Estudo de associaÃÃo entre doenÃas de risco para o AVCI em dois grupos etÃrios de adultos jovens

AUTOR(ES)
DATA DE PUBLICAÇÃO

2003

RESUMO

Ischemic cerebral vascular accident (ICVA) in young adults is not a frequent occurrence and, therefore, often represents a diagnostic challenge. The aim of the present study was to describe the frequency of risk factors as established in the medical literature, as well as illnesses classically related to cerebral vascular disease among a population of patients between the ages of 15 and 45 years. We reviewed the protocols of 130 patients with a diagnosis of ICVA who were admitted to three tertiary level hospitals in the city of Recife, Pernambuco, Brazil, between June 1992 and December 2002. Among the 130 patients, 68 were women (52.3%). When distributed among age groups, 16.9% (n=22) pertained to Group 1 (15-29 years) and 83.1% (n=108) pertained to Group 2 (30-45 years). All patients had the diagnosis of ICVA confirmed by computerized tomography and/or cerebral magnetic resonance. The patients were also subjected to neurological, cardiologic and laboratorial evaluation. The frequencies of risk factors, whether associated with ICVA or not, were: arterial hypertension (55.4%), smoking (49.2%), hypercolesterolemia (28.5%) and mellitus diabetes (7.7%). The frequencies of possible diseases related to ICVA were: atherotrombotic disease (30.0%), heart disease (23.8%), autoimmune disease (85%), hematological disease (3.1%), and other less common conditions (8.5%). Mitral valve prolapse, the use of oral contraceptives and migraines were considered to be possibly associated with cerebral infarction in the absence of other risk factors or other illnesses associated with ICVA. Undetermined causes corresponded to 26.1% of the cases. Young patients and young adults with ICVA require an extensive and detailed investigation, which should include hematological, cardiologic and arteriographic studies. Using these evaluation criteria, a greater number of diseases related to ICVA can be diagnosed. In this study we concluded that no differences occurred regarding distribution between genders (p=0.159); and that the proportion of patients was significantly higher in the 30 to 40-year age group when compared to the 15 to 29-year age group (p<0.001). Systemic arterial hypertension stood out as the main risk factor for ICVA; and atherothrombosis was the principal condition associated with ICVA

ASSUNTO(S)

ischemic cerebral vascular in young adults fatores de risco risk factors cerebral vascular visease doenÃa cerebrovascular acidente vascular cerebral isquÃmico em jovens medicina

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