Gene Il 15
Mostrando 1-12 de 125 artigos, teses e dissertações.
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1. Suppresses of Astragalus Polysaccharide on E. coli-Induced Injured Intestinal Microvascular through TLR4-NF-κB Signal Pathways in Chickens
ABSTRACT To investigate the hypothesis that APS can attenuate E. coli-induced microvascular dysfunction in chicken intestine, 60 0-day old male chickens were divided into three groups with 5 replications of 4 chicks. Chicken in the APS group were treated with 15 mg APS daily while the others were given 0 mg APS for 6 days. Then all 7-day old chicken were inj
Braz. J. Poult. Sci.. Publicado em: 11/11/2019
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2. Clinical attachment loss and molecular profile of inflamed sites before treatment
Abstract Objective: To monitor early periodontal disease progression and to investigate clinical and molecular profile of inflamed sites by means of crevicular fluid and gingival biopsy analysis. Methodology: Eighty-one samples of twenty-seven periodontitis subjects and periodontally healthy individuals were collected for the study. Measurements of clinica
J. Appl. Oral Sci.. Publicado em: 09/09/2019
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3. Single nucleotide polymorphisms of cytokine-related genes and association with clinical outcome in a Chagas disease case-control study from Brazil
BACKGROUND The severity of chronic chagasic cardiomyopathy (CCC), the most frequent clinical outcome of Chagas disease (CD), has been associated with cytokine-enriched heart tissue inflammation, and high serum levels of transforming growth factor (TGFβ), interferon-gamma (IFNγ), and tumour necrosis factor (TNF). Conversely, increased interleukin (IL)-10 s
Mem. Inst. Oswaldo Cruz. Publicado em: 14/05/2018
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4. A doença de Alzheimer e os polimorfismos no gene da citocina IL-10: há alguma associação?
RESUMO A doença de Alzheimer (DA) é a forma mais comum de demência. Nos últimos 15 anos, uma nova teoria propõe um mecanismo autoimmune como o gatilho para a DA. Associações entre DA e biomarcadores inflamatórios têm sido registradas, contudo com resultados controversos. A interleucina-10 (IL-10), um mediador anti-inflamatório, tem sido apontada co
Arq. Neuro-Psiquiatr.. Publicado em: 2017-09
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5. Campylobacter Jejuni Increases Transcribed Il-1 B and Causes Morphometric Changes in the Ileal Enterocytes of Chickens
Abstract Campylobacteriosis is a worldwide foodborne zoonosis disease caused by Campylobacter jejuni. This microorganism is considered a commensal bacterium in chicken hosts. C. jejuni produces epithelial cell modifications and induces a cytokine gene transcription innate immunity repertoire. In the present study, we describe the invasiveness, morphological
Rev. Bras. Cienc. Avic.. Publicado em: 2016-03
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6. B cells expressing IL-10 mRNA modulate memory T cells after DNA-Hsp65 immunization
In DNA vaccines, the gene of interest is cloned into a bacterial plasmid that is engineered to induce protein production for long periods in eukaryotic cells. Previous research has shown that the intramuscular immunization of BALB/c mice with a naked plasmid DNA fragment encoding the Mycobacterium leprae 65-kDa heat-shock protein (pcDNA3-Hsp65) induces prote
Braz J Med Biol Res. Publicado em: 18/09/2015
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7. Papel protetor do alelo G do polimorfismo no gene Interleucina 10 (-1082G/A) contra o desenvolvimento de pré-eclâmpsia
OBJETIVOS:Identificar a frequência do polimorfismo no gene IL-10, rs1800896 (-1082 A/G), em mulheres com pré-eclâmpsia (PE) e em mulheres do grupo controle e associar a presença deste polimorfismo com a proteção contra o desenvolvimento da PE.MÉTODOS:Estudo do tipo caso-controle, no qual foram selecionadas 54 mulheres com PE, classificadas de acordo c
Rev. Bras. Ginecol. Obstet.. Publicado em: 03/10/2014
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8. Análise molecular de polimorfismos nos genes HLA-ClASSE II DRB1* e IL7R? possivelmente associados com a susceptibilidade à esclerose múltipla em uma amostra da população do Rio de Janeiro
Multiple sclerosis (MS) is an inflammatory and degenerative disease of the central nervous system (CNS) that affects mainly young adults. MS seems to be a polygenic and multifactorial disease, and genetic susceptibility has been associated mainly with the major histocompatibility complex (MHC), which in humans is the human leukocyte antigen (HLA). Among non-
Arq. Neuro-Psiquiatr.. Publicado em: 2014-06
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9. Expression of oxidative stress and antioxidant defense genes in the kidney of inbred mice after intestinal ischemia and reperfusion
PURPOSE: To determine the gene expressions profile related to the oxidative stress and the antioxidant response in the kidneys of mice subjected to intestinal ischemia and reperfusion. METHODS: Twelve inbred mice (C57BL/6) were randomly assigned to one of two groups: the control group (CG) underwent anesthesia and was observed for 120 min and the ischemia/re
Acta Cir. Bras.. Publicado em: 2013-12
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10. Keratinocyte growth factor, tumor necrosis factor-alpha and interleukin-1 beta gene expression in cultured fibroblasts and keratinocytes from burned patients
PURPOSE: To evaluate the gene expression of KGF, TNF-alpha and IL-1 beta in skin fibroblasts and keratinocytes cultured from burned patients. METHODS: Three patients with large burns and three patients with small burns, as well as two controls, were included. The cell culture was initiated by the enzymatic method. After extraction and purification of mRNA, q
Acta Cir. Bras.. Publicado em: 2013-08
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11. Papel funcional dos leucotrienos na resposta imunológica ao melanoma B16-F0 experimental em camundongos / The role of Leukotrienes in the immune response of melanoma B16-F0 in experimental mice
No presente trabalho investigamos a relevância dos mediadores lipídicos (Leucotrienos) gerados pela enzima 5-Lipoxigenase (5-LO) na susceptibilidade ou resistência de camundongos ao Melanoma experimental com células tumorais B16-F0, utilizando como modelo camundongos produtores de leucotrienos (129_WT) e camundongos geneticamente deficientes \"knockout\"
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/06/2012
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12. Expression of cytokine transcription related to Th17 and T regulatory responses in lesions of chronic periodontitis in type 2 diabetics. / Expressão de citocinas de transcrição relacionados às respostas Th17 e T regulatórias em lesões de periodontite crônica de diabéticos tipo 2.
Although diabetes mellitus (DM) is a well-recognized risk factor for periodontitis, the cellular and molecular mechanisms that link both diseases were not completely elucidated. To date, few studies have evaluated the role of T helper (Th) 17 and T regulatory (Treg) cells in diabetic subjects with chronic periodontitis (CP). Therefore, the aim of this study
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/02/2012