Fast Fashion
Mostrando 25-36 de 41 artigos, teses e dissertações.
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25. Slow excitatory synaptic potentials recorded from neurones of guinea-pig submucous plexus.
Intracellular recordings made from neurones of guinea-pig submucous plexus revealed three types of synaptic input: cholinergic excitatory synaptic potentials (fast e.p.s.p.s) of 50-80 ms duration, inhibitory synaptic potentials (i.p.s.p.s) of 1 s duration, and non-cholinergic, non-adrenergic slow e.p.s.p.s which lasted for 15-20 s. A single stimulus was suff
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26. Submillisecond folding of monomeric lambda repressor.
The folding kinetics of a truncated form of the N-terminal domain of phage lambda repressor [lambda 6-85] has been investigated by using the technique of dynamic NMR. lambda 6-85 has been shown previously to fold in a purely two-state fashion. This allows the determination of folding and unfolding rates from simulation of the exchange-broadened aromatic reso
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27. Self-assembly of a heteroduplex helicate from two different ligand strands and Cu(II) cations.
Cu(II) ions have been reacted with a 1/1 mixture of two linear ligands, one containing three 2,2'- bipyridine groups and the other three 2,2':6',2"-terpyridine groups. Absorption spectroscopy and fast atom bombardment mass spectrometry indicate the formation of a trinuclear complex containing one ligand of each kind. Determination of the crystal structure of
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28. Conditionally replicating mycobacteriophages: A system for transposon delivery to Mycobacterium tuberculosis
Transposon mutagenesis provides a direct selection for mutants and is an extremely powerful technique to analyze genetic functions in a variety of prokaryotes. Transposon mutagenesis of Mycobacterium tuberculosis has been limited in part because of the inefficiency of the delivery systems. This report describes the development of conditionally replicating sh
The National Academy of Sciences of the USA.
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29. Titanospirillum velox: A huge, speedy, sulfur-storing spirillum from Ebro Delta microbial mats
A long (20–30 μm), wide (3–5 μm) microbial-mat bacterium from the Ebro Delta (Tarragona, Spain) was grown in mixed culture and videographed live. Intracellular elemental sulfur globules and unique cell termini were observed in scanning-electron-microprobe and transmission-electron micrographs. A polar organelle underlies bundles of greater than 60 flag
The National Academy of Sciences.
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30. Vagaries of the molecular clock
The hypothesis of the molecular evolutionary clock asserts that informational macromolecules (i.e., proteins and nucleic acids) evolve at rates that are constant through time and for different lineages. The clock hypothesis has been extremely powerful for determining evolutionary events of the remote past for which the fossil and other evidence is lacki
The National Academy of Sciences of the USA.
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31. Genetic evidence on the organization and action of the qa-1 gene product: a protein regulating the induction of three enzymes in quinate catabolism in Neurospora crassa.
The first three reactions in the catabolism of qainic acid in Neurospora crassa are under the genetic control of the qa gene cluster. This cluster consists of three structural genes encoding three inducible enzymes plus a regulatory gene (qa-1+) whose diffusible product apparently acts in a positive fashion to initiate coordinate synthesis of the three enzym
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32. Effects of 2,3-butanedione monoxime on the contractile activation properties of fast- and slow-twitch rat muscle fibres.
1. The effects of 2,3-butanedione monoxime (BDM, 0.2-10 mmol/l) have been examined at different temperatures on calcium transients (measured with aequorin) and isometric force in intact bundles of fibres from soleus (slow-twitch) and extensor digitorum longus (EDL; fast-twitch) muscles of the rat and on Ca2+-activated isometric force of mechanically skinned
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33. Simulation of integrin-cytoskeletal interactions in migrating fibroblasts.
Cell migration is a dynamic phenomenon requiring a physical interaction between the internal cell motile machinery and the external substratum in which adhesion receptors, such as integrins, serve as the transmembrane link. To analyze quantitatively this interaction, we apply a modified Brownian dynamics algorithm to simulate cytoskeleton-mediated transport
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34. Ultrastructure of Rickettsia rickettsii Actin Tails and Localization of Cytoskeletal Proteins
Actin-based motility (ABM) is a mechanism for intercellular spread that is utilized by vaccinia virus and the invasive bacteria within the genera Rickettsia, Listeria, and Shigella. Within the Rickettsia, ABM is confined to members of the spotted fever group (SFG), such as Rickettsia rickettsii, the agent of Rocky Mountain spotted fever. Infection by each ag
American Society for Microbiology.
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35. Activation of myoD gene transcription by 3,5,3'-triiodo-L-thyronine: a direct role for the thyroid hormone and retinoid X receptors.
Thyroid hormones are major determinants of skeletal muscle differentiation in vivo. Triiodo-L-thyronine treatment promotes terminal muscle differentiation and results in increased MyoD gene transcription in myogenic cell lines; furthermore myoD and fast myosin heavy chain gene expression are activated in rodent slow twitch muscle fibers (Molecular Endocrinol
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36. Kinetic analysis of the phosphorylation-dependent interactions of synapsin I with rat brain synaptic vesicles.
1. Synapsin I, a major synaptic vesicle (SV)-associated phosphoprotein, is involved in the regulation of neurotransmitter release and synapse formation. By binding to both phospholipid and protein components of SV with high affinity and in a phosphorylation-dependent fashion, synapsin I is believed to cluster SV and to attach them to the actin-based cytoskel