Lymphocyte Phenotypes
Mostrando 1-12 de 66 artigos, teses e dissertações.
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1. Ex vivo T-lymphocyte chemokine receptor phenotypes in patients with chronic Chagas disease
Abstract INTRODUCTION: Elucidating the molecules involved in the inflammatory process of chronic Chagas disease may allow identification of treatment targets. METHODS: The ex vivo phenotypic expression of chemokine receptors CCR1, CCR3, CCR4, CCR5, CXCR2, CXCR3, CXCR4, and CXCR5 on the CD4+ and CD8+ T-cells of patients with chronic Chagas cardiomyopathy
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-09
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2. Células de doadores normais primadas in vitro respondem ao antígeno ovular solúvel e ao peptídeo sintético MAP4 derivado da triose fosfato isomerase do Schistosoma mansoni. / Cells of normal primed givers in vitro answer to the antigen to ovular soluble and synthetic peptíde MAP4 derived from triose-phosphate isomerase of the Schistosoma mansoni.
It has been well established that Schistosoma mansoni induces an initial CD4+ T-cell response. The early events in the immune response to schistosomiasis have been evaluated in mice but few studies have focused on the early response in humans, especially in regard to parasite antigens that are potential vaccine candidates. To study the early immune response
Publicado em: 2007
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3. Baixos nÃveis de lectina ligante de manose podem estar associados a uma maior predisposiÃÃo à doenÃa pelo vÃrus respiratÃrio sincicial sem interferir na ativaÃÃo de linfÃcitos T
Respiratory syncytial virus (RSV) is a major cause of serious lower respiratory tract disease among infants and young children worldwide, and understanding the immune response to its infection is essential for intervention strategies. The innate-response serum mannose-binding lectin (MBL), which recognizes a broad range of pathogens and subsequently activate
Publicado em: 2007
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4. Poliformismo da haptoglobina, status de ferro e proteinas de fase aguda em pacientes infectados pelo virus da imunodeficiencia humana (HIV)
Haptoglobin (Hp) is a plasma protein with antioxidant and immunomodulatory properties. Three main genotypes/phenotypes (Hp1-1, Hp2-1, Hp2-2) show distinctive efficiencies in their activities and have been related to susceptibility and/or outcome in different diseases, including HIV-infection. We compared the Hp genotype distribution between 387 Brazilian HIV
Publicado em: 2005
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5. Imunoperoxidase nos linfomas não hodgkin diagnosticados na Universidade Estadual de Campinas
The non-Hodgkin lymphomas belong to a group of nosologic entities which present ordinary characteristics in relation to both clinical and histology, being in general divided into high and low levels of malignity. The systematization of the many subtypes of the non-Hodgkin lymphomas has been a great problem. Only in the 70 s, in the light of the immunological
Publicado em: 1995
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6. Genetic analysis of lymphocyte activation by lipopolysaccharide Endotoxin.
A genetic study of in vitro lymphocyte blastogenesis by the B-cell mitogen lipopolysaccharide endotoxin has been performed, using both low-responder C3H/HeJ mice and high-responder CBA/J mice. The crossbreeding of these strains produced F1 progeny that were intermediate in responsiveness. Responder types from the backcross of the F1 to the C3H/HeJ strain seg
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7. Quantitative-Trait Loci on Chromosomes 1, 2, 3, 4, 8, 9, 11, 12, and 18 Control Variation in Levels of T and B Lymphocyte Subpopulations
Lymphocyte subpopulation levels are used for prognosis and monitoring of a variety of human diseases, especially those with an infectious etiology. As a primary step to defining the major gene variation underlying these phenotypes, we conducted the first whole-genome screen for quantitative variation in lymphocyte count, CD4 T cell, CD8 T cell, B cell, and n
The American Society of Human Genetics.
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8. B-cell function in vitro during rubella infection.
B-cell function in vitro was studied in patients with natural rubella virus infection. Lymphocyte responses to mitogens in a blast transformation test were decreased at the onset of the rash. Spontaneous immunoglobulin production by peripheral blood lymphocytes was increased during the acute phase of illness. In regulatory T-cell subpopulations, increased pr
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9. Predominant CD4 T-lymphocyte tropism of human herpesvirus 6-related virus.
Human herpesvirus 6 (HHV-6)-related virus was isolated from CD4+ CD8- and CD3+ CD4+ mature T lymphocytes but could not be isolated from CD4- CD8+, CD4- CD8-, and CD3- T cells in the peripheral blood of exanthem subitum patients. HHV-6-related virus predominantly infected CD4+ CD8+, CD4+ CD8-, and CD3+ CD4+ cells with mature phenotypes and rarely infected CD4
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10. Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP
We have introduced a targeted mutation in SH2D1A/DSHP/SAP, the gene responsible for the human genetic disorder X-linked lymphoproliferative disease (XLP). SLAM-associated protein (SAP)-deficient mice had normal lymphocyte development, but on challenge with infectious agents, recapitulated features of XLP. Infection of SAP− mice with lymphocyte choriomening
The National Academy of Sciences.
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11. Bronchoalveolar lavage fluid findings in patients with chronic hepatitis C virus infection.
BACKGROUND: Hepatitis C virus (HCV) infection has recently been incriminated as an aetiological agent in idiopathic pulmonary fibrosis. This study was performed to determine the cellularity and lymphocyte phenotypes of bronchoalveolar lavage (BAL) fluid in patients with chronic hepatitis C. METHODS: BAL fluid and lavage lymphocyte subsets from 13 patients (1
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12. T-lymphocyte subpopulations in relation to immunosuppression in measles and varicella.
Patients with measles or varicella were studied during the acute phase (first week) of illness and, after recovery, by lymphocyte stimulation tests and determination of T-lymphocyte subpopulations, using the monoclonal antibodies Leu 2a and Leu 3a directed at the suppressor/cytotoxic and the helper T-cell subsets, respectively. Low proliferative responses to