Micro Cell
Mostrando 13-24 de 2473 artigos, teses e dissertações.
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13. SYNTHESIS, CHARACTERIZATION AND in vitro CYTOTOXICITY OF Acacia mearnsii PROANTHOCYANIDIN LOADED PLGA MICROPARTICLES
ABSTRACT One of the highlighted areas in the development of new materials is the generation of micro- and nanoparticles as drug carriers which allow the progress in formulations with the ability to release active agents in a controlled way. The proanthocyanidins (PAC) extracted from the bark of the Black Wattle have stood out for their biological activities.
Braz. J. Chem. Eng.. Publicado em: 15/07/2019
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14. lncRNA CCAT1 promotes bladder cancer cell proliferation, migration and invasion
ABSTRACT Objective: To study the expression patterns of long noncoding RNA (lncRNA) colon cancer-associated transcript 1 (CCAT1) and the changes in cell proliferation, apoptosis, migration and invasion induced by silencing CCAT1 in bladder cancer cells. Materials and Methods: The expression levels of CCAT1 were determined using realtime quantitative polyme
Int. braz j urol.. Publicado em: 27/06/2019
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15. Pancreatic β-cell function is inhibited by miR-3666 in type 2 diabetes mellitus by targeting adiponectin
Type 2 diabetes mellitus (T2D) is a common endocrine and metabolic disorder, and poses threats to human health worldwide. Recently, microRNAs (miRNAs) have been suggested to play important roles in the pathophysiology of T2D. In this study, we explored the role of miR-3666 in T2D. miR-3666 was significantly down-regulated in the serum of T2D patients when co
Braz J Med Biol Res. Publicado em: 27/05/2019
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16. Differential expression of microRNA-411 and 376c is associated with hypertension in pregnancy
Preeclampsia is a major reason of morbidity and mortality in pregnant women and perinatal fetus. Hence, it is of prime importance that diagnostic markers are defined to predict chances of preeclampsia in pregnant women. It has been previously shown that microRNA (miRNA)-376c expression is decreased in the placenta of preeclampsia patients at term. Even thoug
Braz J Med Biol Res. Publicado em: 08/04/2019
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17. Kaempferol suppresses human gastric cancer SNU-216 cell proliferation, promotes cell autophagy, but has no influence on cell apoptosis
Gastric cancer remains a serious threat to human health worldwide. Kaempferol is a plant-derived flavonoid compound with a wide range of pharmacological activities. This study aimed to investigate the effects of kaempferol on gastric cancer SNU-216 cell proliferation, apoptosis, and autophagy, as well as underlying potential mechanisms. Viability, proliferat
Braz J Med Biol Res. Publicado em: 14/02/2019
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18. Bone callus formation is highly disrupted by dietary restriction in growing rats sustaining a femoral fracture
Abstract Purpose: To evaluate the effects of food restriction on fracture healing in growing rats. Methods: Sixty-eight male Wistar rats were assigned to two groups: (1) Control and (2) Dietary restriction. After weaning the dietary restricted animals were fed ad libitum for 42 days with 50% of the standard chow ingested by the control group. Subsequentl
Acta Cir. Bras.. Publicado em: 14/02/2019
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19. Astragalus polysaccharides decrease proliferation, migration, and invasion but increase apoptosis of human osteosarcoma cells by up-regulation of microRNA-133a
Osteosarcoma (OS) has a high incidence, malignity, and frequency of recurrence and metastasis. In this study, we aimed to explore the potential anti-cancer effects of Astragalus polysaccharides (APS) on human OS MG63 cells as well as underlying mechanisms. Viability of MG63 cells was assessed by CCK-8 assay to determine the adequate concentration of APS. The
Braz J Med Biol Res. Publicado em: 14/11/2018
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20. MicroRNA-221 promotes cell proliferation, migration, and differentiation by regulation of ZFPM2 in osteoblasts
Bone fracture is a common medical condition, which may occur due to traumatic injury or disease-related conditions. Evidence suggests that microRNAs (miRNAs) can regulate osteoblast differentiation and function. In this study, we explored the effects and mechanism of miR-221 on the growth and migration of osteoblasts using MC3T3-E1 cells. The expression leve
Braz J Med Biol Res. Publicado em: 18/10/2018
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21. Damping of the Woodwind Instrument Reed Material Arundo donax L
The viscoelastic properties (E', G', tanΦ, δ) of Arundo donax (AD) and a polypropylene-beech fiber composite (PPC) were measured from RT to 580K for various frequencies and strains. E' of AD varies between 5250-6250MPa depending on ageing at RT while E'(RT)=2250MPa of PPC is signifcantly lower. E' of the AD is higher than E' of PPC in the whole investigate
Mat. Res.. Publicado em: 04/06/2018
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22. microRNA-3129 promotes cell proliferation in gastric cancer cell line SGC7901 via positive regulation of pRb
Several microRNAs (miRNAs) have been reported as oncogenes or tumor suppressors in many cancers, including gastric cancer (GC). However, the role and molecular mechanism of miR-3129 in GC is largely unknown. We aimed to explore the function and the underlying molecular mechanism of miR-3129 in GC. Cancer tissues and corresponding adjacent tissues were collec
Braz J Med Biol Res. Publicado em: 21/05/2018
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23. Antiproliferative effect of urolithin A, the ellagic acid-derived colonic metabolite, on hepatocellular carcinoma HepG2.2.15 cells by targeting Lin28a/let-7a axis
An abnormality in the Lin28/let-7a axis is relevant to the progression of hepatitis B virus (HBV)-positive hepatocellular carcinoma (HCC), which could be a novel therapeutic target for this malignant tumor. The present study aimed to investigate the antiproliferative and anti-invasive effects of urolithin A in a stable full-length HBV gene integrated cell li
Braz J Med Biol Res. Publicado em: 07/05/2018
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24. miR-27a protects human mitral valve interstitial cell from TNF-α-induced inflammatory injury via up-regulation of NELL-1
MicroRNAs (miRNAs) have been reported to be associated with heart valve disease, which can be caused by inflammation. This study aimed to investigate the functional impacts of miR-27a on TNF-α-induced inflammatory injury in human mitral valve interstitial cells (hMVICs). hMVICs were subjected to 40 ng/mL TNF-α for 48 h, before which the expressions of miR-
Braz J Med Biol Res. Publicado em: 19/04/2018