Clerodane diterpenes from leaves of Casearia sylvestris Swartz
AUTOR(ES)
Santos, André G. dos, Perez, Carla C., Tininis, Aristeu G., Bolzani, Vanderlan da S., Cavalheiro, Alberto J.
FONTE
Química Nova
DATA DE PUBLICAÇÃO
2007-10
RESUMO
Ethanolic extracts of the leaves of Casearia sylvestris yielded a novel clerodane diterpene, 15-hydroxy-3-cleroden-2-one, together with the known diterpenes (-)-hardwickiic acid, reported for the first time from this species, and casearins B and G, previously isolated from C. sylvestris. The structures of all four compounds were determined by spectrometric analysis. The new clerodane diterpene and (-)-hardwickiic acid contain structural features that are completely different from the highly oxygenated casearins and casearvestrins isolated from C. sylvestris.
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