Conjugation
Mostrando 1-12 de 1580 artigos, teses e dissertações.
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1. Using static, kinetic and metal mobility procedures to evaluate possibilities of coal waste land disposal at Moatize Mine, Mozambique
Abstract Coal mine waste rocks produced during mining and beneficiation can affect the environment due to land degradation and acid mine drainage generation. However, proper characterization and treatment of mineral processing wastes creates options for safe disposal, enhancing the environmental performance. The aim of this study was to use static and kineti
REM, Int. Eng. J.. Publicado em: 2020-12
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2. Synthesis of 1,2,3-Triazole Derivatives of Hydnocarpic Acid Isolated from Carpotroche brasiliensis Seed Oil and Evaluation of Antiproliferative Activity
Carpotroche brasiliensis is a tree native to Brazil, belonging to the family Flacurtiaceae, whose seeds contain a group of cyclopentenyl fatty acids: gorlic (12%), chaulmugric (27%), and hydnocarpic (48.7%). These compounds are considered the main therapeutic agents in the treatment of leprosy. In the present study, a series of novel triazole compounds were
J. Braz. Chem. Soc.. Publicado em: 2020-12
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3. Engineered scPDL1-DM1 drug conjugate with improved in vitro analysis to target PD-L1 positive cancer cells and intracellular trafficking studies in cancer therapy
Abstract Antibody-drug conjugates (ADC), precisely deliver a cytotoxic agent to antigen-expressing tumor cells by using specific binding strategies of antibodies. The ADC has shown the ability of potent bio-therapeutics development but indefinite stoichiometric linkage and full-length antibody penetration compromised the field of its advancement. Single chai
Genet. Mol. Biol.. Publicado em: 17/01/2020
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4. EFEITOS DA TEMPERATURA NOS ESPECTROS RAMAN DOS POLÍMEROS CONDUTORES PEDOT E MEH-PPV
The present work shows the temperature dependence of the Raman spectra of two conjugated polymers: poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) and poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS). In situ resonance Raman spectra of PEDOT from 77 to 423 K at 633 nm and of MEH-PPV from 77 to 473 K at 785 nm suggest th
Quím. Nova. Publicado em: 05/12/2019
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5. ESQUARAÍNAS CIS E TRANS SUBSTITUÍDAS: APLICAÇÃO EXPERIMENTAL DA TEORIA DE GRUPO EM ESPECTROSCOPIA VIBRACIONAL
This work shows a practical application of the group theory to a relatively simple molecular system, as well its impact in the results obtained through vibrational spectroscopic techniques. Squaraines substituted by dicyanemethylene groups have been extensively studied, and after minor approaches in the sense to facilitate the point group determination, they
Quím. Nova. Publicado em: 05/12/2019
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6. (Bio)conjugation Strategies Applied to Fluorescent Semiconductor Quantum Dots
Quantum dots (QDs) are semiconductor nanocrystals, which present unique photophysical properties, enabling their application as new fluorescent platforms for biomedical sciences. Colloidal QDs are end-capped with organic or inorganic compounds, not only to prevent their agglomeration but also to provide reaction sites for the attachment of targeting (bio)mol
J. Braz. Chem. Soc.. Publicado em: 24/10/2019
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7. Genetic analysis of the first mcr-1 positive Escherichia coli isolate collected from an outpatient in Chile
ABSTRACT Global dissemination of mcr-like genes represents a serious threat to public health since it jeopardizes the effectiveness of colistin, an antibiotic used as a last-resort treatment against highly antibiotic-resistant bacteria. In 2017, a mcr-1-positive isolate of Escherichia coli was found in Chile for the first time. Herein we report the genetic f
Braz J Infect Dis. Publicado em: 09/09/2019
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8. Fatores de contextualização em textos redigidos por um estudante surdo
Resumo O trabalho tem como objetivo analisar o percurso de aprendizagem de escrita de um aluno surdo a partir de atividades realizadas em uma oficina de redação em Língua Portuguesa, ministrada por um professor ouvinte. Questões: 1) Como um estudante surdo administra, em seus escritos, os fatores de contextualização, elementos que ancoram o texto em um
Pro-Posições. Publicado em: 04/07/2019
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9. Protein PEGylation for the design of biobetters: from reaction to purification processes
The covalent attachment of polyethylene glycol (PEG) to therapeutical proteins is an important route to develop biobetters for biomedical, biotech and pharmaceutical industries. PEG conjugation can shield antigenic epitopes of the protein, reduce degradation by proteolytic enzymes, enhance long-term stability and maintain or even improve pharmacokinetic and
Braz. J. Pharm. Sci.. Publicado em: 08/11/2018
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10. Influence of solvent used on oxidative polymerization of Poly(3-hexylthiophene) in their chemical properties
Abstract The aim of the study is to utilize the simplicity of oxidative polymerization with ferric chloride to originates poly(3-hexylthiophene) of lower molecular weight. So, the chloroform, in general used as solvent in this synthesis, was switched by dichloromethane. The obtained polymers were characterized by infrared spectroscopy (FTIR), ultra-violet v
Polímeros. Publicado em: 21/09/2018
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11. Study of pandrug and heavy metal resistance among E. coli from anthropogenically influenced Delhi stretch of river Yamuna
Abstract Escalating burden of antibiotic resistance that has reached new heights present a grave concern to mankind. As the problem is no longer confined to clinics, we hereby report identification of a pandrug resistant Escherichia coli isolate from heavily polluted Delhi stretch of river Yamuna, India. E. coli MRC11 was found sensitive only to tobramycin a
Braz. J. Microbiol.. Publicado em: 2018-09
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12. Development of radioimmunoconjugate for diagnosis and management of head-and-neck subclinical cancer and colorectal carcinoma
ABSTRACT Scientific innovations in diagnostic methods are important drivers of cancer control and prevention. Noninvasive imaging of the epidermal growth factor receptor (EGFR) in head-and-neck squamous, cell carcinoma and colorectal cancer could be valuable to select patients for EGFR-targeted therapy, as well as to monitor the efficacy and occurrence of re
Braz. J. Pharm. Sci.. Publicado em: 09/04/2018