Mhc Class Ii
Mostrando 1-12 de 749 artigos, teses e dissertações.
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1. Isolation and characterization of mesenchymal stem/stromal cells from Ctenomys minutus
Abstract Mesenchymal stem/stromal cells (MSCs) are multipotent cells distributed in all tissues and characterized by adherence, morphology, immunophenotype and trilineage differentiation potential. The present study aimed to isolate and characterize adherent MSC-like populations from different tissues of Ctenomys minutus, a threatened wildlife rodent popular
Genet. Mol. Biol.. Publicado em: 29/11/2018
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2. Expression of co-stimulatory molecules CD80 and CD86 is altered in CD14 + HLA-DR + monocytes from patients with Chagas disease following induction by Trypanosoma cruzi recombinant antigens
Abstract INTRODUCTION The relationships between monocytes and lymphocytes through MHC class II molecules and costimulatory, are of utmost importance for the production of an efficient immune response. In this work, we assessed the expression of surface molecules CD80 and CD86 on CD14+HLA-DR+ monocytes from patients with Chagas disease. METHODS: The study
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-10
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3. Análise molecular de polimorfismos nos genes HLA-ClASSE II DRB1* e IL7R? possivelmente associados com a susceptibilidade à esclerose múltipla em uma amostra da população do Rio de Janeiro
Multiple sclerosis (MS) is an inflammatory and degenerative disease of the central nervous system (CNS) that affects mainly young adults. MS seems to be a polygenic and multifactorial disease, and genetic susceptibility has been associated mainly with the major histocompatibility complex (MHC), which in humans is the human leukocyte antigen (HLA). Among non-
Arq. Neuro-Psiquiatr.. Publicado em: 2014-06
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4. MHC Class II haplotypes of Colombian Amerindian tribes
We analyzed 1041 individuals belonging to 17 Amerindian tribes of Colombia, Chimila, Bari and Tunebo (Chibcha linguistic family), Embera, Waunana (Choco linguistic family), Puinave and Nukak (Maku-Puinave linguistic families), Cubeo, Guanano, Tucano, Desano and Piratapuyo (Tukano linguistic family), Guahibo and Guayabero (Guayabero Linguistic Family), Currip
Genet. Mol. Biol.. Publicado em: 09/04/2013
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5. Avaliação de potencial agente vacinal contra o S.pyogenes em camundongos transgênicos, portadores de genes HLA de classe II humanos / Evaluation of potential vaccinal agent against s. pyogenes in human HLA class II transgenics mice
A faringite estreptocócica desencadeada pelo Streptococcus pyogenes pode resultar em uma série de doenças humanas e complicações como a febre reumática (FR) em indivíduos predispostos não tratados. A FR é uma doença autoimune que afeta mais de 20 milhões de crianças em países em desenvolvimento. A proteína M presente na membrana do S. pyogenes
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/08/2011
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6. Estudo dos mecanismos envolvidos na ativação policlonal dos linfócitos B durante a fase aguda da infecção pelo Plasmodium chabaudi AS. / Polyclonal antibody induction mechanisms during the acute phase of Plasmodium chabaudi AS malaria.
Polyclonal B cell activation is a feature of the early spleen B cell response to human and murine malaria, which results in intense production of parasite low-affinity IgM and IgG and autoantibodies. Although this response may contribute for the initial parasite control, it may also hinder the generation of high-affinity IgG that guarantees parasite eliminat
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/05/2011
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7. Imunogenicidade da vacina de DNA quimérica LAMP-1/p55Gag do HIV-1 no período neonatal e efeito da imunização materna na resposta vacinal da prole de camundongos. / Immunogenicity of LAMP-1/p55Gag of HIV-1 DNA chimeric vaccine on neonatal period and effect of maternal immunization immune response of vaccinated offspring.
The immunogenicity of LAMP/gag DNA vaccine of HIV-1, which target the antigen to the class II MHC compartment, was evaluated on BALB/c neonate mice and also the effect of maternal immunization on off spring vaccine response was analyzed. The LAMP/gag neonatal vaccination elicited IgG antibody anti-Gag production and augment the IFN-g producing cells to the M
Publicado em: 2009
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8. HLA-DRB1 alleles in four Amerindian populations from Argentina and Paraguay
The major histocompatibility complex (MHC) is one of the biological systems of major polymorphisms. The study of HLA class II variability has allowed the identification of several alleles that are characteristic to Amerindian populations, and it is an excellent tool to define the relations and biological affinities among them. In this work, we analyzed the a
Genetics and Molecular Biology. Publicado em: 2009
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9. Resposta imune intestinal de camundongos geneticamente deficientes em complexo de histocompatibilidade principal (MHC classe I ou II) infectados por Strongyloides venezuelensis
A infecção por Strongyloides sp. induz resposta imune caracterizada por eosinofilia tecidual, mastocitose, produção de citocinas Th2 e anticorpos, tanto em roedores como em humanos. O objetivo desse estudo foi investigar a resposta imune contra a infecção por Strongyloides venezuelensis em camundongos geneticamente deficientes em complexo de histocompa
Publicado em: 2008
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10. Estudo dos polimorfismos do HLA e microssatélites na infecção pelo HIV-1/AIDS. / Study of HLA and microsatellite markers polymorphisms in the HIV-1 disease.
[INTRODUÇÃO] Fatores genéticos do hospedeiro podem promover resistência à infecção pelo HIV-1 e o retardo no curso da doença. O polimorfismo do HLA é considerado determinante na infecção do HIV-1 e AIDS. Os genes HLA, localizados na região de classe I do MHC, ganham destaque nos estudos de associação como fortes candidatos à patogenia da AIDS.
Publicado em: 2008
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11. Low expression of antigen-presenting and costimulatory molecules by lung cells from tuberculosis patients
Costimulatory and antigen-presenting molecules are essential to the initiation of T cell immunity to mycobacteria. The present study analyzed by immunocytochemistry, using monoclonal antibodies and alkaline phosphatase-anti-alkaline phosphatase method, the frequency of costimulatory (CD86, CD40, CD40L, CD28, and CD152) and antigen-presenting (MHC class II an
Brazilian Journal of Medical and Biological Research. Publicado em: 29/10/2007
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12. Imunolocalização e alterações patológicas induzidas pela infecção por Strongyloides venezuelensis em camundongos geneticamente deficientes em MHC de classe I ou II
In the present study, we investigated the mechanisms involved in the immune response of Major Histocompatibility Complex class I or class II knockout mice (MHC I-/- or MHC II-/-), after S. venezuelensis infection. Wild-type C57BL/6 (WT), MHC II -/- and MHC I -/- mice were individually inoculated with 3.000 larvae (L3) of Strongyloides venezuelensis and sacri
Publicado em: 2007