Bone Marrow
Mostrando 13-24 de 3900 artigos, teses e dissertações.
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13. Do cytomegalovirus infections affect the daratumumab treatment course in multiple myeloma patients? - Literature review
ABSTRACT Introduction Multiple myeloma is a progressive and incurable hematological disease characterized by disordered and clonal multiplication of plasmacytes in the bone marrow. The main clinical manifestations are caused by the presence of neoplastic cells in bone tissue, as well as the excessive production of immunoglobulins and normal humoral immunity
Hematol., Transfus. Cell Ther.. Publicado em: 2021-06
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14. Evaluation of risk stratification strategies in pediatric patients with febrile neutropenia
Abstract Objective To evaluate the performance of risk stratification protocols for febrile neutropenia specific to the pediatric population. Methods Retrospective study of a cohort of pediatric patients undergoing cancer treatment with episodes of neutropenia due to chemotherapy and fever, treated at the emergency department of a tertiary cancer hospital
J. Pediatr. (Rio J.). Publicado em: 2021-06
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15. COVID-19 and adult acute lymphoblastic leukemia: Presentation and management
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common malignancy in children characterized by the overproduction and accumulation of immature lymphoid cells in the bone marrow and peripheral blood. The BMI-1 is an important component of the Polycomb Repressive Complex-1 (PRC1). It is an important molecule for the self-renewal of hematopo
Hematol., Transfus. Cell Ther.. Publicado em: 2021-06
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16. Utility of BMI-1 and NANOG expression levels in survival prediction of pediatric acute lymphoblastic leukemia
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common malignancy in children characterized by the overproduction and accumulation of immature lymphoid cells in the bone marrow and peripheral blood. The BMI-1 is an important component of the Polycomb Repressive Complex-1 (PRC1). It is an important molecule for the self-renewal of hematopo
Hematol., Transfus. Cell Ther.. Publicado em: 2021-06
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17. Envolvimento ósseo na doença de Gaucher: extensão do acometimento ósseo, volume esplênico e qualidade de vida
Resumo Objetivo: Investigar a correlação entre a extensão do envolvimento ósseo, o volume esplênico e a qualidade de vida em pacientes com doença de Gaucher. Materiais e Métodos: Estudo descritivo, prospectivo e transversal de 18 pacientes com doença de Gaucher submetidos a ressonância magnética de 3-T de ambos os fêmures e da coluna lombar. An�
Radiol Bras. Publicado em: 2021-04
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18. A review of hematopoietic stem cell transplantation for autoimmune diseases: multiple sclerosis, systemic sclerosis and Crohn's disease. Position paper of the Brazilian Society of Bone Marrow Transplantation
ABSTRACT Autoimmune diseases are an important field for the development of bone marrow transplantation, or hematopoietic stem cell transplantation. In Europe alone, almost 3000 procedures have been registered so far. The Brazilian Society for Bone Marrow Transplantation (Sociedade Brasileira de Transplantes de Medula Óssea) organized consensus meetings for
Hematol., Transfus. Cell Ther.. Publicado em: 2021-03
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19. Acute chest syndrome and COVID-19 in sickle cell disease pediatric patients
ABSTRACT Autoimmune diseases are an important field for the development of bone marrow transplantation, or hematopoietic stem cell transplantation. In Europe alone, almost 3000 procedures have been registered so far. The Brazilian Society for Bone Marrow Transplantation (Sociedade Brasileira de Transplantes de Medula Óssea) organized consensus meetings for
Hematol., Transfus. Cell Ther.. Publicado em: 2021-03
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20. Ultraconserved long non-coding RNA uc.112 is highly expressed in childhood T versus B-cell acute lymphoblastic leukemia
ABSTRACT Aberrant expression of long non-coding RNAs (lncRNAs) has been detected in several types of cancer, including acute lymphoblastic leukemia (ALL), but lncRNA mapped on transcribed ultraconserved regions (T-UCRs) are little explored. The T-UCRs uc.112, uc.122, uc.160 and uc.262 were evaluated by quantitative real-time PCR in bone marrow samples from c
Hematol., Transfus. Cell Ther.. Publicado em: 2021-03
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21. 5-Azacytidine restores interleukin 6-increased production in mesenchymal stromal cells from myelodysplastic patients
ABSTRACT Introduction: Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematological diseases. In addition to defects in hematologic progenitor and stem cells, dysfunctions in the bone marrow microenvironment (BMM) participate in the MDS pathogenesis. Furthermore, the immune response is deregulated by the pro-inflammatory response prevai
Hematol., Transfus. Cell Ther.. Publicado em: 2021-03
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22. Disseminated fusariosis in a patient with bone marrow aplasia,
Abstract Fusariosis is a superficial or systemic infection, which occurs mainly in immunocompromised hosts, especially in patients with hematological neoplasia; 70%–75% of the cases present cutaneous manifestations. The disseminated form is rare and difficult to diagnose; even with specific treatment, the evolution is usually fatal. Currently, it is consid
An. Bras. Dermatol.. Publicado em: 2020-10
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23. Multisystemic fusariosis with fulminant evolution,
Abstract This report presents the case of a 13-year-old female patient with history of acute myeloid leukemia, who, after a bone marrow transplant, began to vomit and experienced rapidly progressive deterioration of consciousness, in addition to disseminated erythematous-violaceous macules, and some blisters with hemorrhagic content inside. Skin biopsy evide
An. Bras. Dermatol.. Publicado em: 2020-10
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24. Current treatment preferences in acute myeloid leukemia: a survey in Brazil
ABSTRACT Introduction:: Most adults with acute myeloid leukemia (AML) will eventually relapse from their disease. The combination of 7-day cytarabine and an anthracycline on days 1-3 (the so called “7 + 3” regimen) can be considered standard of care of younger patients with AML. However, the treatment of the elderly ineligible for intensive chemotherapy
Hematol., Transfus. Cell Ther.. Publicado em: 2020-09