Anticoagulant Activity
Mostrando 25-36 de 166 artigos, teses e dissertações.
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25. Ação de polissacarídeos sulfatados de Fucus Vesiculosus na Hemostasia e no sistema complemento
Fucans are a family of sulfated homo and teropolysaccharides respectively, composed mainly of a- (12) and a- (13) linked by L-fucose residues. Properties such as the ability to act as an anti-contraceptive, to reduce cholesterol levels, and to act as an anti-tumor agent are much related. We have focused our attention on the anticoagulant properties, platelet
Publicado em: 2006
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26. Polissacarídeos sulfatados de interesse farmacológico no camarão litopenaeus schimitti
Sulfated Polysaccharides with unique chemical structures and important biological activities has been found in a diversity of sea invertebrates. For that, to exist a huger interest on the biotechnology field in the research theses sulfated compounds isolated from sea organisms. Despite the privileged brazilian position for these compounds attainment, there a
Publicado em: 2006
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27. AlteraÃÃo bioquÃmica em fator de coagulaÃÃo como causa de trombose venosa profunda â relato de caso clÃnico
Deep venous thrombosis (DVT) in the pediatric population (0-18 year old) has been reported as lower than in adults. In almost half of the children, three or four risk factors for thrombosis are present simultaneously. Even in children with thromboembolic disturbance, thrombosis did not occur spontaneously; the hemostatic defect became apparent because thromb
Publicado em: 2006
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28. Identificação e caracterização funcional de atividade apirásica nas salivas de triatomíneos vetores da Doença de Chagas
Blood-feeding arthropods are able to constraints barriers imposed by host defenses, due to the presence of a wide range of antihemostatic factors in their saliva, including vasodilators, antiplatelet factors and anticoagulant. The main Chagas disease transmission mechanism is contamination of a host by faeces from triatominae infected. Triatoma infestans Klu
Publicado em: 2006
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29. Homogalactanas sulfatadas da alga Codium isthmocladum com atividade anticoagulante
Desde a primeira descrição de polissacarídeos sulfatados em algas marinhas, as atividades biológicas destes compostos foram avaliadas sob diferentes aspectos e procedimentos experimentais. Dentre as diversas atividades biológicas apresentadas pelos polissacarídeos de algas marinhas, a ação do anticoagulante aparece como sendo uma função promissora.
Publicado em: 2006
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30. Purification and investigation of the physical-chemical protease inhibitors properties from acacia plumosa lowe seeds. / Purificação e investigação de propriedades físico-químicas de inibidores de proteases extraídos das sementes de aácia plumosa Lowe.
Seeds of plants belonging to Leguminosae family are rich sources of protease inhibitors. The Acacia genus is one of the most important members of this group. In this work, novel protease inhibitors from Acacia plumose Lowe seeds have been described. From the saline extract of mature seeds, the inhibitors were purified by size exclusion chromatography on Supe
Publicado em: 2006
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31. Partial characterization and anticoagulant activity of a heterofucan from the brown seaweed Padina gymnospora
The brown algae Padina gymnospora contain different fucans. Powdered algae were submitted to proteolysis with the proteolytic enzyme maxataze. The first extract of the algae was constituted of polysaccharides contaminated with lipids, phenols, etc. Fractionation of the fucans with increasing concentrations of acetone produced fractions with different proport
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-04
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32. Role of protein present in the ink released by-the-sea slug Aplysia dactylomela Rang in 1828 in defense mechanisms of the animal / Papel de proteínas presentes na tinta liberada pela lesma-do-mar Aplysia dactylomela Rang 1828 nos mecanismos de defesa do animal
The marine gastropod Aplysia dactylomela is known to release a purple ink when it is plagued. How has no external structure of protection, it is believed that secretion, rich in biologically active substances, participate in the chemical defense of the animal. The ink is composed of pigments, proteins and low molecular weight substances. The pigments of ink
Publicado em: 2005
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33. Purificação e caracterização parcial de uma Fucana C de Dictyota mentrualis e estudo do seu efeito antiinflamatório e nociceptivo
In recent years, sulfated polysaccharides from marine algae have emerged as an important class of natural biopolymers with potential application in human and veterinary health care, while taking advantage of the absence of potential risk of contamination by animal viruses. Among these, fucans isolated from the cell walls of marine brown alga have been study
Publicado em: 2005
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34. Heterofucans from Dictyota menstrualis have anticoagulant activity
Fucan is a term used to denote a family of sulfated L-fucose-rich polysaccharides which are present in the extracellular matrix of brown seaweed and in the egg jelly coat of sea urchins. Plant fucans have several biological activities, including anticoagulant and antithrombotic, related to the structural and chemical composition of polysaccharides. We have e
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-02
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35. ViabilizaÃÃo da heparina como suporte para carrear gentamicina
Many polymers used as drug carriers in controlled delivery systems are polysaccharides. This work propose the use of glycosaminoglycan heparin as carrier for the aminoglycosidic antibiotic gentamicin. Due to their chemical feature, these compounds possess an intrinsic ionic affinity, nevertheless, a carbodiimide was used to promote covalent binding (amide bo
Publicado em: 2002
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36. Effect of collection, transport, processing and storage of blood specimens on the activity of lysosomal enzymes in plasma and leukocytes
This study was designed to evaluate the effect of different conditions of collection, transport and storage on the quality of blood samples from normal individuals in terms of the activity of the enzymes ß-glucuronidase, total hexosaminidase, hexosaminidase A, arylsulfatase A and ß-galactosidase. The enzyme activities were not affected by the different mat
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-09