Computational Biology
Mostrando 13-24 de 110 artigos, teses e dissertações.
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13. Análise qualitativa de riscos de projetos suportada pela teoria dos jogos / Project risk assessment supported by game theory
Since 1944, when it was published the first book by John Von Neumann about Game Theory, the application field is growing very fast year after year. At the begin the theory was widely used to predict Macroeconomics behavior but nowadays there are several studies in different areas as biology, sociology and computational engineering. John Maynard Smith in the
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/12/2010
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14. Protein structure comparison via contact map alignment / Protein structure comparison via contact map alignment
Proteins are primary components in almost all biological processes in living organisms. It is known that the variety of protein functions is a result of the differences in protein structures. Therefore, understanding and comparing the structure of proteins is a major challenge in modern molecular biology. The structural alignment and comparison of proteins b
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/02/2010
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15. Enumeração de traces e identificação de breakpoints : estudo de aspectos da evolução / Enumeration of traces and breakpoint identification : study of evolutionary aspects
O estudo de rearranjo de genomas tem o objetivo de auxiliar o entendimento da evolução. Através da análise dos eventos de mutação como inversões, transposições, fissões, fusões, entre outros, buscamos compreender as suas influências sobre o fenômeno da diferenciação das espécies. Dentro deste contexto, esta tese ataca dois temas distintos: a
Publicado em: 2010
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16. Actin-interacting and flagellar proteins in Leishmania spp.: bioinformatics predictions to functional assignments in phagosome formation
Several motile processes are responsible for the movement of proteins into and within the flagellar membrane, but little is known about the process by which specific proteins (either actin-associated or not) are targeted to protozoan flagellar membranes. Actin is a major cytoskeleton protein, while polymerization and depolymerization of parasite actin and ac
Genetics and Molecular Biology. Publicado em: 2009
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17. Polimorfismos dos genes HLA e regiões promotoras do TNF- alfa -238 e -308 como fatores de sucetibilidade a psoriase e gravidade da doença / HLA and TNF-Alpha promoter regions -238 and -308 polymorphisms and marks of susceptibility to psoriasis and severety of the disease
Psoriasis is an erythematous, scaly inflammatory dermatosis with a complex immunologic basis. The strongest genetic marker for psoriasis is HLA-Cw*06. Polymorphisms in the TNF-a promoter region, especially replacement of guanine with adenine in positions -238 and -308 are related to higher TNF-a production and higher risk for psoriasis in Caucasoid populatio
Publicado em: 2009
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18. Uso de técnicas computacionais no estudo da transcrição e regulação gênica em Homo sapiens e Mus musculus / Use of computational methods to study the transcription and gene regulation in Homo sapiens and Mus musculus
Genes, nucleotide sequences necessary for the synthesis of functional molecules, are transcribed and regulated by extremely complex cellular and molecular processes. To understand when and in which tissues the genes are expressed, their functional isoforms, control regions and the factors involved in gene regulation is one of major challenges of modern molec
Publicado em: 2008
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19. SimAffling um ambiente computacional para suporte e simulação do processo de DNA shuffling
The Molecular Evolution of the living organisms is a slow process that occurs over the years producing mutations and recombinations at the genetic material, i.e. at the DNA. The mutations can occur as nucleotide remotion, insertion and/or substitution at the DNA chain. The Directed Molecular Evolution is an in vitro process that tries to improve biological f
Publicado em: 2008
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20. Uma abordagem de metodos computacionais para simulação de processos biologicos : simulação tridimensional e metabolica do desenvolvimento tumoral / A computational approach for simulation of biological process : tridimensional simulation of tumor metabolism and development
In this work, we created a piece of software and computer models for studying carcinogenesis, in order to answer biological questions related to the treatment of this disease. The computer models were inspired in the theory of Somatic Evolution and Acid Mediated Tumor Invasion, proposed by Gatenby and Gillies, and were implemented in a tool developed by the
Publicado em: 2008
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21. Helly property, clique graphs, complementary graph classes, and sandwich problems
A sandwich problem for property Π asks whether there exists a sandwich graph of a given pair of graphs which has the desired property Π. Graph sandwich problems were first defined in the context of Computational Biology as natural generalizations of recognition problems. We contribute to the study of the complexity of graph sandwich problems by considering
Journal of the Brazilian Computer Society. Publicado em: 2008
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22. Detecção Automática de Ondas de Elliott em Mercado Acionário / Automatic Identification of Elliott Waves in Stocks Market
The Elliott Wave analysis is a technique developed for the prediction of prices of financial assets (stocks, exchange rates etc.). This work introduces the basic concepts of the financial market, focusing mainly on the Elliott Wave principle, which differs from other techniques for providing direction and intensity of changes in shares / stocks prices in the
Publicado em: 2008
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23. Aprendizado semi-supervisionado e não supervisionado para análise de dados de expressão gênica
Data clustering has been seen, in the last decades, as an important tool for gene expression data analysis. In recent years, due to the progress in gene annotation research, a growing interest has been noticed for the semi-supervised clustering techniques, which use knowledge previously available about some gene functions to discover functions of other genes
Publicado em: 2008
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24. Computational methods applied to the genomes of the mycobacteria and trypanosomatids: of the assembly to the notation. / Abordagens computacionais aplicadas aos genomas de micobactérias e Trypanossomatídeos : da montagem à anotação.
Esta dissertação trata do desenvolvimento de novas abordagens e ferramentas computacionais focadas nas seguintes aplicações: aperfeiçoamento do fluxo de informação de Plataformas Tecnológicas de Seqüenciamento e de Bioinformática; montagem de seqüências em projetos genomas; detecção de seqüências repetitivas; análise comparativa e anotação
Publicado em: 2008