Immunocytochemistry
Mostrando 25-36 de 667 artigos, teses e dissertações.
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25. In vitro inhibitory effects of imatinib mesylate on stromal cells and hematopoietic progenitors from bone marrow
Imatinib mesylate (IM) is used to treat chronic myeloid leukemia (CML) because it selectively inhibits tyrosine kinase, which is a hallmark of CML oncogenesis. Recent studies have shown that IM inhibits the growth of several non-malignant hematopoietic and fibroblast cells from bone marrow (BM). The aim of the present study was to evaluate the effects of IM
Braz J Med Biol Res. Publicado em: 25/09/2012
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26. Protection against neurotoxicity by an autophagic mechanism
The objective of the present study was to investigate the effects of 3-n-butylphthalide (NBP) on a 1-methyl-4-phenylpyridinium (MPP+)-induced cellular model of Parkinson’s disease (PD) and to illustrate the potential mechanism of autophagy in this process. For this purpose, rat PC12 pheochromocytoma cells were treated with MPP+ (1 mM) for 24 h following pr
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-05
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27. Marcadores tumorais bioquímicos e imunocitoquímicos em efusões neoplásicas caninas / Biochemical and immunocytochemical tumor markers in canine neoplastic effusions
The cavity effusions frequently occur in the clinical routine of dogs. In most cases the effusions are benign caused by circulatory system disorders. Neoplasms are common causes of effusions in dogs, however not always the tumor cells are found in cytopathologycal analysis. The dosage of tumor markers is an alternative to make the neoplastic effusion diagnos
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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28. Estudo da osteoclastogênese e da remodelação óssea durante a formação e erupção de molares de ratos tratados com bisfosfonatos. / Study of the osteoclastogenesis and bone remodeling during the formation and eruption of molars of bisphosphonate-treated rats.
A erupção dentária depende de uma coordenada interação entre o germe dentário e o tecido ósseo da cripta que o envolve. Para que seja formada a via eruptiva, a reabsorção da porção oclusal da cripta óssea por osteoclastos é indispensável. Os bisfosfonatos são drogas com reconhecida capacidade de inibir a atividade clástica e foram empregados
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/12/2011
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29. Análise da expressão da metaloproteinase de matriz do tipo 9 em esfregaços cérvico-vaginais: um estudo citopatológico / Evaluation of the expression of matrix metalloproteinase type 9 in cervicovaginal smears: a cytological study
The Human Papillomavirus (HPV) are epitheliotropic viruses from family Papillomaviridae, which cause skin or mucous lesions. Carcinoma of the cervix is a major cause of death in women worldwide, and HPV infection a major risk factor for development of cervical carcinoma. During the malignant process, cell migration is a fundamental characteristic of tumor in
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/07/2011
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30. Influência da diminuição da temperatura sobre o fuso meiótico de oócitos de camundongas e de mulheres maturados in vitro / Low temperature influence on meiotic oocyte spindle of mice and humans after maturation in vitro
Introduction: The meiotic spindle of most mammals is sensitive to cooling and depolymerizes even after a slight reduction in temperature. This is well described and studied on matured oocytes at metaphase II (MII). However, little is known about the influence of low temperatures under meiotic spindle of imature oocytes. In this way, we sougth to evaluate: 1)
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/06/2011
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31. Tratamento com taurina e interferon beta influencia a expressão do complexo de histocompatibilidade principal de classe I (MHC I) e a formação de sinapses em células PC12 / Interferon beta and taurine treatment induce major histocompatibility complex class I (MHC I) upregulation and synapse plasticity in PC12 cells
It has been demonstrated that MHC I up regulation by exogenous treatment with interferon beta (IFN beta) influences the glial reaction and the synaptic elimination process. Also, the amino acid taurine has been shown to positively influence neuronal survival and plasticity. Nevertheless, the establishment of an in vitro model for studying the synaptic format
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/02/2011
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32. Análise de uma heme oxigenase funcional em Trypanosoma cruzi / Heme oxygenase analysis in Trypanosoma cruzi
Trypanosoma cruzi, the ethiologic agent of Chagas disease, is transmitted through triatomine vectors during their blood-meal on vertebrate host. These hematophagous insects ingest blood about 6 to 12 times its original weight, reaching in a single meal about 10 mM heme bound to hemoglobin. Heme (iron protoporphyrin IX) is an important molecule in metabolism
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/02/2011
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33. Supraorganized collagen enhances Schwann cell reactivity and organization in vitro
We investigated the reactivity and expression of basal lamina collagen by Schwann cells (SCs) cultivated on a supraorganized bovine-derived collagen substrate. SC cultures were obtained from sciatic nerves of neonatal Sprague-Dawley rats and seeded on 24-well culture plates containing collagen substrate. The homogeneity of the cultures was evaluated with an
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-07
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34. Comparative analysis of the 14-3-3 gene and its expression in Echinococcus granulosus and Echinococcus multilocularis metacestodes
It was suggested that the unlimited proliferative capacity of the Echinococcus multilocularis metacestode may be related to overproduction of the 14-3-3 protein. As is known, the proliferative capacities of E. granulosus and E. multilocularis metacestodes are very different. By comparing the expression levels of the 14-3-3 gene between in vitro-obtained E. g
Publicado em: 2011
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35. Emprego do colageno com organização supramolecular na regeneração nervosa periferica in vitro e in vivo / Influence of a naturally supraorganized collagen on the peripheral nerve regeneration in vitro and in vivo
The present study investigated in vitro and in vivo the influence of naturally supraorganized collagen on the peripheral nerve regeneration. In the in vitro study, Schwann cells (SCs) were seeded on naturally supraorganized collagen membranes and evaluated with immunocytochemistry and scanning electron microscopy. The results revealed that SCs kept the expre
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/03/2010
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36. Kinetoplastid membrane protein-11 is present in promastigotes and amastigotes of Leishmania amazonensis and its surface expression increases during metacyclogenesis
Kinetoplastid membrane protein-11 (KMP-11), a protein present in all kinetoplastid protozoa, is considered a potential candidate for a leishmaniasis vaccine. A suitable leishmaniasis vaccine candidate molecule must be expressed in amastigotes, the infective stage for mammals. However, the expression of KMP-11 in Leishmania amastigotes has been a subject of c
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-05