Developmental Programming
Mostrando 1-12 de 20 artigos, teses e dissertações.
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1. Nutrition and Cardiovascular Diseases: Programming and Reprogramming
Abstract The Developmental Origin of Health and Disease (DOHaD) is an area of science dedicated to studying the processes by which insults during critical periods of mammals development leading to physiological changes resultig in diseases throughout life. Studies point to a complex interaction between nutritional status in early life and cardiovascular syst
Int. J. Cardiovasc. Sci.. Publicado em: 2021-04
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2. Hormonal Biomarkers for Evaluating the Impact of Fetal Growth Restriction on the Development of Chronic Adult Disease
Resumo A hipótese das origens fetais de doenças em adultos propõe que distúrbios crônicos metabólicos, incluindo doenças cardiovasculares, diabetes e hipertensão, se originam na plasticidade do desenvolvimento devido a insultos intrauterinos. Estes processos envolvem uma resposta adaptativa do feto amudanças nos sinais ambientais que podem promover
Rev. Bras. Ginecol. Obstet.. Publicado em: 19/06/2019
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3. Cardio-respiratory development in bird embryos: new insights from a venerable animal model
ABSTRACT The avian embryo is a time-honored animal model for understanding vertebrate development. A key area of extensive study using bird embryos centers on developmental phenotypic plasticity of the cardio-respiratory system and how its normal development can be affected by abiotic factors such as temperature and oxygen availability. Through the investiga
R. Bras. Zootec.. Publicado em: 2016-11
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4. Estudo das alterações cardiovasculares e metabólicas em modelo experimental de programação metabólica: efeito de extrato da casca de uva Vitis vinífera / Study of cardiovascular and metabolic alterations in experimental model of metabolic programming: effect of extract from skin of grape extract of grape Vitis vinifera
Epidemiological and experimental studies have suggested that cardiovascular risk factors can be partly attributed to the influences of the environment in which the individual lives, and that maternal nutrition influences the programming of metabolic and cardiovascular diseases in adults characterizing the metabolic syndrome. On the other hand, previous studi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/03/2011
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5. Perfil bioquímico e proteômico do recém nascido pequeno para a idade gestacional: pesquisa de biomarcadores para hipertensão arterial na vida adulta. / Biochemical and proteomic profile of newborns small for gestational age: search for biomarkers for hypertension in adulthood.
Introduction: systemic arterial hypertension is a serious public health problem. A strong correlation between birthweight and mortality and morbidity from hypertension and cardiovascular disease formed the basis for the fetal programming hypothesis for the non communicable diseases of adulthood; also known as Barkers hypothesis of hypothesis of the developme
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/03/2011
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6. Karyoplast exchange between strontium- and 6-DMAP-parthenogenetically activated zygotes of cattle.
Ooplasmic factors drive nuclear organization after fertilization and are also important for re-programming in nuclear transfer procedures, in which artificial activation is essential for reconstructed embryos to progress in development. The present research evaluated the effect of pronuclear transfer (PT) between zygotes parthenogenetically activated with io
Animal Reproduction Science. Publicado em: 2011
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7. Neonatal overfeeding leads to developmental programming of adult obesity: you are what you ate
Blackwell Science Inc.
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8. The importance of altered gene promoter methylation and transcription factor binding in developmental programming of central appetitive drive
Blackwell Science Inc.
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9. Hypermethylation of Homeobox A10 by in Utero Diethylstilbestrol Exposure: An Epigenetic Mechanism for Altered Developmental Programming
Diethylstilbestrol (DES) is a nonsteroidal estrogen that induces developmental anomalies of the female reproductive tract. The homeobox gene HOXA10 controls uterine organogenesis, and its expression is altered after in utero DES exposure. We hypothesized that an epigenetic mechanism underlies DES-mediated alterations in HOXA10 expression. We analyzed the exp
The Endocrine Society.
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10. Resonating circadian clocks enhance fitness in cyanobacteria
In some organisms longevity, growth, and developmental rate are improved when they are maintained on a light/dark cycle, the period of which “resonates” optimally with the period of the endogenous circadian clock. However, to our knowledge no studies have demonstrated that reproductive fitness per se is improved by resonance between the endogenous clock
The National Academy of Sciences.
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11. Hypoxanthine-guanine phosphoribosyl transferase regulates early developmental programming of dopamine neurons: implications for Lesch-Nyhan disease pathogenesis
Hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency results in Lesch-Nyhan disease (LND), where affected individuals exhibit a characteristic neurobehavioral disorder that has been linked with dysfunction of dopaminergic pathways of the basal ganglia. Since the functions of HPRT, a housekeeping enzyme responsible for recycling purines, have no d
Oxford University Press.
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12. RNA-Mediated Programming of Developmental Genome Rearrangements in Paramecium tetraurelia
The germ line genome of ciliates is extensively rearranged during development of the somatic macronucleus. Numerous sequences are eliminated, while others are amplified to a high ploidy level. In the Paramecium aurelia group of species, transformation of the maternal macronucleus with transgenes at high copy numbers can induce the deletion of homologous gene
American Society for Microbiology.