Benzofuran
Mostrando 1-12 de 26 artigos, teses e dissertações.
-
1. CHEMICAL COMPOSITION OF BIOLOGICAL ACTIVE EXTRACTS OF Tapirira guianensis (ANACARDIACEAE)
This work describes the chemical composition of MeOH seeds and flowers extracts of Tapirira guianensis, a known tree that occurs in the Brazilian Atlantic forest. The CH2Cl2 soluble fraction of seeds extract was submitted to chromatographic procedures to obtain a mixture of new alkenyl dihydrobenzofuranoids which were identified as 2-[(10’Z)-dodec-10’-en
Quím. Nova. Publicado em: 2020-09
-
2. Lipophilicity Study of 1-(Benzofuran-2-yl)ethan-1-one Oxime and its Substituted O-Benzyl Ethers
Heterocyclic oxime ethers play a significant role in organisms due to their biological activity. Lipophilicity is an important parameter that may affect biological activity of the compounds 1-(benzofuran-2-yl)ethan-1-one oxime and its nine biologically active ethers. The relationship between the structure and lipophilicity parameters (log kw values) of the t
J. Braz. Chem. Soc.. Publicado em: 2017-11
-
3. Simultaneous determination of isoproterenol, acetaminophen and folic acid using nanostructured electrochemical sensor based on benzofuran derivative and carbon nanotubes
No presente artigo, o uso de pasta de eletrodo de carbono modificada por nanotubos de carbono e derivados de benzofurano (1-(4-(1,3-ditiolan-2-il)-6,7-dihidroxi-2-metil-6,7-dihidrobenzofuran-3-il) etanona) para a determinação de isoproterenol (IP) foi descrito. O coeficiente de transferência de carga, α, e a constante de transferência de carga, k s, par
J. Braz. Chem. Soc.. Publicado em: 2014-09
-
4. Síntese e avaliação da atividade antinociceptiva de uma benzofuranona derivada da xantoxilina: hipótese sobre o possível mecanismo de ação / Synthesis and evaluation of antihyperalgesic activity of benzofuranone derived of xanthoxyline: hypothesis of the possible mechanism of action
As benzofuranonas são substâncias que podem ser encontradas naturalmente em plantas, bem como a partir da síntese. Algumas destas substâncias apresentam importantes atividades biológicas, como analgésica e anti-inflamatória. Recentemente, foi demonstrado em nossos laboratórios que a 2-(1,3-dihidro-2-benzofuran-1-il)-1-(-2-hidroxi-4,6-dimetoxil)etanon
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/07/2011
-
5. Bagaço do sorgo: estimativa de parâmetros cinéticos e pirólise analítica
Pyrolysis is currently the one of the most important technologies for transforming biomass into more useful products to society. Aiming to deepen the knowledge of the kinetics of pyrolysis, this study conducted an exploratory study of the decomposition of sorghum bagasse by thermogravimetry analysis (TG). The physicochemical characterization of sorghum bagas
Publicado em: 2011
-
6. A novel one-pot three-step synthesis of 2-(1-Benzofuran-2-yl)quinoline-3-carboxylic acid derivatives
Neste trabalho é descrito um protocolo eficiente e simples para a síntese de ácidos 2-(1-benzofurano-2-il)quinolina-3-carboxílicos, envolvendo três etapas realizadas em um único pote: síntese de éter de Williamson, hidrólise do grupo éster na posição 2 da quinolina e ciclização por condensação intramolecular entre o aldeído e o metileno na p
Journal of the Brazilian Chemical Society. Publicado em: 2010
-
7. Palladium catalyzed Suzuki cross-coupling of 3-iodo-2-(methylthio)-benzo[b]furan derivatives: synthesis of 3-aryl-2-(methylthio)benzo[b]furans
Neste trabalho desenvolvemos um método seletivo e eficiente para a síntese de derivados de 3-aril-2-(tiometil)-benzo[b]furanos, via reação de acoplamento com ácidos borônicos, catalisada por paládio. As condições reacionais usadas foram brandas e compatíveis com ácidos borônicos contendo substituintes retiradores, doadores de elétrons ou neutros
Journal of the Brazilian Chemical Society. Publicado em: 2010
-
8. Synthesis of resorcinolic lipids bearing structural similarities to cytosporone A
Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and pro
Química Nova. Publicado em: 2009
-
9. Síntese e avaliação do potencial biológico de chalconas e substâncias relacionadas / Synthesis and evaluation of the biological potential of chalcones and related substances
As chalconas são quimicamente designadas como cetonas α,β - insaturadas com dois anéis aromáticos, um ligado diretamente à função cetona (anel A) e outro à dupla ligação (anel B). Estes compostos podem ser obtidos de fontes naturais ou sinteticamente através de reações de condensação aldólica. Inúmeros estudos têm demonstrado que v
Publicado em: 2009
-
10. An intercalation inhibitor altering the target selectivity of DNA damaging agents: Synthesis of site-specific aflatoxin B1 adducts in a p53 mutational hotspot
Aflatoxin B1 (AFB1) is a potent human carcinogen implicated in the etiology of hepatocellular carcinoma. Upon metabolic activation to the reactive epoxide, AFB1 forms DNA adducts primarily at the N7 position of guanines. To elucidate more fully the molecular mechanism of AFB1-induced mutagenesis, an intercalation inhibitor was designed to probe the effects o
The National Academy of Sciences of the USA.
-
11. Toward the synthesis of the carbacylic ansa antibiotic kendomycin
The convergent synthesis of a benzofuran analog of the carbacyclic ansa compound kendomycin has been achieved by assembling three major fragments by means of epoxide opening and directed ortho lithiation. The crucial tetrahydropyran ring was formed by a highly stereoselective cationic cyclization. Analysis of all synthesized tetrahydropyran-arene compounds r
National Academy of Sciences.
-
12. Cometabolic Degradation of Dibenzofuran by Biphenyl-Cultivated Ralstonia sp. Strain SBUG 290†
Cells of the gram-negative bacterium Ralstonia sp. strain SBUG 290 grown in the presence of biphenyl are able to cooxidize dibenzofuran which has been 1,2-hydroxylated. Meta cleavage of the 1,2-dihydroxydibenzofuran between carbon atoms 1 and 9b produced 2-hydroxy-4-(3′-oxo-3′H-benzofuran-2′-yliden)but-2-enoic acid, which was degraded completely via sa
American Society for Microbiology.