CefalÃia em portadores de esclerose mÃltipla - caracterizaÃÃo e classificaÃÃo

AUTOR(ES)

Eduardo Raniere Pessoa de Aquino

DATA DE PUBLICAÇÃO

2007

RESUMO

Aiming to characterize headache in multiple sclerosis carriers, attempted at Reference Center for Attention to Carriers of Demyelinating Diseases of Hospital da RestauraÃÃo, Recife, Pernambuco, Brazil, until March 2007, one developed crosssectional study, type series of cases, within convenience sampling, including 60 patients, submitted to directed inquiry of headache signals and symptoms. Variable involved characteristics of: socio-demography, multiple sclerosis and headache. The softwares used were EPI-INFO, version 6.04d, and Statistical Package for Social Sciences, version 13.0, for data organization and analysis, using Qui squared and exact Fisher tests, with significance level equal to 0,05. The research was approved by Ethics Committee from Hospital da RestauraÃÃo. The predominant characteristics were: female:male rate equal 2,33:1,0, 30 - 69 years old (76.7%), medium brown skin (88.4%); married (49.1%), medium or superior scholarship (73.3%), clinical form relapsing/remitting (76.7%) and EDSS between zero and three (8%). Headache was referred by 55% of the patients, corresponding the female:male rate equal to 4,5:1,0, predominantly preceding initial symptoms of multiple sclerosis (75,8%). The prevalences of migraine, tensional headache and trigeminal neuralgia were 45,4%, 30,3% and 3%, respectively. Comparing the groups with and without headache, there was significant predominance amongst women (81.8% against 18,2%), aging from 30 to 69 years (87.9% against 12,1%, of youngest), after 11 to 30 years of disease (48.5% against 77,8% of those with 10 years). Demyelinating lesions in brainstem were significantly more frequent in patients with headache. One has hypothesized that demyelinating lesion in brainstem may be a trigger factor for headache in patients with multiple sclerosis, specially for women, between 30 and 69 years old and with longer disease time

ASSUNTO(S)

cefalÃia headache migrÃnea imagem por ressonÃncia magnÃtica multiple sclerosis migraine imunologia neurologia esclerose mÃltipla magnetic resonance image immunology

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