Phytochemical study of the NortheastÂs plants: Amnona squamosa Obtaining derivatives reaction of kaurenoic acid / Estudo fitoquÃmico de plantas do Nordeste: Amnona squamosa ObtenÃÃo de Derivados Reacionais do Ãcido CaurenÃico

AUTOR(ES)
DATA DE PUBLICAÇÃO

2007

RESUMO

Annona squamosa is a common tree popularly know as âataâ. In the folk medicine is used for treatment of stomach diseases, headache, diarrhea and for removal of louse. Phytochemical investigation of EtOH and hexanic extraction using chromatographic techniques allowed identification of kaurenoic acid an 16b, 17-Dihidroxy-ent-kauran-19-oic acid. Derivative of kaurenoic acid were obtained in order to obtain biological activity and structure elucidation. The hexanic extract of trunk was submmited to hydrolise with KOH/MeOH, followes by methylation to yield ester misture identified by CG-MS as: tetradecanoic acid, penthadecanoic acid, hexadecanoic acid, heptadecanoic acid, octadecadi-9,11-en-oic acid, octadecadi-9,12-en-oic acid, octadec-9-enoic acid, octadecanoic acid. All natural compounds and derivatives were characterized by spectroscopic analysis including NMR 1H and 13C, IV and MS. Compounds structures were confirmed by comparison with literature data.

ASSUNTO(S)

quimica organica kaurenoic acid Ãcido caurÃnico caule de amnona squamosa amnona squamosa stem

ACESSO AO ARTIGO

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