Apolipoprotein E
Mostrando 25-36 de 458 artigos, teses e dissertações.
-
25. Proteomic analisys of bovine yolk sac / Análise proteômica do saco vitelino de bovinos
The yolk sac plays an important role in embryonic development of all mammals. Its function is being studied, proving to be one of the initials of haematopoiesis. In the period when the placenta is not real yet formed during embryonic development, the yolk sac is the main source of nutrition of the embryo, providing a place for the transfer and synthesis of p
Publicado em: 2009
-
26. Association of ApoE polymorphisms with prevalent hypertension in 1406 older adults: the Bambuí Health Aging Study (BHAS)
Apolipoprotein E (ApoE) polymorphism influences lipid metabolism, but its association with arterial hypertension is controversial. The objective of this study was to examine the association between ApoE polymorphism and prevalent hypertension in a large unselected population of older adults. Participants from the baseline of the Bambuí Health Aging Study wh
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-02
-
27. Avaliação da hiperhomocisteinemia leve na evolução da aterosclerose em camundongos normais, com hemofilia B, deficiencia dos receptores para LDL ou da apolipoproteina E / Evaluation of mild hyperhomocysteinemia in the development of atherosclerosis in normal, hemophiliac B, LDL receptor-deficient or apolipoprotein E-deficient mice
This study evaluated the effect of controlled mild hyperhomocysteinemia (HHcy) in the development of atherosclerosis using normal, apolipoprotein E-deficient (apoE-/-), LDL receptor-deficient (LDLR-/-), or hemophilia B mice. We quantified atherosclerotic lesions at the aortic sinus and analyzed endoplasmic reticulum (RE) stress by western-blot technique. Con
Publicado em: 2008
-
28. The role of clotting factors VIII and IX in the development of atherosclerosis / A interação dos fatores VIII e IX da coagulação no desenvolvimento da doença aterosclerotica
As complicacoes associadas a aterosclerose sao as causas mais comum de morte na populacao ocidental. O entendimento da aterosclerose como uma doenca inflamatoria e a associacao da coagulacao com fenomenos inflamatorios e complicacoes da doenca arterial oferecem novas oportunidades de prevencao e tratamento.Estudos populacionais demonstraram que o risco de in
Publicado em: 2008
-
29. Chylomicron metabolism and lipid reception capacity of high density lipoprotein in metabolic syndrome (MetS) and type 2 diabetes mellitus (DM2) / Metabolismo dos quilomícrons e capacidade da lipoproteína de alta densidade (HDL) de receber lípides na síndrome metabólica e no diabetes mellitus tipo 2
The main metabolic disturbances occurring as a result of type 2 diabetes mellitus (DM2) and Metabolic Syndrome (MetS) are alterations in the metabolism of lipids. It is therefore, important to better understand the aspects by which plasma lipoproteins are metabolized. The evaluation of chylomicron metabolism and lipid transfer of high density lipoprotein (HD
Publicado em: 2008
-
30. Correlation between hypermutation and viral load in patients infected with human immunodeficiency virus type 1 (HIV-1) / Análise de correlação entre eventos de hipermutação e carga viral em pacientes infectados pelo vírus da imunodeficiência humana tipo 1(HIV-1).
INTRODUÇÃO: A substituição monótona de bases G → A no genoma do HIV-1 é observada desde a década de 1990, entretanto, apenas recentemente esse efeito foi atribuído às APOBECs (apolipoprotein B editing catalytic polypeptide) da imunidade inata. As APOBECs celulares atuam na deaminação de citidina a uridina na fita de DNA viral de polaridade n
Publicado em: 2008
-
31. Purification, partial characterization and role in lipid transport to developing oocytes of a novel lipophorin from the cowpea weevil, Callosobruchus maculatus
Lipid transport in arthropods is achieved by highly specialized lipoproteins, which resemble those described in vertebrate blood. Here we describe purification and characterization of the lipid-apolipoprotein complex, lipophorin (Lp), from adults and larvae of the cowpea weevil Callosobruchus maculatus. We also describe the Lp-mediated lipid transfer to deve
Brazilian Journal of Medical and Biological Research. Publicado em: 17/12/2007
-
32. Apolipoprotein E polymorphism distribution in an elderly Brazilian population: the Bambuí Health and Aging Study
Apolipoprotein E (ApoE) is one of the most extensively studied genes in the context of aging, but there are few population-based studies on ApoE polymorphism in the elderly in developing countries. The objective of the present study was to assess ApoE allele and genotype distribution in a large elderly community-based sample and its association with age, sex
Brazilian Journal of Medical and Biological Research. Publicado em: 22/10/2007
-
33. Comparison of apolipoprotein E polymorphism and other atherosclerotic risk factors in two portuguese populations: the influence of insularity
O principal objectivo deste estudo é o de pesquisar o efeito da insularidade nos polimorfismos da apolipoproteína (apo) E em indivíduos saudáveis do continente (Lisboa) e de Ponta Delgada (Ilha de S. Miguel, Arquipélago dos Açores). Adicionalmente, estudar a distribuição dos seus genótipos em doentes com aterosclerose da Ilha de S. Miguel. Em Lisboa
Brazilian Archives of Biology and Technology. Publicado em: 2007-09
-
34. Lipoprotein lipase PvuII polymorphism is associated with variations in serum lipid levels in non-diabetic pregnant women
The aim of the present study was to determine if there is an association between the single nucleotide polymorphisms (SNPs) of the lipoprotein lipase (LPL) and apolipoprotein E (apo E) genes and the serum lipid profile in pregnancy and puerperium. Non-diabetic women of European descent in the third semester of pregnancy (N = 120) were selected. Those with di
Brazilian Journal of Medical and Biological Research. Publicado em: 05/04/2007
-
35. Relevance of apolipoprotein E4 for the lipid profile of Brazilian patients with coronary artery disease
Apolipoprotein E (apoE - e2, e3, e4 alleles) plays a role in the regulation of lipid metabolism, with the e4 considered to be a risk factor for coronary artery disease (CAD). We aimed to evaluate the apoE polymorphisms in Brazilians with CAD and their influence on the lipid profile and other risk factors (hypertension, diabetes mellitus, smoking). Two hundre
Brazilian Journal of Medical and Biological Research. Publicado em: 06/01/2007
-
36. Apolipoprotein E polymorphism in Brazilian dyslipidemic individuals: Ouro Preto study
The influence of apolipoprotein E alleles and genotypes on plasma lipid levels was determined in 185 individuals of mixed ethnicity living in Ouro Preto, Brazil. DNA was obtained from blood samples and the genotypes were determined by an RFLP-PCR procedure. The *3 allele was the most frequent (72%), followed by *4 (20%) and *2 (8%); *4 frequency was higher a
Brazilian Journal of Medical and Biological Research. Publicado em: 2007-01