AplicaÃÃo dos critÃrios diagnÃsticos do lÃpus eritematoso sistÃmico em pacientes com hansenÃase multibacilar

AUTOR(ES)
DATA DE PUBLICAÇÃO

2006

RESUMO

Systemic lupus erithematosus (SLE) it is a chronic nflammatory disease that attacks multiple organs or systems. Without specific clinical manifestation or totally sensitive and specific test laboratorial, the diagnosis of SLE is hindered by the great variety of its presentations. For the diagnosis, the approaches proposed by the American College of Rheumatology are globally used (ACR), accomplished in 1982 and modified in 1997. The presence of four or more of these approaches has sensibility and specificity of 96%. Even so the approaches diagnoses for SLE can have lower specificity in endemic areas for chronic infectious diseases, like similar to that disease. Objectives: establish the prevalence of each one of the approaches diagnoses of SLE proposed by the American College of Rheumatology in 1997, among patient with recent diagnosis of multibacillar leprosy, as well as calculating its specificity and the number of false-positive of the approaches in those sick ones. Patient and Methods: A prevalence study was accomplished, where were applied the approaches diagnoses of SLE proposed by American College of Rheumatology in 1982 and modified in 1997, in the patients with recent diagnosis (up to 6 months) of multibacillar leprosy, besides having calculated the specificity and the number of false-positive of the approaches in that group of sick. The studied population was composed by patients with recent diagnosis (up to 6 months) of multibacillar leprosy, based with the index larger baciloscopic than zero that gave entrance in the national health clinic of leprosy of Clinical Dermatologic of UFPE during the period of the multibacillar leprosy. The prevalence of some of the approaches of SLE were higher than in the healthy population. The approaches with larger prevalence were the malar erithema, the arthritis, the photosensitivity, the limphopenia and the presence of the antiphospholipids antibodies, included in the approach immunologic. Such specificity is much smaller than attributed her to the approaches in 1997 for the American College of Rheumatology. Some present diseases in our, like leprosy in the multibacillar forms, imitate the clinicallaboratorial manifestations of the SLE, what should leave the more attentive professional of health to has SLE

ASSUNTO(S)

medicina approaches diagnoses critÃrios diagnÃsticos lupus eritematoso sistÃmico leprosy hansenÃase systemic lupus erithematosus

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