Disseminated fusariosis in a patient with bone marrow aplasia,

AUTOR(ES)

Chagas, Danielle Ferreira; Diniz, Lucia Martins; Lucas, Elton Almeida; Nogueira, Paulo Sergio Emerich

FONTE

An. Bras. Dermatol.

DATA DE PUBLICAÇÃO

2020-10

RESUMO

Abstract Fusariosis is a superficial or systemic infection, which occurs mainly in immunocompromised hosts, especially in patients with hematological neoplasia; 70%–75% of the cases present cutaneous manifestations. The disseminated form is rare and difficult to diagnose; even with specific treatment, the evolution is usually fatal. Currently, it is considered an emerging disease; in some centers, it is the second most common cause of invasive mycosis, after aspergillosis. The authors describe a case of a female patient with idiopathic bone marrow aplasia and disseminated fusariosis, who initially appeared to benefit from voriconazole and amphotericin B; however, due to persistent neutropenia, her clinical condition deteriorated with fatal evolution.

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