Disease Complexes
Mostrando 13-24 de 510 artigos, teses e dissertações.
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13. Skeletal muscle major histocompatibility complex class I and II expression differences in adult and juvenile dermatomyositis
OBJECTIVE: To analyze major histocompatibility complex expression in the muscle fibers of juvenile and adult dermatomyositis. METHOD: In total, 28 untreated adult dermatomyositis patients, 28 juvenile dermatomyositis patients (Bohan and Peter's criteria) and a control group consisting of four dystrophic and five Pompe's disease patients were analyzed. Routin
Clinics. Publicado em: 2012-08
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14. Complexos do tipo cis-[Ru(L-phen)2(apy)2]2+ com interesse no tratamento de Mal de Alzheimer: propriedades físico-químicas e estudos de inibição da Acetilcolina Esterase / Cis-[Ru(L-phen)2(apy)2]2+ complexes, with interest in the treatment of alzheimer‟s disease: physicochemical properties and acetylcholinesterase enzyme inhibition
No seguinte trabalho está relatado a síntese, caracterização e propriedades fotoquímicas e fotofísicas do complexo cis-[Ru(phen)2(4apy)2]2+ em que 4apy = 4- aminopiridina. Este complexo é termicamente estável em solução aquosa ou mesmo em solventes orgânicos, o espectro de absorção desta espécie é caracterizado por uma banda intensa em 450 nm,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/04/2011
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15. SYNTHESIS AND CHARACTERIZATION OF BINUCLEATING LIGANDS DERIVED FROM THE ISONIAZID AND THEIR DINUCLEAR COPPER(II) COMPLEXES / SÍNTESE E CARACTERIZAÇÃO DE LIGANTES BINUCLEANTES DERIVADOS DA ISONIAZIDA E SEUS COMPLEXOS BINUCLEARES DE COBRE (II)
Considering the limitations and undesirable side effects observed in cancer therapy with platinum derivatives, many efforts have been made with the aim of obtaining new drugs more effective and less toxic, able to promote the hydrolytic cleavage or oxidative DNA chain other subcellular structures critical. Until now, some copper complexes have been developed
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/02/2011
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16. The need to carry out re-inventory of plant pathogenic fungi
Plant pathogenic fungi have long been documented through concerted efforts of mycologists and plant pathologists; these records have served as the basis for regional and countrywide checklists which have since been put into databases listing hosts and associated fungi. They are used by governments and scientists to formulate trade quarantine policies and det
Tropical Plant Pathology. Publicado em: 2011-08
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17. Comparison of dot-ELISA and standard ELISA for detection of Neisseria meningitidis outer membrane complex-specific antibodies
Dot-ELISA using the outer membrane complex antigens of Neisseria meningitidis as a target was standardized for rapid detection of meningococcal-specific antibodies in human serum. We investigated the level of meningococcal-specific IgG, IgA, and IgM in serum using dot-ELISA with outer membrane antigens prepared from Neisseria meningitidis serotype B:4.19:P1.
Brazilian Journal of Infectious Diseases. Publicado em: 2010-02
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18. SÍNTESE E CARACTERIZAÇÃO DE COMPLEXOS DE COBRE (II) E ZINCO (II) COM DIPEPTÍDEOS DE INTERESSE BIOLÓGICO / SYTHESIS AND CHARACTERIZATION OF COPPER (II) AND ZINC (II) COMPLEXES WITH DIPEPTIDES OF BIOLOGICAL INTEREST
This work describes the synthesis and characterization of copper (II) and zinc (II) complexes, with dipeptides in solid state. The dipeptides involved were: glycyl-glycine, glycyl-valine, methionyl-methionine, methionyl-glycine and cysteinyl-glycine, whose aminoacids take part in some proteins involved in neurodegeneration processes, more specifically in Alz
Publicado em: 2010
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19. SÍNTESE E CARACTERIZAÇÃO DE COMPLEXOS DE PLATINA COM LIGANTES DIAMINADOS N-ALQUILADOS DE CADEIA LONGA CONTENDO UM GRUPO HIDROXILA
Cancer is considered one of the main causes of death around the world. This disease can be treated using radiotherapy, surgery, and chemotherapy. Since the discovery of the anticancer activity of cisplatin, studies involving the use of metal complexes as drugs have grown substantially. Aiming to improve the spectrum of antitumor activity, to decrease side ef
Publicado em: 2010
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20. Epidemiologia da leishmaniose visceral humana em Araguaína (TO) e o diagnóstico sorológico da doença / Epidemiology of human visceral Leishmaniasis in Araguaína (TO) and serological diagnosis of this disease
Human visceral leishmaniasis (HVL) is a severe systemic protozoonosis that has presented changes at the epidemiological behavior, with a growing trend in Brazil. It has been conducted a cross sectional study to assess the context of HVL in the city of Araguaina (TO) from January 2007 to August 2010. Additionally, tests were conducted to compare the diagnosti
Publicado em: 2010
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21. Ureases display biological effects independent of enzymatic activity. Is there a connection to diseases caused by urease-producing bacteria?
Ureases are enzymes from plants, fungi and bacteria that catalyze the hydrolysis of urea to form ammonia and carbon dioxide. While fungal and plant ureases are homo-oligomers of 90-kDa subunits, bacterial ureases are multimers of two or three subunit complexes. We showed that some isoforms of jack bean urease, canatoxin and the classical urease, bind to glyc
Publicado em: 2010
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22. SYNTHESIS AND CHARACTERIZATION OF COMPOUNDS FORMED BETWEEN CISPLATINUM AND GLUTATHIONE OR PENICILLAMINE LIGANDS / SÍNTESE E CARACTERIZAÇÃO DE COMPOSTOS FORMADOS ENTRE A CISPLATINA E OS LIGANTES GLUTATIONA OU PENICILAMINA
Cisplatinum is considered an important chemotherapeutic drug used against some kinds of cancer. However, the use of this drug may cause side effects such as ototoxicity, neurotoxicity and, mainly, nephrotoxicity. This fact has been related to the interaction of cisplatinum with biomolecules containing sulfur, such as proteins and amino acids. To promote the
Publicado em: 2010
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23. Molecular studies of Anopheles albitarsis and Anopheles triannulatus (Diptera: Culicidae) captured in flood plain breeding sites in Mato Grosso do Sul, Brazil / Estudos moleculares de Anopheles albitarsis e Anopheles triannulatus (Diptera: Culicidae) capturados em criadouro na planície de inundação do Mato Grosso do Sul, Brasil
Malaria is a severe disease whose vectors are mosquitoes belonging to the genus Anopheles. This genus contains 500 species of which approximately 45 are responsible for the worldwide transmission of these parasites. Some of these vectors belong to cryptic species such as those of the Albitarsis and Triannulatus Complex. The Albitarsis Complex is composed of
Publicado em: 2010
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24. Efeito isolado e combinado de Pratylenchus brachyurus e Fusarium verticillioides no desenvolvimento de dois híbridos de milho
O objetivo deste estudo foi avaliar o efeito de Pratylenchus brachyurus e/ou Fusarium verticillioides e sua relação no desenvolvimento de dois híbridos de milho (30F80 e 30K73). O experimento foi conduzido em casa de vegetação no Centro de Pesquisa da Pioneer Sementes de Itumbiara-GO. O delineamento experimental foi inteiramente ao acaso com 15 tratamen
Publicado em: 2010