control group (n=5) and a pacing group (n=5) that underwent ventricular pacing at 230 bpm for 3 weeks. Clinical symptoms of congestive HF were observed in bo
Braz J Med Biol Res. Publicado em: 06/09/2013
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9. Acute exposure to lead increases myocardial contractility independent of hypertension development
We studied the effects of the acute administration of small doses of lead over time on hemodynamic parameters in anesthetized rats to determine if myocardial contractility changes are dependent or not on the development of hypertension. Male Wistar rats received 320 µg/kg lead acetateiv once, and their hemodynamic parameters were measured for 2 h. Cardiac c
Braz J Med Biol Res. Publicado em: 01/02/2013
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10. A eritropoietina protege a função sistólica de corações neonatais submetidos a isquemia e reperfusão regional : trabalho experimental / Erythropoietin protects the systolic function of neonatal hearts against ischemiareperfusion injury
Background: The effect of erythropoietin (EPOT) on neonatal hearts is not well understood. The current hypothesis is that erythropoietin has protective effects against ischemia-reperfusion when administered prior to ischemia induction. Methods: Systolic and diastolic indices, as well as the Akt and extracellular regulated kinase (ERK) signaling pathways, wer
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/04/2012
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11. Tension cost correlates with mechanical and biochemical parameters in different myocardial contractility conditions
OBJECTIVES: Tension cost, the ratio of myosin ATPase activity to tension, reflects the economy of tension development in the myocardium. To evaluate the mechanical advantage represented by the tension cost, we studied papillary muscle contractility and the activity of myosin ATPase in the left ventricles in normal and pathophysiological conditions. METHODS:
Clinics. Publicado em: 2012
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12. Efeito potencializador da Angiotensina(1-7) sobre o aumento da tensão sistólica induzida pelo isoproterenol em corações isolados de ratos
The present study was designed to establish the possible interaction between the Angiotensin-(1-7) [Ang-(1-7)] with isoproterenol, adrenergic agonist, in the production of increased myocardial contractility of isolated hearts of adult rats. Hearts were perfused according to Langendorff preparation. It was used first bolus of isoproterenol, laterally to the a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/02/2011