Palladium catalyzed Suzuki cross-coupling of 3-iodo-2-(methylthio)-benzo[b]furan derivatives: synthesis of 3-aryl-2-(methylthio)benzo[b]furans

AUTOR(ES)

Gay, Rafaela M, Manarin, Flávia, Brandão, Ricardo, Zeni, Gilson

FONTE

Journal of the Brazilian Chemical Society

DATA DE PUBLICAÇÃO

2010

RESUMO

Neste trabalho desenvolvemos um método seletivo e eficiente para a síntese de derivados de 3-aril-2-(tiometil)-benzo[b]furanos, via reação de acoplamento com ácidos borônicos, catalisada por paládio. As condições reacionais usadas foram brandas e compatíveis com ácidos borônicos contendo substituintes retiradores, doadores de elétrons ou neutros.

ASSUNTO(S)

palladium suzuki cross-coupling benzofuran boronic acids

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