Micro Cell
Mostrando 1-12 de 2473 artigos, teses e dissertações.
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1. MicroRNA-375 inhibits laryngeal squamous cell carcinoma progression via targeting CST1
Abstract Objective: This study aims to explore the effect and mechanism of miR-375 in Laryngeal Squamous Cell Carcinoma (LSCC) cell progression. Methods: LSCC cells (LSC-1 and TU177) were transfected with miR-375-mimic, miR-375-inhibitor or miR-375-mimic + oe-CST1. The expression of miR-375, CST1, MMP-2, and MMP-9 was measured. The effect of miR-375-mimic,
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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2. MicroRNA-124a Protects the Myocardium Against Ischemia Reperfusion Injury Through Regulation of the Notch Signaling Pathway
Abstract Introduction: This study’s objective is to investigate the effect of downregulation of micro ribonucleic acid (miR)-124a on myocardial injury after ischemia reperfusion (I/R) in rats. Methods: Sprague Dawley (SD) rats (n=20) were divided into four groups - sham, I/R, I/R+miR-124a antagomir (I/R+ant-miR-124a), and I/R+ant-normal control (NC). The
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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3. Erythropoietin-producing clear cell renal cell carcinoma associated with secondary polycythemia
ABSTRACT Background Carica papaya Linn. has high nutraceutical and pharmacological values. The leaves possess antimicrobial, anti-tumor and antioxidant properties. They are used to treat thrombocytopenia during dengue fever and the leaf extract is commercially available as tablets under the name Caripill™ (MicroLabs, Bengaluru). Nevertheless, platelet tra
Hematol., Transfus. Cell Ther.. Publicado em: 2021-06
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4. Anti-Micro RNA-221 a Promising Genetic Therapy of Oral Squamous Cell Carcinoma (SCC-25)
Resumo Micro-RNA-221 (miR-221) é um dos miRNAs oncogênicos que desempenham um papel vital no desenvolvimento e progressão de carcinomas orais. O objetivo deste estudo é apresentar uma nova terapia gênica para o carcinoma epidermóide oral por meio do bloqueio da expressão do miR-221 oncogênico por seu inibidor. O presente trabalho foi realizado na lin
Braz. Dent. J.. Publicado em: 2020-11
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5. Identification of the molecular mechanisms associated with acute type A aortic dissection through bioinformatics methods
Aortic dissection is characterized by the redirection of blood flow, which flows through an intimal tear into the aortic media. The purpose of this study was to find potential acute type A aortic dissection (AAAD)-related genes and molecular mechanisms by bioinformatics. The gene expression profiles of GSE52093 were obtained from Gene Expression Omnibus (GEO
Braz J Med Biol Res. Publicado em: 07/11/2019
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6. Torulaspora globosa: rhizosphere yeast promoting lettuce growth on seedlings and under field conditions
RESUMO Micro-organismos promotores de crescimento vegetal (MPCV) auxiliam as plantas pela produção de fitormônios, disponibilização de nutrientes e manutenção da sanidade vegetal. Dentre os MPCV, as leveduras apresentam grande potencial ainda inexplorado. O objetivo deste trabalho foi avaliar a inoculação da levedura rizosférica Torulaspora globos
Hortic. Bras.. Publicado em: 07/11/2019
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7. Upregulation of miR-129-5p increases the sensitivity to Taxol through inhibiting HMGB1-mediated cell autophagy in breast cancer MCF-7 cells
Although Taxol has improved the survival of cancer patients as a first-line chemotherapeutic agent, an increasing number of patients develop resistance to Taxol after prolonged treatment. The potential mechanisms of cancer cell resistance to Taxol are not completely clear. It has been reported that microRNAs (miRNAs) are involved in regulating the sensitivit
Braz J Med Biol Res. Publicado em: 28/10/2019
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8. A comparison of the sealing abilities between Biodentine and MTA as root-end filling materials and their effects on bone healing in dogs after periradicular surgery
ABSTRACT Objectives: To compare the sealing ability and biocompatibility of Biodentine with mineral trioxide aggregate (MTA) when used as root-end filling materials. Methodology: The Cell Counting Kit-8 (CCK-8) assay was used to compare the cytotoxicity of MTA and Biodentine. Twenty-one extracted teeth with a single canal were immersed in an acidic silver
J. Appl. Oral Sci.. Publicado em: 07/10/2019
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9. Small RNA sequencing reveals microRNAs related to neuropathic pain in rats
The present study aimed to identify microRNAs (miRNAs) that are involved in neuropathic pain and predict their corresponding roles in the pathogenesis and development process of neuropathic pain. The rat model of neuropathic pain caused by spared nerve injury (SNI) was established in Sprague-Dawley male rats, followed by small RNA sequencing of the L3–L6 d
Braz J Med Biol Res. Publicado em: 16/09/2019
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10. Interplay of TGFβ signaling and microRNA in thyroid cell loss of differentiation and cancer progression
ABSTRACT Thyroid cancer has been rapidly increasing in prevalence among humans in last 2 decades and is the most prevalent endocrine malignancy. Overall, thyroid-cancer patients have good rates of long-term survival, but a small percentage present poor outcome. Thyroid cancer aggressiveness is essentially related with thyroid follicular cell loss of differen
Arch. Endocrinol. Metab.. Publicado em: 02/09/2019
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11. MicroRNA-21 over expression in umbilical cord blood hematopoietic stem progenitor cells by leukemia microvesicles
Abstract Microvesicles are able to induce the cell of origin’s phenotype in a target cell. MicroRNA-21, as an oncomir, is up-regulated in almost all cancer types such as leukemia which results in cell proliferation. In this study, we examine the ability of leukemia microvesicles to induce proliferation in hematopoietic stem progenitor cells (HSPCs) via mic
Genet. Mol. Biol.. Publicado em: 15/08/2019
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12. MicroRNA-383-5p inhibits the progression of gastric carcinoma via targeting HDAC9 expression
MicroRNAs (miRNAs), as post-transcriptional regulators, have been reported to be involved in the initiation and progression of various types of cancer, including gastric cancer (GC). The present study aimed to investigate the role of miR-383-5p in gastric carcinogenesis. Cell viability was analyzed using CCK-8 kit. Annexin V-fluorescein isothiocyanate/propid
Braz J Med Biol Res. Publicado em: 29/07/2019