Cd10 And Cd19 Antigens
Mostrando 1-12 de 27 artigos, teses e dissertações.
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1. Estudo da expressão de Antígenos Aberrantes em plasmócitos de portadores de Mieloma Múltiplo através de Citometria de Fluxo Mul-tiparamétrica / Detection of aberrant antigens in multiple myeloma cells by multiparametric flow cytometry.
The aims of this study were to determine aberrant antigens (AA) in MM cells and to evaluate their prognostic value and frequency. Methods : bone marrow plasma cells of an homogeneous cohort of 30 newly diagnosed patients with MM were studied. As normal control, bone marrow plasma cells from 4 healthy marrow do-nors were also evaluated. Surface and cytoplasmi
Publicado em: 2006
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2. AnÃlise comparativa em histograma da intensidade de fluorescÃncia de CD10 e CD19 em blastos leucÃmicos e hematogÃnias / Comparative analysis carried out through histograms of CD10 and CD19 fluorescence intensity in leukemic blasts and hematogones
Hematogones are normal immature cells from bone marrow that are responsible for the production of the immune systemâs B cell lineage. The acute lymphoblastic leukemia (ALL) of precursors B cells represents one type of neoplastic transformation of hematogones. Due to their high similarity there are risks of erroneous interpretation consequently making it nec
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/06/2005
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3. CD19 and immunophenotype of bone marrow plasma cells in monoclonal gammopathy of undetermined significance.
AIMS--To determine whether a particular phenotype or antigen is preferentially related to monoclonal gammopathies of undetermined significance (MGUS). METHODS--Bone marrow specimens from 56 patients with MGUS were stained immunocytochemically (ABC peroxidase) for CD38, CD56, CD9, CD10, CD19, CD20, CD22, and MB2. Specimens from patients recently diagnosed wit
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4. Immunobiologic differences between normal and leukemic human B-cell precursors.
The early stages of normal human B-cell differentiation were studied by flow cytometry and cell sorting based on expression of CD10 (CALLA) and CD19 antigens in fetal liver. Both CD10+ CD19+ and CD10+ CD19- precursor populations proliferated in vitro to form B-cell precursor colonies under stimulation from low molecular weight B-cell growth factor (L-BCGF) o
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5. Multiparametric immunophenotyping of B cells in peripheral blood of healthy adults by flow cytometry.
The investigation of patients suffering from malignant lymphomas of the B-cell type requires flow cytometric immunophenotyping. Several reports described the expression of almost all B lineage antigens on normal and abnormal B lymphocytes. Thus, immunophenotyping of lymphomas must be interpreted in the context of the reference values obtained for healthy con
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6. The skin homing receptor cutaneous leucocyte-associated antigen (CLA) is up-regulated by Leishmania antigens in T lymphocytes during active cutaneous leishmaniasis
The cutaneous leucocyte-associated antigen receptor (CLA) can direct Leishmania-specific T lymphocytes towards inflamed skin lesions. Homing receptors [CLA, lymphocyte-associated antigen 1 (LFA-1) or CD62L] were analysed in lymphocytes from blood and cutaneous leishmaniasis (CL) lesions. CL patients with active lesions (A-CL) presented lower levels of T lymp
Blackwell Science Inc.
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7. Identification of malignant plasma cell precursors in the bone marrow of multiple myeloma.
Precursors of plasma cells were studied in the bone marrow of 28 patients with multiple myeloma, plasma cell leukemia, and benign monoclonal gammopathy. Pre-B and B cell populations were analyzed with anti-B monoclonal antibodies corresponding to the clusters standardized at the Leucocyte Typing Workshops in Paris and Boston (CD9, CD10, CD19-22, CD24). In ad
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8. Immunological and ultrastructural studies in acute biphenotypic leukaemia.
AIMS--To compare the sensitivity of the ultrastructural method to detect myeloperoxidase (MPO) with light microscopy and immunocytochemistry using an anti-MPO antibody; to examine the expression of lymphoid antigens in relation to MPO activity in blast cells from cases of biphenotypic leukaemia. METHODS--Blast cells from 14 cases of biphenotypic acute leukae
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9. Immunophenotyping of acute lymphoblastic leukaemia in routinely processed bone marrow biopsy specimens.
AIMS: To assess the value of immunophenotyping of acute lymphoblastic leukaemia (ALL) in routinely processed bone marrow trephine biopsy specimens and to establish a minimum panel of antibodies to assess lymphoid lineage and enable differentiation from acute myeloid leukaemia. METHODS: 45 routinely processed bone marrow biopsy specimens (formalin fixed, para
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10. Fas Ligand-Expressing B-1a Lymphocytes Mediate CD4+-T-Cell Apoptosis during Schistosomal Infection: Induction by Interleukin 4 (IL-4) and IL-10
A previous study of the murine model of Schistosoma mansoni infection has implicated splenic CD19+ B lymphocytes as Fas ligand (FasL)-bearing mediators of CD4+ T-lymphocyte apoptosis. The present study shows that B-cell deficiency leads to decreased CD4+ T-cell apoptosis during infection and compares FasL expression and killer function of B-1a- and CD5− B-
American Society for Microbiology.
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11. Configuration of immunoglobulin and T cell receptor beta and gamma genes in acute myeloid leukaemia: pitfalls in the analysis of 40 cases.
AIMS: To evaluate the overall incidence of immunoglobulin (Ig) and T cell receptor (TCR) beta and gamma gene rearrangements in a series of 40 cases of acute myeloid leukaemia (AML) and to determine whether structural modifications of these genes could be correlated with the abnormal expression of lymphoid markers in malignant cells. METHODS: All cases were c
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12. Cytokine Induction by Streptococcus mutans and Pulpal Pathogenesis
Chronic pulpal inflammation under caries appears to be elicited by bacterial antigens that diffuse into the pulp through dentinal tubules. This prompted the hypothesis that cytokines elicited by antigens from Streptococcus mutans, which frequently dominates shallow lesions, could play a major role in eliciting the initial T-cell response in the pulp. To test
American Society for Microbiology.