Glycosaminoglycan
Mostrando 13-24 de 281 artigos, teses e dissertações.
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13. Excreção urinária de glicosaminoglicanos em crianças com bexiga neurogênica secundária a mielomeningocele / Urinary glycosaminoglycan excretion in children with neurogenic bladder secondary to myelomeningocele
A excreção urinária de glicosaminoglicanos (GAG) está alterada em várias patologias do trato urinário; o padrão de excreção pode estar associado com o estado da doença. A excreção urinária de GAG em crianças com bexiga neurogênica (BN) secundária a mielomeningocele (MMC) pode também estar alterada, mas até a presente data não há detalhame
Publicado em: 2011
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14. Análise clínica e estrutural de processos de osteocondrite dissecante da articulação tíbio-társica de equinos / Clinical and structural analysis of osteochondritis dissecans in the tibiotarsal joints of horses
A osteocondrite dissecante (OCD) é uma doença que surge nos equinos durante a fase de desenvolvimento sendo caracterizada pela presença de fragmento osteocondral intra-articular. Pouco se sabe sobre a condição da articulação doente em animais mais velhos, principalmente nos casos assintomáticos, que são operados muitas vezes com a finalidade de come
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/04/2010
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15. Mucopolysaccharidosis I, II, and VI: brief review and guidelines for treatment
Mucopolysaccharidoses (MPS) are rare genetic diseases caused by the deficiency of one of the lysosomal enzymes involved in the glycosaminoglycan (GAG) breakdown pathway. This metabolic block leads to the accumulation of GAG in various organs and tissues of the affected patients, resulting in a multisystemic clinical picture, sometimes including cognitive imp
Genetics and Molecular Biology. Publicado em: 12/11/2010
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16. Noncrystalline uric acid inhibits proteoglycan and glycosaminoglycan synthesis in distal tubular epithelial cells (MDCK)
Hyperuricemia is associated with renal stones, not only consisting of uric acid (UrAc) but also of calcium oxalate (CaOx). Glycosaminoglycans (GAGs) are well-known inhibitors of growth and aggregation of CaOx crystals. We analyzed the effect of noncrystalline UrAc on GAG synthesis in tubular distal cells. MDCK (Madin-Darby canine kidney) cells were exposed t
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-10
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17. A useful routine for biochemical detection and diagnosis of mucopolysaccharidoses
Mucopolysaccharidoses (MPS) constitute, owing to their biochemical, genetical and clinical characteristics, a large and heterogeneous subgroup among the lysosomal storage diseases (LSD). They are caused by deficiency of specific enzymes, which are responsible for glycosaminoglycan (GAG) breakdown during different steps of its degradation pathway. MPS are res
Publicado em: 2010
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18. Glycosaminoglycan distribution in the rat uterine cervix during the estrous cycle
OBJECTIVE: To analyze the amount of glycosaminoglycans in the uterine cervix during each phase of the rat estrous cycle. DESIGN: Based on vaginal smears, forty female, regularly cycling rats were divided into four groups (n = 10 for each group): GI - proestrous, GII - estrous, GIII - metaestrous and GIV - diestrous. Animals were sacrificed at each phase of t
Clinics. Publicado em: 2010
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19. Proteoglicanos de estroma mamário e fibroadenoma humanos em diferentes condições hormonais. / Proteoglycans of human mammary stroma and fibroadenoma under different hormonal conditions.
Proteoglycans are important component of the extracellular matrix, which are involved in its organization and function, as well as in many biological processes. The aim of the present study was to investigate the changes that occur in proteoglycans of human fibroadenoma in comparison to proteoglycans of human normal breast tissue during the menstrual cycle.
Publicado em: 2009
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20. Polymeric microcapsules poduction from sodium alginic acid for cell therapy
Development of polymeric materials has been increasingly emphasized in Biomedicine. Here, we evaluate the use of microcapsules made of Biodritin®, a biocompatible polymer compound which contains sodium alginic acid, a natural polymer extracted from algae, and Cis-Chondroitin sulfate, a glycosaminoglycan from the extracellular matrix. Gelation of this polyme
Materials Research. Publicado em: 2007-12
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21. Characterization of musculoskeletal system in individuals with mucopolysaccharidosis type II : some kinectics features and functional consequences / Caracterização do sistema musculo-esqueletico em individuos com mucopolissacaridose Tipo II : alguns aspectos cineticos e consequencias funcionais
Mucopolysaccharidosis type II (MPS-II) is a rare lysosomal storage disorder caused by deficiency in the activity of the enzyme iduronate-2-sulphatase. This enzyme is responsible for the catabolism of two different glycosaminoglycans (GAGs), dermatan sulfate and heparan sulfate. Lysosomal accumulation of these glycosaminoglycan molecules results in cell, tiss
Publicado em: 2007
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22. Efeito de frações obtidas da fucoidana de Fucus vesiculosus em modelo experimental de artrite induzida por Zymosan
The fucoidan from Fucus vesiculosus is known for having diverse biological properties. This study analyzed the therapeutic action of populations of commercial fucoidan (F. vesiculosus) on zymosan-induced arthritis. Three populations of fucoidan were obtained after acetone fractionation; these were denominated F1 (52.3%), F2 (36.7%) and F3 (10.7%). Chemical a
Publicado em: 2007
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23. Efeito do Fucoidam de Fucus vesiculosus em um modelo experimental de artrite reumatóide
Rheumatoid arthritis (RA) is systemic auto imune disorder. It is caracterized by chronic inflammation of joints leading to progressive erosion of cartilage and bone. We investigated the effect of the administration of fucoidan, sulfated polysaccharides, from algae Fucus vesiculosus in the acute (6h) in zymosan-induced arthritis (AZy). Wistar rats (180-230 g)
Publicado em: 2005
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24. Decorin is one of the proteoglycans expressed in Walker 256 rat mammary carcinoma
Proteoglycan and glycosaminoglycan content was analyzed in a model of rat mammary carcinoma to study the roles of these compounds in tumorigenesis. Hyaluronic acid and proteoglycans bearing chondroitin and/or dermatan sulfate chains were detected in solid tumors obtained after subcutaneous inoculation of Walker 256 rat carcinoma cells. About 10% of sulfated
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-08